Association of metabolic syndrome with white blood cell subtype and red blood cells

Jeong A. Kim, Youn Seon Choi, Jeong Ik Hong, Su Hyun Kim, Hoe Hyun Jung, Seon Mee Kim

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

Inflammation and thrombogenesis have been suggested as possible causes for cardiovascular events in patients suffering from metabolic syndrome (MS). The primary objective of this study was to determine the relationship between red blood cell (RBC) or white blood cell (WBC) subtypes and MS. The secondary objective was to reveal any gender differences inherent to this association. Body mass index (BMI), blood pressure, serum high-density lipoprotein cholesterol, triglycerides, and glucose were measured. The numbers of WBC subtypes and RBCs were determined in healthy adults. In male subjects, the numbers of total leukocytes, neutrophils, and lymphocytes was elevated in the MS patients (P<0.05). In the male subjects, the numbers of total leukocytes, neutrophils, and lymphocytes were elevated in accordance with the metabolic component count (P<0.05). RBC, monocyte, eosinophil, and basophil counts did not differ in accordance with metabolic component counts (r = 0.406, r = 0.304, r = 0.366; P<0.05). In the female subjects, we determined there to be no differences in the numbers of RBC and WBC subtypes in the MS patients, in accordance with metabolic component counts. The numbers of total leukocytes, neutrophils, and lymphocytes were elevated in the male MS subjects in this study, and these counts increased in accordance with the metabolic component counts. In the female subjects in this study, we determined there to be no association between RBC and WBC subtype counts with MS.

Original languageEnglish
Pages (from-to)133-139
Number of pages7
JournalEndocrine Journal
Volume53
Issue number1
DOIs
Publication statusPublished - 2006

Keywords

  • Lymphocyte
  • Metabolic syndrome
  • Neutrophil
  • Red blood cell
  • White blood cell

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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