Association Between Waist Circumference and Dementia in Older Persons: A Nationwide Population-Based Study

Geum Joon Cho, Soon Young Hwang, Kyu Min Lee, Kyung Mook Choi, Sei Hyun Baik, Tak Kim, Sung Won Han, Hye Jin Yoo

Research output: Contribution to journalArticle

Abstract

Objective: This study examined whether a positive association exists between waist circumference (WC) and dementia among older persons. Methods: The study population comprised 872,082 participants aged 65 years and older who participated in a Korean national health screening examination between January 1, 2009, and December 31, 2009. Adjusted hazard ratios and 95% CIs for dementia during follow-up from 2009 to 2015 were calculated according to baseline BMI and WC categories. Results: After a multivariate adjustment that included BMI, the hazard ratios for dementia showed a stepwise increase according to the increase in WC categories by 5 cm from 85 to 90 cm in men and from 80 to 85 cm in women until ≥ 110 cm (from 1.06 [95% CI: 1.03-1.09] to 1.64 [95% CI: 1.37-1.94] in men and from 1.04 [95% CI: 1.02-1.07] to 1.58 [95% CI: 1.36-1.84] in women). The influence of the current WC category for abdominal obesity on the risk of dementia was different according to BMI; especially, the normal weight men and women with abdominal obesity had a prominent increased risk of dementia compared with those without abdominal obesity. Conclusions: Abdominal obesity, as measured by WC, was associated with significantly increased risk of dementia after adjustment for general obesity.

Original languageEnglish
Pages (from-to)1883-1891
Number of pages9
JournalObesity
Volume27
Issue number11
DOIs
Publication statusPublished - 2019 Nov 1

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ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

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