Abstract
Background: The objective of this study was to examine the association between low blood lead levels of <5 μg/dL and the development of dental caries among children. Methods: The Children's Health and Environment Research (CHEER) group recruited a cohort of 7,059 school-aged children from six Korean cities. The final study populations in the permanent and deciduous teeth groups were 1,564 and 1,241 children, respectively, after excluding 4 children with blood lead levels of >5 μg/dL. Compared with the children who did not have dental caries, the risk of having dental caries according to blood lead level was estimated by using the zero-inflated negative binomial model. Results: The geometric mean (geometric standard deviation, maximum) blood lead level was 1.53 μg/dL (1.57, 4.89 μg/dL), and 74.4% of children had a level of <2 μg/dL. Blood lead level was significantly higher in the children with than in those without deciduous dental caries (1.59 vs. 1.51 μg/dL), similarly with permanent dental caries (1.65 vs. 1.51 μg/dL). After adjustment for covariates, deciduous teeth surfaces that were decayed and filled increased significantly with increasing blood lead levels in a dose-dependent manner (prevalence ratio, 1.14; 95% confidence interval: 1.02-1.27). However, the risk of having dental caries in permanent teeth was not linearly associated with the increase in blood lead level. Conclusions: In the sum of decayed and filled surfaces, we found a significant increase in risk of dental caries of the deciduous teeth with an increase in blood lead levels (<5 μg/dL) but found no statistical significance in the association with decayed and filled surfaces of caries separately.
| Original language | English |
|---|---|
| Article number | 42 |
| Journal | BMC Oral Health |
| Volume | 17 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2017 Jan 13 |
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Keywords
- Blood lead
- Children
- Deciduous dentition
- Dental caries
ASJC Scopus subject areas
- Dentistry(all)
Cite this
Association between Low blood lead levels and increased risk of dental caries in children : A cross-sectional study. / Kim, Young Suk; Ha, Mina; Kwon, Ho Jang; Kim, Hae-Young; Choi, Youn Hee.
In: BMC Oral Health, Vol. 17, No. 1, 42, 13.01.2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Association between Low blood lead levels and increased risk of dental caries in children
T2 - A cross-sectional study
AU - Kim, Young Suk
AU - Ha, Mina
AU - Kwon, Ho Jang
AU - Kim, Hae-Young
AU - Choi, Youn Hee
PY - 2017/1/13
Y1 - 2017/1/13
N2 - Background: The objective of this study was to examine the association between low blood lead levels of <5 μg/dL and the development of dental caries among children. Methods: The Children's Health and Environment Research (CHEER) group recruited a cohort of 7,059 school-aged children from six Korean cities. The final study populations in the permanent and deciduous teeth groups were 1,564 and 1,241 children, respectively, after excluding 4 children with blood lead levels of >5 μg/dL. Compared with the children who did not have dental caries, the risk of having dental caries according to blood lead level was estimated by using the zero-inflated negative binomial model. Results: The geometric mean (geometric standard deviation, maximum) blood lead level was 1.53 μg/dL (1.57, 4.89 μg/dL), and 74.4% of children had a level of <2 μg/dL. Blood lead level was significantly higher in the children with than in those without deciduous dental caries (1.59 vs. 1.51 μg/dL), similarly with permanent dental caries (1.65 vs. 1.51 μg/dL). After adjustment for covariates, deciduous teeth surfaces that were decayed and filled increased significantly with increasing blood lead levels in a dose-dependent manner (prevalence ratio, 1.14; 95% confidence interval: 1.02-1.27). However, the risk of having dental caries in permanent teeth was not linearly associated with the increase in blood lead level. Conclusions: In the sum of decayed and filled surfaces, we found a significant increase in risk of dental caries of the deciduous teeth with an increase in blood lead levels (<5 μg/dL) but found no statistical significance in the association with decayed and filled surfaces of caries separately.
AB - Background: The objective of this study was to examine the association between low blood lead levels of <5 μg/dL and the development of dental caries among children. Methods: The Children's Health and Environment Research (CHEER) group recruited a cohort of 7,059 school-aged children from six Korean cities. The final study populations in the permanent and deciduous teeth groups were 1,564 and 1,241 children, respectively, after excluding 4 children with blood lead levels of >5 μg/dL. Compared with the children who did not have dental caries, the risk of having dental caries according to blood lead level was estimated by using the zero-inflated negative binomial model. Results: The geometric mean (geometric standard deviation, maximum) blood lead level was 1.53 μg/dL (1.57, 4.89 μg/dL), and 74.4% of children had a level of <2 μg/dL. Blood lead level was significantly higher in the children with than in those without deciduous dental caries (1.59 vs. 1.51 μg/dL), similarly with permanent dental caries (1.65 vs. 1.51 μg/dL). After adjustment for covariates, deciduous teeth surfaces that were decayed and filled increased significantly with increasing blood lead levels in a dose-dependent manner (prevalence ratio, 1.14; 95% confidence interval: 1.02-1.27). However, the risk of having dental caries in permanent teeth was not linearly associated with the increase in blood lead level. Conclusions: In the sum of decayed and filled surfaces, we found a significant increase in risk of dental caries of the deciduous teeth with an increase in blood lead levels (<5 μg/dL) but found no statistical significance in the association with decayed and filled surfaces of caries separately.
KW - Blood lead
KW - Children
KW - Deciduous dentition
KW - Dental caries
UR - http://www.scopus.com/inward/record.url?scp=85010333116&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85010333116&partnerID=8YFLogxK
U2 - 10.1186/s12903-017-0335-z
DO - 10.1186/s12903-017-0335-z
M3 - Article
C2 - 28086936
AN - SCOPUS:85010333116
VL - 17
JO - BMC Oral Health
JF - BMC Oral Health
SN - 1472-6831
IS - 1
M1 - 42
ER -