Biologically Safe, Degradable Self-Destruction System for On-Demand, Programmable Transient Electronics

Jeong Woong Shin; Jong Chan Choe; Joong Hoon Lee; Won Bae Han; Tae Min Jang; Gwan Jin Ko; Seung Min Yang; Yu Gyeong Kim; Jaesun Joo; Bong Hee Lim; Eunkyoung Park; Suk Won Hwang

doi:10.1021/acsnano.1c05463

Biologically Safe, Degradable Self-Destruction System for On-Demand, Programmable Transient Electronics

Jeong Woong Shin, Jong Chan Choe, Joong Hoon Lee, Won Bae Han, Tae Min Jang, Gwan Jin Ko, Seung Min Yang, Yu Gyeong Kim, Jaesun Joo, Bong Hee Lim, Eunkyoung Park, Suk Won Hwang

KU-KIST Graduate School of Converging Science and Technology

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The lifetime of transient electronic components can be programmed via the use of encapsulation/passivation layers or of on-demand, stimuli-responsive polymers (heat, light, or chemicals), but yet most research is limited to slow dissolution rate, hazardous constituents, or byproducts, or complicated synthesis of reactants. Here we present a physicochemical destruction system with dissolvable, nontoxic materials as an efficient, multipurpose platform, where chemically produced bubbles rapidly collapse device structures and acidic molecules accelerate dissolution of functional traces. Extensive studies of composites based on biodegradable polymers (gelatin and poly(lactic-co-glycolic acid)) and harmless blowing agents (organic acid and bicarbonate salt) validate the capability for the desired system. Integration with wearable/recyclable electronic components, fast-degradable device layouts, and wireless microfluidic devices highlights potential applicability toward versatile/multifunctional transient systems. In vivo toxicity tests demonstrate biological safety of the proposed system.

Original language	English
Pages (from-to)	19310-19320
Number of pages	11
Journal	ACS nano
Volume	15
Issue number	12
DOIs	https://doi.org/10.1021/acsnano.1c05463
Publication status	Published - 2021 Dec 28

Keywords

biodegradable
biosafe
self-destruction
transient electronics
triggering

ASJC Scopus subject areas

Materials Science(all)
Engineering(all)
Physics and Astronomy(all)

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10.1021/acsnano.1c05463

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@article{984a4cd74d9c4566b22fe83ac9c6f3bb,

title = "Biologically Safe, Degradable Self-Destruction System for On-Demand, Programmable Transient Electronics",

abstract = "The lifetime of transient electronic components can be programmed via the use of encapsulation/passivation layers or of on-demand, stimuli-responsive polymers (heat, light, or chemicals), but yet most research is limited to slow dissolution rate, hazardous constituents, or byproducts, or complicated synthesis of reactants. Here we present a physicochemical destruction system with dissolvable, nontoxic materials as an efficient, multipurpose platform, where chemically produced bubbles rapidly collapse device structures and acidic molecules accelerate dissolution of functional traces. Extensive studies of composites based on biodegradable polymers (gelatin and poly(lactic-co-glycolic acid)) and harmless blowing agents (organic acid and bicarbonate salt) validate the capability for the desired system. Integration with wearable/recyclable electronic components, fast-degradable device layouts, and wireless microfluidic devices highlights potential applicability toward versatile/multifunctional transient systems. In vivo toxicity tests demonstrate biological safety of the proposed system.",

keywords = "biodegradable, biosafe, self-destruction, transient electronics, triggering",

author = "Shin, {Jeong Woong} and {Chan Choe}, Jong and Lee, {Joong Hoon} and Han, {Won Bae} and Jang, {Tae Min} and Ko, {Gwan Jin} and Yang, {Seung Min} and Kim, {Yu Gyeong} and Jaesun Joo and Lim, {Bong Hee} and Eunkyoung Park and Hwang, {Suk Won}",

note = "Funding Information: This work was supported by Korea University, KU-KIST Graduate School of Converging Science and Technology Program, Korea Medical Device Development Fund Grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry & Energy, the Ministry of Health & Welfare, and the Ministry of Food and Drug Safety) (202012D30), and National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (grant NRF-2017R1E1A1A01075027). This research was supported by the MSIT(Ministry of Science and ICT), Korea, under the ICT Creative Consilience program (IITP-2021-2020-0-01819) supervised by the IITP (Institute for Information & communications Technology Planning & Evaluation). Publisher Copyright: {\textcopyright} 2021 American Chemical Society.",

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doi = "10.1021/acsnano.1c05463",

language = "English",

volume = "15",

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AU - Shin, Jeong Woong

AU - Chan Choe, Jong

AU - Lee, Joong Hoon

AU - Han, Won Bae

AU - Jang, Tae Min

AU - Ko, Gwan Jin

AU - Yang, Seung Min

AU - Kim, Yu Gyeong

AU - Joo, Jaesun

AU - Lim, Bong Hee

AU - Park, Eunkyoung

AU - Hwang, Suk Won

N1 - Funding Information: This work was supported by Korea University, KU-KIST Graduate School of Converging Science and Technology Program, Korea Medical Device Development Fund Grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry & Energy, the Ministry of Health & Welfare, and the Ministry of Food and Drug Safety) (202012D30), and National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (grant NRF-2017R1E1A1A01075027). This research was supported by the MSIT(Ministry of Science and ICT), Korea, under the ICT Creative Consilience program (IITP-2021-2020-0-01819) supervised by the IITP (Institute for Information & communications Technology Planning & Evaluation). Publisher Copyright: © 2021 American Chemical Society.

PY - 2021/12/28

Y1 - 2021/12/28

N2 - The lifetime of transient electronic components can be programmed via the use of encapsulation/passivation layers or of on-demand, stimuli-responsive polymers (heat, light, or chemicals), but yet most research is limited to slow dissolution rate, hazardous constituents, or byproducts, or complicated synthesis of reactants. Here we present a physicochemical destruction system with dissolvable, nontoxic materials as an efficient, multipurpose platform, where chemically produced bubbles rapidly collapse device structures and acidic molecules accelerate dissolution of functional traces. Extensive studies of composites based on biodegradable polymers (gelatin and poly(lactic-co-glycolic acid)) and harmless blowing agents (organic acid and bicarbonate salt) validate the capability for the desired system. Integration with wearable/recyclable electronic components, fast-degradable device layouts, and wireless microfluidic devices highlights potential applicability toward versatile/multifunctional transient systems. In vivo toxicity tests demonstrate biological safety of the proposed system.

AB - The lifetime of transient electronic components can be programmed via the use of encapsulation/passivation layers or of on-demand, stimuli-responsive polymers (heat, light, or chemicals), but yet most research is limited to slow dissolution rate, hazardous constituents, or byproducts, or complicated synthesis of reactants. Here we present a physicochemical destruction system with dissolvable, nontoxic materials as an efficient, multipurpose platform, where chemically produced bubbles rapidly collapse device structures and acidic molecules accelerate dissolution of functional traces. Extensive studies of composites based on biodegradable polymers (gelatin and poly(lactic-co-glycolic acid)) and harmless blowing agents (organic acid and bicarbonate salt) validate the capability for the desired system. Integration with wearable/recyclable electronic components, fast-degradable device layouts, and wireless microfluidic devices highlights potential applicability toward versatile/multifunctional transient systems. In vivo toxicity tests demonstrate biological safety of the proposed system.

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KW - biosafe

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KW - transient electronics

KW - triggering

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JO - ACS Nano

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ER -

Biologically Safe, Degradable Self-Destruction System for On-Demand, Programmable Transient Electronics

Abstract

Keywords

ASJC Scopus subject areas

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