Bioelectrical Impedance Analysis for Evaluation of Donor Hepatic Steatosis in Living-Donor Liver Transplantation

S. Hwang, Young-Dong Yu, G. C. Park, P. J. Park, Y. I. Choi, N. K. Choi, K. W. Kim, G. W. Song, D. H. Jung, J. S. Yun, S. Y. Choi, S. G. Lee

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3 Citations (Scopus)

Abstract

Objective: To assess whether bioelectrical impedance analysis (BIA) can be used to evaluate the degree of hepatic steatosis in potential living liver donors. Material and Methods: From May 2008 to April 2009, BIA was measured in 302 living donor candidates. Correlations among body mass index (BMI; calculated as weight in kilograms divided by height in meters squared), total fatty changes at percutaneous needle liver biopsy, and BIA-derived fat composition were assessed. Results: The median (range) BIA-derived fat proportion was 19.4% (4.8%-35.3%), BMI was 24 (17-39), and hepatic steatosis at liver biopsy was 2% (0%-75%). Crude correlations were observed between BIA-derived fat proportion and hepatic steatosis (r2 = 0.14; P = .000), between BMI and hepatic steatosis (r2 = 0.27; P = .000), and between BMI and BIA-derived fat proportion (r2 = .25; P = .000). Receiver operating characteristic curve analysis revealed that the area under the curve of BIA-derived fat proportion was smaller than that of BMI, and no significant cutoff value was identified. Conclusions: These results suggest that BIA-derived fat composition alone cannot be used to accurately determine the degree of hepatic steatosis. However, a combination of BMI and BIA-derived fat composition may increase clinical ability to assess hepatic steatosis.

Original languageEnglish
Pages (from-to)1492-1496
Number of pages5
JournalTransplantation Proceedings
Volume42
Issue number5
DOIs
Publication statusPublished - 2010 Jun 1
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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    Hwang, S., Yu, Y-D., Park, G. C., Park, P. J., Choi, Y. I., Choi, N. K., Kim, K. W., Song, G. W., Jung, D. H., Yun, J. S., Choi, S. Y., & Lee, S. G. (2010). Bioelectrical Impedance Analysis for Evaluation of Donor Hepatic Steatosis in Living-Donor Liver Transplantation. Transplantation Proceedings, 42(5), 1492-1496. https://doi.org/10.1016/j.transproceed.2010.03.137