Biomaterials for the Treatment of Tendon Injury

Sung Eun Kim, Jae Gyoon Kim, Kyeongsoon Park

    Research output: Contribution to journalReview articlepeer-review

    8 Citations (Scopus)

    Abstract

    Background:: Most tendon injuries are occurring from a gradual wearing and tearing of the tendon tissues from overuse. Such injuries are usually seen in sports, exercising, or daily activities that involve a high mechanical load and weight bearing. However, owing to the lack of both cellularity and blood vessels in tendons, the process of tendon repair is slow and inefficient. Although various conservative (non-surgical) and surgical management options are conducted by the clinicians, a gold standard of these approaches does not exist. In this regard, the treatment of tendon injuries is challenging. Method:: Here, we describe the recent advances of biomaterial-based approaches for the treatment of injured tendons. Results:: Regenerative medicine is an emerging multidisciplinary research that specializes in the repair of damaged tendon tissues through the delivery of regenerative factors by biomaterials. Conclusion:: Although current biomaterial-based treatment strategies have shown their potential for tendon healing, future research and clinical applications should focused on finding the optimum combinations of regenerative factors with ideal biomaterials for the repair of tendons.

    Original languageEnglish
    Pages (from-to)467-477
    Number of pages11
    JournalTissue Engineering and Regenerative Medicine
    Volume16
    Issue number5
    DOIs
    Publication statusPublished - 2019 Oct 1

    Keywords

    • Biomaterials
    • Blood vessel
    • Delivery
    • Regenerative factor
    • Tendon healing

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • Biomedical Engineering

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