Association of habitual snoring with glucose and insulin metabolism in nonobese Korean adult men

Chol Shin, JinYoung Kim, Je Hyeong Kim, Sang Yeub Lee, Jae Jeong Shim, Kwang Ho In, KyungHo Kang, SeHwa Yoo, NamHan Cho, KuChan Kimm, Soonjae Joo

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Habitual snoring is associated with cardiovascular morbidity and mortality, and metabolic abnormalities such as impaired glucose homeostasis. Many studies were performed in obese Western populations. The purpose of this study was to examine the association of habitual snoring with glucose and insulin metabolism in nonobese Korean men who were free of diabetes and hypertension. A total of 2,719 men ages 40-69 years from the Korean Health and Genome Study participated in this study. Information of snoring frequency was obtained by a questionnaire and glucose and insulin levels during oral glucose tolerance test were measured. Repeated measures analysis of variance detected significant differences in the changing patterns of glucose and insulin levels at 1 hour and 2 hours between habitual snorers and nonhabitual snorers, whereas there were no significant differences in fasting blood glucose and insulin levels. Multivariate logistic regression analyses revealed that habitual snoring was independently associated with elevated 1-hour and 2-hour glucose levels and a 2-hour insulin level, respectively. The present data suggest that habitual snoring may affect glucose-insulin metabolism, independent of diabetes and hypertension, even in nonobese Korean middle-age men. Further prospective studies are needed to examine the causal relationship between habitual snoring and insulin resistance or glucose intolerance.

Original languageEnglish
Pages (from-to)287-291
Number of pages5
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume171
Issue number3
DOIs
Publication statusPublished - 2005 Feb 1

Fingerprint

Snoring
Insulin
Glucose
Hypertension
Glucose Intolerance
Glucose Tolerance Test
Insulin Resistance
Blood Glucose
Fasting
Analysis of Variance
Homeostasis
Logistic Models
Regression Analysis
Genome
Prospective Studies
Morbidity
Mortality
Health
Population

Keywords

  • Epidemiology
  • Glucose tolerance
  • Insulin resistance
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Association of habitual snoring with glucose and insulin metabolism in nonobese Korean adult men. / Shin, Chol; Kim, JinYoung; Kim, Je Hyeong; Lee, Sang Yeub; Shim, Jae Jeong; In, Kwang Ho; Kang, KyungHo; Yoo, SeHwa; Cho, NamHan; Kimm, KuChan; Joo, Soonjae.

In: American Journal of Respiratory and Critical Care Medicine, Vol. 171, No. 3, 01.02.2005, p. 287-291.

Research output: Contribution to journalArticle

@article{964c3b6e220d42c594e96708ad58dd8b,
title = "Association of habitual snoring with glucose and insulin metabolism in nonobese Korean adult men",
abstract = "Habitual snoring is associated with cardiovascular morbidity and mortality, and metabolic abnormalities such as impaired glucose homeostasis. Many studies were performed in obese Western populations. The purpose of this study was to examine the association of habitual snoring with glucose and insulin metabolism in nonobese Korean men who were free of diabetes and hypertension. A total of 2,719 men ages 40-69 years from the Korean Health and Genome Study participated in this study. Information of snoring frequency was obtained by a questionnaire and glucose and insulin levels during oral glucose tolerance test were measured. Repeated measures analysis of variance detected significant differences in the changing patterns of glucose and insulin levels at 1 hour and 2 hours between habitual snorers and nonhabitual snorers, whereas there were no significant differences in fasting blood glucose and insulin levels. Multivariate logistic regression analyses revealed that habitual snoring was independently associated with elevated 1-hour and 2-hour glucose levels and a 2-hour insulin level, respectively. The present data suggest that habitual snoring may affect glucose-insulin metabolism, independent of diabetes and hypertension, even in nonobese Korean middle-age men. Further prospective studies are needed to examine the causal relationship between habitual snoring and insulin resistance or glucose intolerance.",
keywords = "Epidemiology, Glucose tolerance, Insulin resistance, Sleep-disordered breathing",
author = "Chol Shin and JinYoung Kim and Kim, {Je Hyeong} and Lee, {Sang Yeub} and Shim, {Jae Jeong} and In, {Kwang Ho} and KyungHo Kang and SeHwa Yoo and NamHan Cho and KuChan Kimm and Soonjae Joo",
year = "2005",
month = "2",
day = "1",
doi = "10.1164/rccm.200407-906OC",
language = "English",
volume = "171",
pages = "287--291",
journal = "American Journal of Respiratory and Critical Care Medicine",
issn = "1073-449X",
publisher = "American Thoracic Society",
number = "3",

