Aryllithium compounds bearing alkoxycarbonyl groups: Generation and reactions using a microflow system

Aiichiro Nagaki, Heejin Kim, Jun Ichi Yoshida

Research output: Contribution to journalArticle

120 Citations (Scopus)


Go with the flow: An effective method for the generation and reaction of aryllithium compounds bearing an alkoxycarbonyl group is developed using microflow systems with very short residence times together with fast mixing and efficient temperature control. A wide range of alkoxycarbonyl groups including ethoxycarbonyl and methoxycarbonyl groups are tolerant of the microflow conditions. (Chemical Equation Presented)

Original languageEnglish
Pages (from-to)7833-7836
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number41
Publication statusPublished - 2008 Sep 29
Externally publishedYes



  • Arenes
  • Electrophilic substitution
  • Lithiation
  • Microreactors
  • Reactive intermediates

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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