Abstract
Objectives: Sasang constitutional types (SCTs) are four distinct classifications of people based on physiologic and physical characteristics. The different types have been reported to have different disease susceptibility, but there are no studies reporting the association of SCT and hypertension (HTN) over a long-term follow-up period. This study prospectively investigated the association between SCT and incidence of HTN. Design: This was a prospective study in a population-based cohort study in Korea. Subjects: Data from two independent population-based cohorts that are embedded within the Korean Genome and Epidemiology Study were used. A total of 2083 subjects who were free of HTN at baseline were selected for the analysis. Outcome measures: HTN was diagnosed as systolic blood pressure (BP) ≥140 mmHg and diastolic BP ≥90 mmHg, use of antihypertensive medication, or diagnosis by doctor. The SCTs were classified using an integrated diagnostic method that included facial features, body shape, voice, and questionnaire responses. The association between the SCT and the incidence of HTN was investigated by Cox proportional hazard regression analysis and calculation of estimated survival functions. Results: The Tae-eum (TE) type showed a significantly increased risk for HTN (hazard ratio [HR] = 1.55, 95% confidence interval [CI] 1.15-2.10; p = 0.005), even after adjusting for all possible confounders. In a stratified analysis by body mass index (BMI) conducted only in the TE type, even those in the TE type with normal BMI had a significantly higher risk for HTN (HR = 1.47, 95% CI 1.07-2.03; p = 0.016). Furthermore, survival analysis showed that the TE type had a higher rate of developing HTN than the So-eum and So-yang types had, regardless of obesity status. Conclusions: These results show that the TE type is an independent risk factor for HTN. Thus, early prevention and treatment for HTN in this type are needed.
| Original language | English |
|---|---|
| Pages (from-to) | 706-712 |
| Number of pages | 7 |
| Journal | Journal of Alternative and Complementary Medicine |
| Volume | 22 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2016 Sep 1 |
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ASJC Scopus subject areas
- Complementary and alternative medicine
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Association of Sasang Constitutional Types with Incident Hypertension : A 12-Year Follow-Up Study. / Lee, Seung Ku; Yoon, Dae Wui; Lee, Si Woo; Kim, Jong Yeol; Kim, Jin Kwan; Cho, Nam Han; Shin, Chol.
In: Journal of Alternative and Complementary Medicine, Vol. 22, No. 9, 01.09.2016, p. 706-712.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Association of Sasang Constitutional Types with Incident Hypertension
T2 - A 12-Year Follow-Up Study
AU - Lee, Seung Ku
AU - Yoon, Dae Wui
AU - Lee, Si Woo
AU - Kim, Jong Yeol
AU - Kim, Jin Kwan
AU - Cho, Nam Han
AU - Shin, Chol
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Objectives: Sasang constitutional types (SCTs) are four distinct classifications of people based on physiologic and physical characteristics. The different types have been reported to have different disease susceptibility, but there are no studies reporting the association of SCT and hypertension (HTN) over a long-term follow-up period. This study prospectively investigated the association between SCT and incidence of HTN. Design: This was a prospective study in a population-based cohort study in Korea. Subjects: Data from two independent population-based cohorts that are embedded within the Korean Genome and Epidemiology Study were used. A total of 2083 subjects who were free of HTN at baseline were selected for the analysis. Outcome measures: HTN was diagnosed as systolic blood pressure (BP) ≥140 mmHg and diastolic BP ≥90 mmHg, use of antihypertensive medication, or diagnosis by doctor. The SCTs were classified using an integrated diagnostic method that included facial features, body shape, voice, and questionnaire responses. The association between the SCT and the incidence of HTN was investigated by Cox proportional hazard regression analysis and calculation of estimated survival functions. Results: The Tae-eum (TE) type showed a significantly increased risk for HTN (hazard ratio [HR] = 1.55, 95% confidence interval [CI] 1.15-2.10; p = 0.005), even after adjusting for all possible confounders. In a stratified analysis by body mass index (BMI) conducted only in the TE type, even those in the TE type with normal BMI had a significantly higher risk for HTN (HR = 1.47, 95% CI 1.07-2.03; p = 0.016). Furthermore, survival analysis showed that the TE type had a higher rate of developing HTN than the So-eum and So-yang types had, regardless of obesity status. Conclusions: These results show that the TE type is an independent risk factor for HTN. Thus, early prevention and treatment for HTN in this type are needed.
AB - Objectives: Sasang constitutional types (SCTs) are four distinct classifications of people based on physiologic and physical characteristics. The different types have been reported to have different disease susceptibility, but there are no studies reporting the association of SCT and hypertension (HTN) over a long-term follow-up period. This study prospectively investigated the association between SCT and incidence of HTN. Design: This was a prospective study in a population-based cohort study in Korea. Subjects: Data from two independent population-based cohorts that are embedded within the Korean Genome and Epidemiology Study were used. A total of 2083 subjects who were free of HTN at baseline were selected for the analysis. Outcome measures: HTN was diagnosed as systolic blood pressure (BP) ≥140 mmHg and diastolic BP ≥90 mmHg, use of antihypertensive medication, or diagnosis by doctor. The SCTs were classified using an integrated diagnostic method that included facial features, body shape, voice, and questionnaire responses. The association between the SCT and the incidence of HTN was investigated by Cox proportional hazard regression analysis and calculation of estimated survival functions. Results: The Tae-eum (TE) type showed a significantly increased risk for HTN (hazard ratio [HR] = 1.55, 95% confidence interval [CI] 1.15-2.10; p = 0.005), even after adjusting for all possible confounders. In a stratified analysis by body mass index (BMI) conducted only in the TE type, even those in the TE type with normal BMI had a significantly higher risk for HTN (HR = 1.47, 95% CI 1.07-2.03; p = 0.016). Furthermore, survival analysis showed that the TE type had a higher rate of developing HTN than the So-eum and So-yang types had, regardless of obesity status. Conclusions: These results show that the TE type is an independent risk factor for HTN. Thus, early prevention and treatment for HTN in this type are needed.
UR - http://www.scopus.com/inward/record.url?scp=84987817706&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84987817706&partnerID=8YFLogxK
U2 - 10.1089/acm.2015.0052
DO - 10.1089/acm.2015.0052
M3 - Review article
C2 - 27454325
AN - SCOPUS:84987817706
VL - 22
SP - 706
EP - 712
JO - Journal of Alternative and Complementary Medicine
JF - Journal of Alternative and Complementary Medicine
SN - 1075-5535
IS - 9
ER -