This study examined the utility of sol-gel-derived bioactive glass microspheres (BGMs) as a reinforcement to improve the mechanical properties and biological performance of poly(eμ-caprolactone) (PCL) polymer. All of the PCL-BGMs composites produced, with a variety of BGMs contents (10, 20, and 30 wt %), showed a uniform distribution of the BGMs in the PCL matrix, particularly owing to their spherical shape and small size. This led to a considerable increase in the elastic modulus from 93 ± 12 MPa to 635 ± 179 MPa with increasing BGMs content from 0 to 30 wt %. Furthermore, the addition of the BGMs to the PCL polymer significantly increased the hydrophilicity of the PCL-BGMs composites, which led to a higher water absorption and degradation rate. The PCL-BGMs composite with a BGMs content of 30 wt % showed vigorous growth of apatite crystals with a high aspect ratio on its surface after soaking in the simulated body fluid for 7 days, resulting in the creation of a porous carbonate hydroxyapatite layer.
|Number of pages||9|
|Journal||Journal of Biomedical Materials Research - Part B Applied Biomaterials|
|Publication status||Published - 2012 May|
- bioactive glass
- mechanical properties
ASJC Scopus subject areas
- Biomedical Engineering