Abstract
A xanthogranuloma (XG) is a rare benign histiocytic disorder that occurs mostly in infants and young children. Approximately 15% of XGs occur in adults and usually appear as solitary lesions in the head and the neck region. In most cases, an XG appears as a solitary yellow-red cutaneous nodule in the head and the neck region that regresses spontaneously over a course of months to years. An extracutaneous XG is uncommon, and it can occur with or without a cutaneous XG. An extracutaneous XG most commonly occurs in the eye, but findings at other sites such as the central nervous system, lungs, liver, spleen, kidneys, and bone have also been reported. The pathogenesis of XGs is unknown. Although physical and infectious factors have been considered, most investigators postulate that they are caused by a reactive response to an unknown stimulus. Xanthogranulomas can be divided into juvenile and adult forms. Distinctive from the juvenile form, the adult XG rarely undergoes a spontaneous regression, and concomitant extracutaneous examples are very uncommon. Patients with adult XGs are mostly in their late teens to late 30s, although approximately 5% of the patients are in their 60s to 70s. We report an exceptional case of an adult breast XG in a 60-year-old woman.
| Original language | English |
|---|---|
| Pages (from-to) | 535-537 |
| Number of pages | 3 |
| Journal | Journal of Ultrasound in Medicine |
| Volume | 26 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2007 Jan 1 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
Cite this
Bilateral xanthogranuloma of the breast : Radiologic findings and pathologic correlation. / Hwang, Sung Ho; Son, Eun Ju; Oh, Ki Keun; Kim, Eun Kyung; Jung, Joon; Jung, Woo Hee.
In: Journal of Ultrasound in Medicine, Vol. 26, No. 4, 01.01.2007, p. 535-537.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bilateral xanthogranuloma of the breast
T2 - Radiologic findings and pathologic correlation
AU - Hwang, Sung Ho
AU - Son, Eun Ju
AU - Oh, Ki Keun
AU - Kim, Eun Kyung
AU - Jung, Joon
AU - Jung, Woo Hee
PY - 2007/1/1
Y1 - 2007/1/1
N2 - A xanthogranuloma (XG) is a rare benign histiocytic disorder that occurs mostly in infants and young children. Approximately 15% of XGs occur in adults and usually appear as solitary lesions in the head and the neck region. In most cases, an XG appears as a solitary yellow-red cutaneous nodule in the head and the neck region that regresses spontaneously over a course of months to years. An extracutaneous XG is uncommon, and it can occur with or without a cutaneous XG. An extracutaneous XG most commonly occurs in the eye, but findings at other sites such as the central nervous system, lungs, liver, spleen, kidneys, and bone have also been reported. The pathogenesis of XGs is unknown. Although physical and infectious factors have been considered, most investigators postulate that they are caused by a reactive response to an unknown stimulus. Xanthogranulomas can be divided into juvenile and adult forms. Distinctive from the juvenile form, the adult XG rarely undergoes a spontaneous regression, and concomitant extracutaneous examples are very uncommon. Patients with adult XGs are mostly in their late teens to late 30s, although approximately 5% of the patients are in their 60s to 70s. We report an exceptional case of an adult breast XG in a 60-year-old woman.
AB - A xanthogranuloma (XG) is a rare benign histiocytic disorder that occurs mostly in infants and young children. Approximately 15% of XGs occur in adults and usually appear as solitary lesions in the head and the neck region. In most cases, an XG appears as a solitary yellow-red cutaneous nodule in the head and the neck region that regresses spontaneously over a course of months to years. An extracutaneous XG is uncommon, and it can occur with or without a cutaneous XG. An extracutaneous XG most commonly occurs in the eye, but findings at other sites such as the central nervous system, lungs, liver, spleen, kidneys, and bone have also been reported. The pathogenesis of XGs is unknown. Although physical and infectious factors have been considered, most investigators postulate that they are caused by a reactive response to an unknown stimulus. Xanthogranulomas can be divided into juvenile and adult forms. Distinctive from the juvenile form, the adult XG rarely undergoes a spontaneous regression, and concomitant extracutaneous examples are very uncommon. Patients with adult XGs are mostly in their late teens to late 30s, although approximately 5% of the patients are in their 60s to 70s. We report an exceptional case of an adult breast XG in a 60-year-old woman.
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UR - http://www.scopus.com/inward/citedby.url?scp=34047212768&partnerID=8YFLogxK
U2 - 10.7863/jum.2007.26.4.535
DO - 10.7863/jum.2007.26.4.535
M3 - Article
VL - 26
SP - 535
EP - 537
JO - Journal of Ultrasound in Medicine
JF - Journal of Ultrasound in Medicine
SN - 0278-4297
IS - 4
ER -