Association of IOP with systemic factors in a Korean cohort

Yang Jae Kim, Yeoun Sook Chun, Mi Yeon Lee, Joon Mo Kim, Seong Hee Shim, Chungkwon Yoo, Jeong Hun Bae, Ki Ho Park

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose. To assess the relationship of intraocular pressure (IOP) to age, sex, and other demographic and health characteristics in a Korean cohort. Methods. This retrospective cross-sectional study included subjects (n = 155,198) without glaucoma. All participants underwent health screening at the Kangbuk Samsung Hospital from August 2012 to July 2013. Anthropometric measurements, systemic health characteristics, and ocular examination including noncontact tonometry were performed on all participants. Additionally, sociodemographic and behavioral questionnaires were obtained. The systemic variables were analyzed by multiple regression analysis to identify their relationship with IOP. Results. The mean IOP tended to be highest in subjects in their 50s and lowest in subjects in their 20s and 60s for both Korean men and women. This pattern remained the same after adjusting for several demographic and health characteristics. The mean IOP for men was significantly higher than that for women (p G 0.001), but the difference between sexes decreased with increasing age. In the univariate analysis, almost all systemic factors showed a positive association with IOP except for high-density lipoprotein cholesterol. By multiple regression analysis, IOP was positively associated with sex (male), current smoking status, systolic blood pressure, fasting plasma glucose, body mass index, total cholesterol, and high-density lipoprotein (p e 0.001). Conclusions. In a Korean cohort, the mean IOP was highest in subjects in their 50s. The mean IOP for men was significantly higher than that for women. Several systemic factors were significantly correlated with IOP.

Original languageEnglish
Pages (from-to)1182-1188
Number of pages7
JournalOptometry and Vision Science
Volume92
Issue number12
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Intraocular Pressure
Health
HDL Cholesterol
Regression Analysis
Demography
Blood Pressure
Manometry
Sex Characteristics
Glaucoma
Fasting
Body Mass Index
Cross-Sectional Studies
Smoking
Glucose

Keywords

  • age
  • intraocular pressure
  • Korean
  • systemic health characteristics

ASJC Scopus subject areas

  • Ophthalmology
  • Optometry

Cite this

Kim, Y. J., Chun, Y. S., Lee, M. Y., Kim, J. M., Shim, S. H., Yoo, C., ... Park, K. H. (2015). Association of IOP with systemic factors in a Korean cohort. Optometry and Vision Science, 92(12), 1182-1188. https://doi.org/10.1097/OPX.0000000000000722

Association of IOP with systemic factors in a Korean cohort. / Kim, Yang Jae; Chun, Yeoun Sook; Lee, Mi Yeon; Kim, Joon Mo; Shim, Seong Hee; Yoo, Chungkwon; Bae, Jeong Hun; Park, Ki Ho.

In: Optometry and Vision Science, Vol. 92, No. 12, 01.01.2015, p. 1182-1188.

Research output: Contribution to journalArticle

Kim, YJ, Chun, YS, Lee, MY, Kim, JM, Shim, SH, Yoo, C, Bae, JH & Park, KH 2015, 'Association of IOP with systemic factors in a Korean cohort', Optometry and Vision Science, vol. 92, no. 12, pp. 1182-1188. https://doi.org/10.1097/OPX.0000000000000722
Kim, Yang Jae ; Chun, Yeoun Sook ; Lee, Mi Yeon ; Kim, Joon Mo ; Shim, Seong Hee ; Yoo, Chungkwon ; Bae, Jeong Hun ; Park, Ki Ho. / Association of IOP with systemic factors in a Korean cohort. In: Optometry and Vision Science. 2015 ; Vol. 92, No. 12. pp. 1182-1188.
@article{7b98eb2aff9e469ca05337bbd310fdfe,
title = "Association of IOP with systemic factors in a Korean cohort",
abstract = "Purpose. To assess the relationship of intraocular pressure (IOP) to age, sex, and other demographic and health characteristics in a Korean cohort. Methods. This retrospective cross-sectional study included subjects (n = 155,198) without glaucoma. All participants underwent health screening at the Kangbuk Samsung Hospital from August 2012 to July 2013. Anthropometric measurements, systemic health characteristics, and ocular examination including noncontact tonometry were performed on all participants. Additionally, sociodemographic and behavioral questionnaires were obtained. The systemic variables were analyzed by multiple regression analysis to identify their relationship with IOP. Results. The mean IOP tended to be highest in subjects in their 50s and lowest in subjects in their 20s and 60s for both Korean men and women. This pattern remained the same after adjusting for several demographic and health characteristics. The mean IOP for men was significantly higher than that for women (p G 0.001), but the difference between sexes decreased with increasing age. In the univariate analysis, almost all systemic factors showed a positive association with IOP except for high-density lipoprotein cholesterol. By multiple regression analysis, IOP was positively associated with sex (male), current smoking status, systolic blood pressure, fasting plasma glucose, body mass index, total cholesterol, and high-density lipoprotein (p e 0.001). Conclusions. In a Korean cohort, the mean IOP was highest in subjects in their 50s. The mean IOP for men was significantly higher than that for women. Several systemic factors were significantly correlated with IOP.",
keywords = "age, intraocular pressure, Korean, systemic health characteristics",
author = "Kim, {Yang Jae} and Chun, {Yeoun Sook} and Lee, {Mi Yeon} and Kim, {Joon Mo} and Shim, {Seong Hee} and Chungkwon Yoo and Bae, {Jeong Hun} and Park, {Ki Ho}",
year = "2015",
month = "1",
day = "1",
doi = "10.1097/OPX.0000000000000722",
language = "English",
volume = "92",
pages = "1182--1188",
journal = "Optometry and Vision Science",
issn = "1040-5488",
publisher = "Lippincott Williams and Wilkins",
number = "12",

