TY - JOUR
T1 - Biomechanical function of a balloon nucleus pulposus replacement system
T2 - A human cadaveric spine study
AU - Lee, Taekyeong
AU - Lim, Tae Hong
AU - Lee, Sang Heon
AU - Kim, Joo Han
AU - Hong, Junghwa
N1 - Funding Information:
This work was supported by the Korean Ministry of Health and Welfare (KHIDI: HI15C1025), the Korean Small and Medium Business Administration (S2296904), and the Korean Ministry of Trade, Industry & Energy (No.10048732, No. 10060251). We appreciate Professor Juneyoung Lee in College of Medicine, Korea University for his advice about the statistics and Dr. Eunha Oh for her statistical data analyses.
Funding Information:
Grant sponsor: The Ministry of Health & Welfare through the Korea Health Industry Development Institute (KHIDI); Grant number: HI15C1025; Grant sponsor: The Small and Medium Business Administration(SMBA, Korea); Grant number: S2296904; Grant sponsor: The Ministry of Trade, Industry & Energy (MOTIE, Korea); Grant numbers: 10048732, 10060251. Correspondence to: Junghwa Hong, (T: þ82-2-3290-3988; F: þ82-2-922-8154; E-mail: hongjh32@korea.ac.kr)
PY - 2018/1
Y1 - 2018/1
N2 - With recent advances in motion-sparing techniques in spine surgery, disc nucleus replacement (DNR) has been introduced as a viable method to restore the biomechanical functions of the spine. Several methods of DNR have been proposed in the literature. However, the risk of device migration or extrusion is a major issue that should be addressed for a successful DNR. DNR using a balloon nucleus (BN) filled with pressurized fluid may be capable of reducing such risks while preserving the advantages of DNR. The objective of this study was to investigate the biomechanical functionalities of the human cadaveric lumbar motion segments with a custom made BN filled with saline at internal fluid pressure of 0.3 or 0.6 MPa in terms of axial and rotational flexibilities of the L4-L5 motion segment. Axial flexibility was quantified by the axial displacement resulting from an axial compressive force of 400 N while the rotational flexibility by the range of motions determined as the rotational angles in response to a pure moment of 6.0 Nm in flexion, extension, and right- and left-lateral bending directions. These tests were performed successively on the motion segment in the following conditions: intact, post nucleotomy, implanting BN with 0.3 MPa, and BN with 0.6 MPa. The nucleotomy was found to significantly increase both the axial and rotational flexibilities while the implantation of the BN reduced the axial and rotational flexibilities to those of the intact segment. The axial and rotational flexibilities of the segment with the BN with 0.3 MPa were greater than those of the segment with the BN with 0.6 MPa.
AB - With recent advances in motion-sparing techniques in spine surgery, disc nucleus replacement (DNR) has been introduced as a viable method to restore the biomechanical functions of the spine. Several methods of DNR have been proposed in the literature. However, the risk of device migration or extrusion is a major issue that should be addressed for a successful DNR. DNR using a balloon nucleus (BN) filled with pressurized fluid may be capable of reducing such risks while preserving the advantages of DNR. The objective of this study was to investigate the biomechanical functionalities of the human cadaveric lumbar motion segments with a custom made BN filled with saline at internal fluid pressure of 0.3 or 0.6 MPa in terms of axial and rotational flexibilities of the L4-L5 motion segment. Axial flexibility was quantified by the axial displacement resulting from an axial compressive force of 400 N while the rotational flexibility by the range of motions determined as the rotational angles in response to a pure moment of 6.0 Nm in flexion, extension, and right- and left-lateral bending directions. These tests were performed successively on the motion segment in the following conditions: intact, post nucleotomy, implanting BN with 0.3 MPa, and BN with 0.6 MPa. The nucleotomy was found to significantly increase both the axial and rotational flexibilities while the implantation of the BN reduced the axial and rotational flexibilities to those of the intact segment. The axial and rotational flexibilities of the segment with the BN with 0.3 MPa were greater than those of the segment with the BN with 0.6 MPa.
KW - balloon nucleus replacement system
KW - biomechanical functions
KW - disc nucleus replacement
KW - intervertebral disc
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U2 - 10.1002/jor.23607
DO - 10.1002/jor.23607
M3 - Article
C2 - 28513885
AN - SCOPUS:85020786766
VL - 36
SP - 167
EP - 173
JO - Journal of Orthopaedic Research
JF - Journal of Orthopaedic Research
SN - 0736-0266
IS - 1
ER -