Asymmetric transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives: synthesis of (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine

Do Min Lee, Jong Cheol Lee, Nakcheol Jeong, Kee In Lee

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Catalytic transfer hydrogenation of 2-tosyloxy-1-(4-hydroxyphenyl)ethanone derivatives leads to efficient synthesis of β-adrenergic agonists, (R)-tembamide, (R)-aegeline, (R)-octopamine, and (R)-denopamine.

Original languageEnglish
Pages (from-to)2662-2667
Number of pages6
JournalTetrahedron Asymmetry
Volume18
Issue number22
DOIs
Publication statusPublished - 2007 Nov 12

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Organic Chemistry
  • Materials Chemistry
  • Drug Discovery

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