Asterias pectinifera-Derived Collagen Peptides Mixed with Halocynthia roretzi Extracts Exhibit Anti-Photoaging Activities during Exposure to UV Irradiation, and Antibacterial Properties

Soo Jin Oh, Ji Ye Park, Bada Won, Yong Taek Oh, Seung Chan Yang, Ok Sarah Shin

Research output: Contribution to journalArticlepeer-review

Abstract

Asterias pectinifera, a species of starfish and cause of concern in the aquaculture industry, was recently identified as a source of non-toxic and highly water-soluble collagen peptides. In this study, we investigated the antioxidant and anti-photoaging functions of compounds formulated using collagen peptides from extracts of Asterias pectinifera and Halocynthia roretzi (AH). Our results showed that AH compounds have various skin protective functions, including antioxidant effects, determined by measuring the scavenging activity of 2,2-diphenyl-1-picrylhydrazyl radicals, as well as anti-melanogenic effects, determined by measuring tyrosinase inhibition activity. To determine whether ethosome-encapsulated AH compounds (E(AH)) exert ultraviolet (UV)-protective effects, human dermal fibroblasts or keratinocytes were incubated with E(AH) before and after exposure to UVA or UVB. E(AH) treatment led to inhibition of photoaging-induced secretion of matrix metalloproteinase-1 and interleukin-6 and -8, which are associated with inflammatory responses during UV irradiation. Finally, the antibacterial effects of AH and E(AH) were confirmed against both gram-negative and gram-positive bacteria. Our results indicate that E(AH) has the potential for use in the development of cosmetics with a range of skin protective functions.

Original languageEnglish
Pages (from-to)1382-1389
Number of pages8
JournalJournal of microbiology and biotechnology
Volume32
Issue number11
DOIs
Publication statusPublished - 2022 Nov 28

Keywords

  • Asterias pectinifera-derived collagen peptides mixed with Halocynthia roretzi extracts (AH)
  • Ethosome-encapsulated AH (E(AH))
  • anti-inflammatory
  • anti-photoaging
  • antibacterial
  • antioxidant

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

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