Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification

So Yeon Lee; Kyoung Ran Kim; Duhee Bang; Se Won Bae; Hak Joong Kim; Dae Ro Ahn

doi:10.1039/c6bm00296j

Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification

So Yeon Lee, Kyoung Ran Kim, Duhee Bang, Se Won Bae, Hak Joong Kim, Dae Ro Ahn

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Although rolling circle amplification (RCA) is an efficient method to produce DNA materials for biomedical applications, it does not yield nano-sized products suitable for intracellular delivery. We here provide the ways to control the size of RCA products and show a potential application of the size-controlled DNA nanoparticles.

Original language	English
Pages (from-to)	1314-1317
Number of pages	4
Journal	Biomaterials Science
Volume	4
Issue number	9
DOIs	https://doi.org/10.1039/c6bm00296j
Publication status	Published - 2016 Sept

ASJC Scopus subject areas

Biomedical Engineering
Materials Science(all)

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10.1039/c6bm00296j

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title = "Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification",

abstract = "Although rolling circle amplification (RCA) is an efficient method to produce DNA materials for biomedical applications, it does not yield nano-sized products suitable for intracellular delivery. We here provide the ways to control the size of RCA products and show a potential application of the size-controlled DNA nanoparticles.",

author = "Lee, {So Yeon} and Kim, {Kyoung Ran} and Duhee Bang and Bae, {Se Won} and Kim, {Hak Joong} and Ahn, {Dae Ro}",

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AU - Lee, So Yeon

AU - Kim, Kyoung Ran

AU - Bang, Duhee

AU - Bae, Se Won

AU - Kim, Hak Joong

AU - Ahn, Dae Ro

PY - 2016/9

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N2 - Although rolling circle amplification (RCA) is an efficient method to produce DNA materials for biomedical applications, it does not yield nano-sized products suitable for intracellular delivery. We here provide the ways to control the size of RCA products and show a potential application of the size-controlled DNA nanoparticles.

AB - Although rolling circle amplification (RCA) is an efficient method to produce DNA materials for biomedical applications, it does not yield nano-sized products suitable for intracellular delivery. We here provide the ways to control the size of RCA products and show a potential application of the size-controlled DNA nanoparticles.

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DO - 10.1039/c6bm00296j

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EP - 1317

JO - Biomaterials Science

JF - Biomaterials Science

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Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification

Abstract

ASJC Scopus subject areas

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