Available therapies and current management of fibromyalgia: Fcusing on pharmacological agents

Changsu Han, S. J. Lee, S. Y. Lee, H. J. Seo, S. M. Wang, M. H. Park, A. A. Patkar, J. Koh, P. S. Masand, Chi Un Pae

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Fibromyalgia (FM) is a chronic medical condition characterized by physical, psychiatric and psychological symptoms. Widespread pain, fatigue, sleep disturbances, heightened sensitivity, morning stiffness, decreased volition, depressed mood and a history of early abuse are frequently reported by patients with FM. Treatment of fibromyalgia is multidisciplinary, with an emphasis on active patient participation, medications, cognitive-behavioral therapy and physical modalities. No single medication has yet been found to sufficiently control all the symptoms of FM; currently available medication classes include antidepressants, nonsteroidal anti-inflammatory drugs, opioids, sedatives, muscle relaxants, analgesics, hypnotic agents and anticonvulsants. Hence, treatment for patients with FM, including pharmacological and non-pharmacological approaches, should be individualized based on each patient's clinical history, target symptoms and functional impairments. Although nonpharmacological modalities are also frequently used, recent research has focused on identifying more effective pharmacological treatments, particularly antidepressants and anticonvulsants. Furthermore, several new pharmacological agents have been now officially approved for the treatment of patients with FM. Thus, the purpose of this review is to help healthcare professionals make informed decisions about the appropriate use of a number of pharmacological treatments for patients with FM.

Original languageEnglish
Pages (from-to)539-557
Number of pages19
JournalDrugs of Today
Volume47
Issue number7
DOIs
Publication statusPublished - 2011 Jul 1

Fingerprint

Fibromyalgia
Pharmacology
Hypnotics and Sedatives
Anticonvulsants
Therapeutics
Antidepressive Agents
Patient Participation
Cognitive Therapy
Opioid Analgesics
Fatigue
Psychiatry
Analgesics
Sleep
Anti-Inflammatory Agents
Psychology
Delivery of Health Care
Pain
Muscles
Research
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Han, C., Lee, S. J., Lee, S. Y., Seo, H. J., Wang, S. M., Park, M. H., ... Pae, C. U. (2011). Available therapies and current management of fibromyalgia: Fcusing on pharmacological agents. Drugs of Today, 47(7), 539-557. https://doi.org/10.1358/dot.2011.47.7.1603503

Available therapies and current management of fibromyalgia : Fcusing on pharmacological agents. / Han, Changsu; Lee, S. J.; Lee, S. Y.; Seo, H. J.; Wang, S. M.; Park, M. H.; Patkar, A. A.; Koh, J.; Masand, P. S.; Pae, Chi Un.

In: Drugs of Today, Vol. 47, No. 7, 01.07.2011, p. 539-557.

Research output: Contribution to journalReview article

Han, C, Lee, SJ, Lee, SY, Seo, HJ, Wang, SM, Park, MH, Patkar, AA, Koh, J, Masand, PS & Pae, CU 2011, 'Available therapies and current management of fibromyalgia: Fcusing on pharmacological agents', Drugs of Today, vol. 47, no. 7, pp. 539-557. https://doi.org/10.1358/dot.2011.47.7.1603503
Han, Changsu ; Lee, S. J. ; Lee, S. Y. ; Seo, H. J. ; Wang, S. M. ; Park, M. H. ; Patkar, A. A. ; Koh, J. ; Masand, P. S. ; Pae, Chi Un. / Available therapies and current management of fibromyalgia : Fcusing on pharmacological agents. In: Drugs of Today. 2011 ; Vol. 47, No. 7. pp. 539-557.
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