}

TY - JOUR

T1 - Association of habitual snoring with glucose and insulin metabolism in nonobese Korean adult men

AU - Shin, Chol

AU - Kim, JinYoung

AU - Kim, Je Hyeong

AU - Lee, Sang Yeub

AU - Shim, Jae Jeong

AU - In, Kwang Ho

AU - Kang, KyungHo

AU - Yoo, SeHwa

AU - Cho, NamHan

AU - Kimm, KuChan

AU - Joo, Soonjae

PY - 2005/2/1

Y1 - 2005/2/1

N2 - Habitual snoring is associated with cardiovascular morbidity and mortality, and metabolic abnormalities such as impaired glucose homeostasis. Many studies were performed in obese Western populations. The purpose of this study was to examine the association of habitual snoring with glucose and insulin metabolism in nonobese Korean men who were free of diabetes and hypertension. A total of 2,719 men ages 40-69 years from the Korean Health and Genome Study participated in this study. Information of snoring frequency was obtained by a questionnaire and glucose and insulin levels during oral glucose tolerance test were measured. Repeated measures analysis of variance detected significant differences in the changing patterns of glucose and insulin levels at 1 hour and 2 hours between habitual snorers and nonhabitual snorers, whereas there were no significant differences in fasting blood glucose and insulin levels. Multivariate logistic regression analyses revealed that habitual snoring was independently associated with elevated 1-hour and 2-hour glucose levels and a 2-hour insulin level, respectively. The present data suggest that habitual snoring may affect glucose-insulin metabolism, independent of diabetes and hypertension, even in nonobese Korean middle-age men. Further prospective studies are needed to examine the causal relationship between habitual snoring and insulin resistance or glucose intolerance.

AB - Habitual snoring is associated with cardiovascular morbidity and mortality, and metabolic abnormalities such as impaired glucose homeostasis. Many studies were performed in obese Western populations. The purpose of this study was to examine the association of habitual snoring with glucose and insulin metabolism in nonobese Korean men who were free of diabetes and hypertension. A total of 2,719 men ages 40-69 years from the Korean Health and Genome Study participated in this study. Information of snoring frequency was obtained by a questionnaire and glucose and insulin levels during oral glucose tolerance test were measured. Repeated measures analysis of variance detected significant differences in the changing patterns of glucose and insulin levels at 1 hour and 2 hours between habitual snorers and nonhabitual snorers, whereas there were no significant differences in fasting blood glucose and insulin levels. Multivariate logistic regression analyses revealed that habitual snoring was independently associated with elevated 1-hour and 2-hour glucose levels and a 2-hour insulin level, respectively. The present data suggest that habitual snoring may affect glucose-insulin metabolism, independent of diabetes and hypertension, even in nonobese Korean middle-age men. Further prospective studies are needed to examine the causal relationship between habitual snoring and insulin resistance or glucose intolerance.

KW - Epidemiology

KW - Glucose tolerance

KW - Insulin resistance

KW - Sleep-disordered breathing

UR - http://www.scopus.com/inward/record.url?scp=19944434111&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=19944434111&partnerID=8YFLogxK

U2 - 10.1164/rccm.200407-906OC

DO - 10.1164/rccm.200407-906OC

M3 - Article

C2 - 15542791

AN - SCOPUS:19944434111

VL - 171

SP - 287

EP - 291

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

SN - 1073-449X

IS - 3

ER -