Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men

A 12-years follow-up study

Dae Yeon Lee, Min Gyu Yoo, Hyo Jin Kim, Han Byul Jang, Jae-Hong Kim, Hye Ja Lee, Sang Ick Park

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into four groups - based on the baseline (one-point measure; non-drinking, <5 g/day, ≥5, <30 g/day, and ≥30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, ≥30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95% CI, 1.10-1.85), but ≥5, <30 g/day alcohol consumption had no effects on the incident diabetes. Meanwhile, when using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32, 1.01-1.73), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66; 0.50-0.87 and HR: 0.74; 0.57-0.95, respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups. Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.

Original languageEnglish
Article number7322
JournalScientific Reports
Volume7
Issue number1
DOIs
Publication statusPublished - 2017 Dec 1

Fingerprint

compound A 12
Alcohol Drinking
Type 2 Diabetes Mellitus
Incidence
Drinking
Insulin Resistance
Light
Cohort Studies
Alcohols

ASJC Scopus subject areas

  • General

Cite this

Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men : A 12-years follow-up study. / Lee, Dae Yeon; Yoo, Min Gyu; Kim, Hyo Jin; Jang, Han Byul; Kim, Jae-Hong; Lee, Hye Ja; Park, Sang Ick.

In: Scientific Reports, Vol. 7, No. 1, 7322, 01.12.2017.

Research output: Contribution to journalArticle

Lee, Dae Yeon ; Yoo, Min Gyu ; Kim, Hyo Jin ; Jang, Han Byul ; Kim, Jae-Hong ; Lee, Hye Ja ; Park, Sang Ick. / Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men : A 12-years follow-up study. In: Scientific Reports. 2017 ; Vol. 7, No. 1.
@article{e8d1579bf9a3439abda3ddc117305be4,
title = "Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study",
abstract = "Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into four groups - based on the baseline (one-point measure; non-drinking, <5 g/day, ≥5, <30 g/day, and ≥30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, ≥30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95{\%} CI, 1.10-1.85), but ≥5, <30 g/day alcohol consumption had no effects on the incident diabetes. Meanwhile, when using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32, 1.01-1.73), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66; 0.50-0.87 and HR: 0.74; 0.57-0.95, respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups. Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.",
author = "Lee, {Dae Yeon} and Yoo, {Min Gyu} and Kim, {Hyo Jin} and Jang, {Han Byul} and Jae-Hong Kim and Lee, {Hye Ja} and Park, {Sang Ick}",
year = "2017",
month = "12",
day = "1",
doi = "10.1038/s41598-017-07549-2",
language = "English",
volume = "7",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
number = "1",

}

TY - JOUR

T1 - Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men

T2 - A 12-years follow-up study

AU - Lee, Dae Yeon

AU - Yoo, Min Gyu

AU - Kim, Hyo Jin

AU - Jang, Han Byul

AU - Kim, Jae-Hong

AU - Lee, Hye Ja

AU - Park, Sang Ick

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into four groups - based on the baseline (one-point measure; non-drinking, <5 g/day, ≥5, <30 g/day, and ≥30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, ≥30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95% CI, 1.10-1.85), but ≥5, <30 g/day alcohol consumption had no effects on the incident diabetes. Meanwhile, when using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32, 1.01-1.73), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66; 0.50-0.87 and HR: 0.74; 0.57-0.95, respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups. Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.

AB - Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into four groups - based on the baseline (one-point measure; non-drinking, <5 g/day, ≥5, <30 g/day, and ≥30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, ≥30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95% CI, 1.10-1.85), but ≥5, <30 g/day alcohol consumption had no effects on the incident diabetes. Meanwhile, when using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32, 1.01-1.73), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66; 0.50-0.87 and HR: 0.74; 0.57-0.95, respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups. Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.

UR - http://www.scopus.com/inward/record.url?scp=85026798815&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026798815&partnerID=8YFLogxK

U2 - 10.1038/s41598-017-07549-2

DO - 10.1038/s41598-017-07549-2

M3 - Article

VL - 7

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 7322

ER -