Association of periodontitis with urinary albumin excretion in Korean adults with diabetes the 2012 korea national health and nutrition examination survey

Kyungdo Han, Ga Eun Nam, Do-Hoon Kim, Jun Beom Park, Youngkyung Ko, Yong Kyun Roh, Kyung-Hwan Cho, Yong Gyu Park

Research output: Contribution to journalArticle

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Abstract

Albuminuria and periodontitis are both commonly associated with systemic inflammation. However, the association between urinary albumin excretion (UAE) and periodontitis in patients with type 2 diabetes has not been fully investigated. This study aimed to investigate the association between UAE and periodontitis in Korean adults with type 2 diabetes. This study performed a cross-sectional analysis and used hierarchical multivariable logistic regression analysis models. Data from the 2012 Korean National Health and Nutrition Examination Survey were analyzed. A total of 547 patients, with type 2 diabetes without renal impairment, were included in this study. UAE was assessed using the urinary albumin to creatinine ratio (UACR). A community periodontal index greater than or equal to code 3 was used to define periodontitis. The risk of periodontitis tended to increase as UACR increased even after adjustment for potential confounders (P for trend in the odds ratios=0.05 in model 1; 0.02 in model 2; and 0.01 in model 3). In a subgroup analysis, the prevalence of periodontitis was significantly higher in the patients with albuminuria (UACR 30 mg/g) than in those without albuminuria among patients younger than 65 years (P=0.03), those with newly diagnosed diabetes (P=0.04), or those without obesity (P=.04). UAE was positively associated with the risk of periodontitis in Korean adults with type 2 diabetes. In the patients who were younger, were newly diagnosed with diabetes, or had normal body mass index, individuals with albuminuria were more likely to have a higher prevalence of periodontitis. Early identification of periodontitis may be helpful in Korean diabetic adults with increased UAE.

Original languageEnglish
Pages (from-to)e1839
JournalMedicine (United States)
Volume94
Issue number42
DOIs
Publication statusPublished - 2015 Oct 1
Externally publishedYes

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Nutrition Surveys
Periodontitis
Korea
Albumins
Albuminuria
Type 2 Diabetes Mellitus
Creatinine
Periodontal Index
Body Mass Index
Obesity
Cross-Sectional Studies
Logistic Models
Odds Ratio
Regression Analysis
Inflammation
Kidney

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Association of periodontitis with urinary albumin excretion in Korean adults with diabetes the 2012 korea national health and nutrition examination survey. / Han, Kyungdo; Nam, Ga Eun; Kim, Do-Hoon; Park, Jun Beom; Ko, Youngkyung; Roh, Yong Kyun; Cho, Kyung-Hwan; Park, Yong Gyu.

In: Medicine (United States), Vol. 94, No. 42, 01.10.2015, p. e1839.

Research output: Contribution to journalArticle

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