Association Between Microbiota and Nasal Mucosal Diseases in terms of Immunity

Junhu Tai, Mun Soo Han, Jiwon Kwak, Tae Hoon Kim

Research output: Contribution to journalReview articlepeer-review

Abstract

The pathogenesis of nasal inflammatory diseases is related to various factors such as anatomical structure, heredity, and environment. The nasal microbiota play a key role in coordinating immune system functions. Dysfunction of the microbiota has a significant impact on the occurrence and development of nasal inflammation. This review will introduce the positive and negative roles of microbiota involved in immunity surrounding nasal mucosal diseases such as chronic sinusitis and allergic rhinitis. In addition, we will also introduce recent developments in DNA sequencing, metabolomics, and proteomics combined with computation-based bioinformatics.

Original languageEnglish
JournalInternational journal of molecular sciences
Volume22
Issue number9
DOIs
Publication statusPublished - 2021 Apr 29

Keywords

  • allergic rhinitis
  • chronic rhinosinusitis
  • immunity
  • microbiota
  • nasal mucosa

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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