TY - JOUR
T1 - Association of food consumption during pregnancy with mercury and lead levels in cord blood
AU - Kim, Jin Hee
AU - Lee, Su Jin
AU - Kim, Su Young
AU - Choi, Gyuyeon
AU - Lee, Jeong Jae
AU - Kim, Hai Joong
AU - Kim, Sungjoo
AU - Park, Jeongim
AU - Moon, Hyo Bang
AU - Choi, Kyungho
AU - Kim, Sungkyoon
AU - Choi, Soo ran
N1 - Funding Information:
This study was supported by the Korea Food and Drug Administration ( 12162KFDA731 ). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - In utero exposure to mercury and lead has been linked to various adverse health effects related to growth and development. However, there was no evidence on the relationship between food consumption during pregnancy and mercury or lead level in cord blood. Therefore we measured mercury and lead levels in bloods, urines, and cord bloods obtained from 302 pregnant women and estimated relationships between food consumption during pregnancy and mercury or lead level in cord blood to identify perinatal mercury and lead exposures originated from foods during pregnancy. Relationship between food consumption and mercury or lead level was estimated using a generalized linear model after adjustment for body mass index (BMI), delivery experience, income, recruitment year, and other dietary factors for mercury and age, BMI, cesarean section, delivery experience, recruitment year, and other dietary factors for lead. Fish consumption was positively associated with mercury level in cord blood (p = 0.0135), while cereal and vegetable consumptions were positively associated with lead level in cord blood (p = 0.0517 for cereal and p = 0.0504 for vegetable). Furthermore, tea consumption restrained increase of lead level in cord blood (p = 0.0014). Our findings support that mercury or lead exposure in Korean pregnant women may come from frequent fish and cereal or vegetable consumption while tea consumption may decrease lead exposure in pregnant women. Therefore, careful intervention through food consumption should be considered.
AB - In utero exposure to mercury and lead has been linked to various adverse health effects related to growth and development. However, there was no evidence on the relationship between food consumption during pregnancy and mercury or lead level in cord blood. Therefore we measured mercury and lead levels in bloods, urines, and cord bloods obtained from 302 pregnant women and estimated relationships between food consumption during pregnancy and mercury or lead level in cord blood to identify perinatal mercury and lead exposures originated from foods during pregnancy. Relationship between food consumption and mercury or lead level was estimated using a generalized linear model after adjustment for body mass index (BMI), delivery experience, income, recruitment year, and other dietary factors for mercury and age, BMI, cesarean section, delivery experience, recruitment year, and other dietary factors for lead. Fish consumption was positively associated with mercury level in cord blood (p = 0.0135), while cereal and vegetable consumptions were positively associated with lead level in cord blood (p = 0.0517 for cereal and p = 0.0504 for vegetable). Furthermore, tea consumption restrained increase of lead level in cord blood (p = 0.0014). Our findings support that mercury or lead exposure in Korean pregnant women may come from frequent fish and cereal or vegetable consumption while tea consumption may decrease lead exposure in pregnant women. Therefore, careful intervention through food consumption should be considered.
KW - Food consumption
KW - Mercury and lead exposures
KW - Pregnant women
UR - http://www.scopus.com/inward/record.url?scp=84964550181&partnerID=8YFLogxK
U2 - 10.1016/j.scitotenv.2016.04.082
DO - 10.1016/j.scitotenv.2016.04.082
M3 - Article
C2 - 27135573
AN - SCOPUS:84964550181
SN - 0048-9697
VL - 563-564
SP - 118
EP - 124
JO - Science of the Total Environment
JF - Science of the Total Environment
ER -