Balanced approach can help initial outcomes: Analysis of initial 50 cases of a new liver transplantation program in East Asia

Dong Sik Kim, Young Dong Yu, Sung Won Jung, Kyung Sook Yang, Yeon Seok Seo, Soon Ho Um, Sung Ock Suh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: To evaluate patient triage pattern and outcomes according to types of liver transplantation as part of a new liver transplant program developed in an East Asian country with a limited number of deceased donors. Methods: Medical records of initial 50 liver transplantations were reviewed retrospectively. Results: Twenty-nine patients underwent deceased donor liver transplantation (DDLT) and 21 patients underwent living donor liver transplantation (LDLT). Mean model for end-stage liver disease scores of recipients of DDLT and LDLT were 24.9 ± 11.6 and 13.1 ± 5.4, respectively (P < 0.0001). Twenty-eight patients had HCCs and 17 of them (60.7%) underwent LDLT, which was 80.9% of LDLTs. There were 2 cases of perioperative mortality; each was from DDLT and LDLT, respectively. Median follow-up was 18 months. Overall patient and graft survival rates at 6 months, 1 and 2 years were 95.7%, 93.4%, and 89.8 %, respectively. There was no significant difference in survival between DDLT and LDLT. Overall recurrence-free survival rates of hepatocellular carcinoma (HCC) patients at 6 month, 1, and 2 years were 96.3%, 96.3%, and 90.3%, respectively. There was no significant difference in recurrence-free survival between DDLT and LDLT. Conclusion: As a new liver transplant program with limited resource and waiting list, patients with critical condition could undergo DDLT whereas relatively stable patients with HCCs were mostly directed to LDLT. We recommend a balanced approach between DDLT and LDLT for initiating liver transplant programs.

Original languageEnglish
Pages (from-to)22-27
Number of pages6
JournalAnnals of Surgical Treatment and Research
Volume87
Issue number1
DOIs
Publication statusPublished - 2014 Jul

Keywords

  • Donor selection
  • Liver transplantation
  • Liver transplantation program
  • Outcome
  • Survival

ASJC Scopus subject areas

  • Surgery

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