}

TY - JOUR

T1 - Association of IOP with systemic factors in a Korean cohort

AU - Kim, Yang Jae

AU - Chun, Yeoun Sook

AU - Lee, Mi Yeon

AU - Kim, Joon Mo

AU - Shim, Seong Hee

AU - Yoo, Chungkwon

AU - Bae, Jeong Hun

AU - Park, Ki Ho

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Purpose. To assess the relationship of intraocular pressure (IOP) to age, sex, and other demographic and health characteristics in a Korean cohort. Methods. This retrospective cross-sectional study included subjects (n = 155,198) without glaucoma. All participants underwent health screening at the Kangbuk Samsung Hospital from August 2012 to July 2013. Anthropometric measurements, systemic health characteristics, and ocular examination including noncontact tonometry were performed on all participants. Additionally, sociodemographic and behavioral questionnaires were obtained. The systemic variables were analyzed by multiple regression analysis to identify their relationship with IOP. Results. The mean IOP tended to be highest in subjects in their 50s and lowest in subjects in their 20s and 60s for both Korean men and women. This pattern remained the same after adjusting for several demographic and health characteristics. The mean IOP for men was significantly higher than that for women (p G 0.001), but the difference between sexes decreased with increasing age. In the univariate analysis, almost all systemic factors showed a positive association with IOP except for high-density lipoprotein cholesterol. By multiple regression analysis, IOP was positively associated with sex (male), current smoking status, systolic blood pressure, fasting plasma glucose, body mass index, total cholesterol, and high-density lipoprotein (p e 0.001). Conclusions. In a Korean cohort, the mean IOP was highest in subjects in their 50s. The mean IOP for men was significantly higher than that for women. Several systemic factors were significantly correlated with IOP.

AB - Purpose. To assess the relationship of intraocular pressure (IOP) to age, sex, and other demographic and health characteristics in a Korean cohort. Methods. This retrospective cross-sectional study included subjects (n = 155,198) without glaucoma. All participants underwent health screening at the Kangbuk Samsung Hospital from August 2012 to July 2013. Anthropometric measurements, systemic health characteristics, and ocular examination including noncontact tonometry were performed on all participants. Additionally, sociodemographic and behavioral questionnaires were obtained. The systemic variables were analyzed by multiple regression analysis to identify their relationship with IOP. Results. The mean IOP tended to be highest in subjects in their 50s and lowest in subjects in their 20s and 60s for both Korean men and women. This pattern remained the same after adjusting for several demographic and health characteristics. The mean IOP for men was significantly higher than that for women (p G 0.001), but the difference between sexes decreased with increasing age. In the univariate analysis, almost all systemic factors showed a positive association with IOP except for high-density lipoprotein cholesterol. By multiple regression analysis, IOP was positively associated with sex (male), current smoking status, systolic blood pressure, fasting plasma glucose, body mass index, total cholesterol, and high-density lipoprotein (p e 0.001). Conclusions. In a Korean cohort, the mean IOP was highest in subjects in their 50s. The mean IOP for men was significantly higher than that for women. Several systemic factors were significantly correlated with IOP.

KW - age

KW - intraocular pressure

KW - Korean

KW - systemic health characteristics

UR - http://www.scopus.com/inward/record.url?scp=84948570853&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84948570853&partnerID=8YFLogxK

U2 - 10.1097/OPX.0000000000000722

DO - 10.1097/OPX.0000000000000722

M3 - Article

C2 - 26421686

AN - SCOPUS:84948570853

VL - 92

SP - 1182

EP - 1188

JO - Optometry and Vision Science

JF - Optometry and Vision Science

SN - 1040-5488

IS - 12

ER -