Assessment of left ventricular function by analysis of volume-time curves of 16 segments with real-time three dimensional echocardiography: Left ventricular asynchrony as a clinical parameter for patients with heart failure

Seong-Mi Park, Gi Chang Kim, Min Jae Jeon, Chang Kun Lee, Dae Hyeok Kim, Keum Soo Park, Woo Hyung Lee, Jun Kwan

Research output: Contribution to journalArticle

Abstract

Background and Objectives : Recent technical developments with high-resolution real-time 3-dimensional echocardiography (RT3DE) have facilitated the acquisition of high quality images and the analysis of segmental volume-time curves (VTCs). The purposes of this study were to assess left ventricular (LV) asynchrony with using the VTCs of 16 segments by RT3DE and to compare this with tissue Doppler imaging (TDI) as a clinical parameter. Subjects and Methods : Twenty-three heart failure (HF) patients (LVEF: 25 ± 6%, age: 60 ± 13 years) and 16 normal controls underwent TDI and RT3DE at baseline and 1-year. The standard deviation (803) of the end systolic time to reach the minimal systolic volume for the 16 segments on VTCs was obtained by RT3DE. The standard deviation (SD 2) of the electromechanical coupling time for the 8 segments was measured using TDI. Results : SD 3 was markedly higher in the HF patients than that in the controls (7.7 ± 2.5 vs 1.5 ± 1.0%, respectively, p<0.01) and it increased as the LVEF decreased (r=-0.85, p<0.01). SD 2 was also significantly higher in the HF patients (27.0±8.6 vs 12.6±5.0 msec, respectively, p<0.01) and it had good negative correlation with the LVEF (r=-0.72, p<0.01). SD 3 was well correlated with SD 2 (r=0.66, p<0.01). At 1-year, the HF patients with an increased LVEF showed a decreased SD 3 (7/13). In contrast, the patients with a decreased LVEF had an increased SD 3 (3/13). Conclusion : The analysis of VTCs for the 16 LV segments with using RT3DE from a single acoustic window may be a useful clinical parameter for evaluating the LV function, including LV asynchrony, the LV volume and the LVEF.

Original languageEnglish
Pages (from-to)669-675
Number of pages7
JournalKorean Circulation Journal
Volume36
Issue number10
Publication statusPublished - 2006 Oct 1

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Three-Dimensional Echocardiography
Left Ventricular Function
Heart Failure
Echocardiography
Acoustics

Keywords

  • Echocardiography
  • Heart failure

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Assessment of left ventricular function by analysis of volume-time curves of 16 segments with real-time three dimensional echocardiography : Left ventricular asynchrony as a clinical parameter for patients with heart failure. / Park, Seong-Mi; Kim, Gi Chang; Jeon, Min Jae; Lee, Chang Kun; Kim, Dae Hyeok; Park, Keum Soo; Lee, Woo Hyung; Kwan, Jun.

In: Korean Circulation Journal, Vol. 36, No. 10, 01.10.2006, p. 669-675.

Research output: Contribution to journalArticle

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title = "Assessment of left ventricular function by analysis of volume-time curves of 16 segments with real-time three dimensional echocardiography: Left ventricular asynchrony as a clinical parameter for patients with heart failure",
abstract = "Background and Objectives : Recent technical developments with high-resolution real-time 3-dimensional echocardiography (RT3DE) have facilitated the acquisition of high quality images and the analysis of segmental volume-time curves (VTCs). The purposes of this study were to assess left ventricular (LV) asynchrony with using the VTCs of 16 segments by RT3DE and to compare this with tissue Doppler imaging (TDI) as a clinical parameter. Subjects and Methods : Twenty-three heart failure (HF) patients (LVEF: 25 ± 6{\%}, age: 60 ± 13 years) and 16 normal controls underwent TDI and RT3DE at baseline and 1-year. The standard deviation (803) of the end systolic time to reach the minimal systolic volume for the 16 segments on VTCs was obtained by RT3DE. The standard deviation (SD 2) of the electromechanical coupling time for the 8 segments was measured using TDI. Results : SD 3 was markedly higher in the HF patients than that in the controls (7.7 ± 2.5 vs 1.5 ± 1.0{\%}, respectively, p<0.01) and it increased as the LVEF decreased (r=-0.85, p<0.01). SD 2 was also significantly higher in the HF patients (27.0±8.6 vs 12.6±5.0 msec, respectively, p<0.01) and it had good negative correlation with the LVEF (r=-0.72, p<0.01). SD 3 was well correlated with SD 2 (r=0.66, p<0.01). At 1-year, the HF patients with an increased LVEF showed a decreased SD 3 (7/13). In contrast, the patients with a decreased LVEF had an increased SD 3 (3/13). Conclusion : The analysis of VTCs for the 16 LV segments with using RT3DE from a single acoustic window may be a useful clinical parameter for evaluating the LV function, including LV asynchrony, the LV volume and the LVEF.",
keywords = "Echocardiography, Heart failure",
author = "Seong-Mi Park and Kim, {Gi Chang} and Jeon, {Min Jae} and Lee, {Chang Kun} and Kim, {Dae Hyeok} and Park, {Keum Soo} and Lee, {Woo Hyung} and Jun Kwan",
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T2 - Left ventricular asynchrony as a clinical parameter for patients with heart failure

AU - Park, Seong-Mi

AU - Kim, Gi Chang

AU - Jeon, Min Jae

AU - Lee, Chang Kun

AU - Kim, Dae Hyeok

AU - Park, Keum Soo

AU - Lee, Woo Hyung

AU - Kwan, Jun

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AB - Background and Objectives : Recent technical developments with high-resolution real-time 3-dimensional echocardiography (RT3DE) have facilitated the acquisition of high quality images and the analysis of segmental volume-time curves (VTCs). The purposes of this study were to assess left ventricular (LV) asynchrony with using the VTCs of 16 segments by RT3DE and to compare this with tissue Doppler imaging (TDI) as a clinical parameter. Subjects and Methods : Twenty-three heart failure (HF) patients (LVEF: 25 ± 6%, age: 60 ± 13 years) and 16 normal controls underwent TDI and RT3DE at baseline and 1-year. The standard deviation (803) of the end systolic time to reach the minimal systolic volume for the 16 segments on VTCs was obtained by RT3DE. The standard deviation (SD 2) of the electromechanical coupling time for the 8 segments was measured using TDI. Results : SD 3 was markedly higher in the HF patients than that in the controls (7.7 ± 2.5 vs 1.5 ± 1.0%, respectively, p<0.01) and it increased as the LVEF decreased (r=-0.85, p<0.01). SD 2 was also significantly higher in the HF patients (27.0±8.6 vs 12.6±5.0 msec, respectively, p<0.01) and it had good negative correlation with the LVEF (r=-0.72, p<0.01). SD 3 was well correlated with SD 2 (r=0.66, p<0.01). At 1-year, the HF patients with an increased LVEF showed a decreased SD 3 (7/13). In contrast, the patients with a decreased LVEF had an increased SD 3 (3/13). Conclusion : The analysis of VTCs for the 16 LV segments with using RT3DE from a single acoustic window may be a useful clinical parameter for evaluating the LV function, including LV asynchrony, the LV volume and the LVEF.

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