Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits

K. S. Kim, J. J. Lee, H. Y. Shin, B. H. Choi, Cheol-Koo Lee, J. J. Kim, B. W. Cho, T. H. Kim

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

The aim of this study was to analyse the combined effect of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms on growth and fatness traits in Duroc pigs. No significant interaction was observed between MC4R and HMGA1 for back-fat traits. An additive mode of inheritance of both gene effects was found for average daily gain and lean meat content. Maximum mean differences from combined genotypic effects were over 2 mm for back fat, 70 g/day for average daily gain and 2% for lean meat content. Therefore, utilization of polymorphisms in both MC4R and HMGA1 for marker-assisted selection could result in an economic benefit to the pig industry.

Original languageEnglish
Pages (from-to)419-421
Number of pages3
JournalAnimal Genetics
Volume37
Issue number4
DOIs
Publication statusPublished - 2006 Aug 1

Fingerprint

AT-Hook Motifs
Receptor, Melanocortin, Type 4
lean meat
Swine
Fats
genetic polymorphism
backfat
average daily gain
Meat
receptors
swine
lipids
Growth
Duroc
marker-assisted selection
inheritance (genetics)
Industry
Economics
industry
economics

Keywords

  • Economic traits
  • HMGA1
  • MC4R
  • Pig breeding

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Genetics
  • Genetics(clinical)

Cite this

Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits. / Kim, K. S.; Lee, J. J.; Shin, H. Y.; Choi, B. H.; Lee, Cheol-Koo; Kim, J. J.; Cho, B. W.; Kim, T. H.

In: Animal Genetics, Vol. 37, No. 4, 01.08.2006, p. 419-421.

Research output: Contribution to journalArticle

Kim, K. S. ; Lee, J. J. ; Shin, H. Y. ; Choi, B. H. ; Lee, Cheol-Koo ; Kim, J. J. ; Cho, B. W. ; Kim, T. H. / Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits. In: Animal Genetics. 2006 ; Vol. 37, No. 4. pp. 419-421.
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