Bladder and liver involvement of visceral larva migrans may mimic malignancy

Eun Joo Kang, Yoon Ji Choi, Jung Sun Kim, Byung Hyun Lee, Ka Won Kang, Hong Jun Kim, Eun Sang Yu, Yeul Hong Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Visceral larva migrans (VLM) syndrome is a clinical manifestation of systemic organ involvement by Toxocara species. VLM with involvement of the bladder and liver is a rare finding. A 62-year-old woman presented with diffuse bladder wall thickening and multiple liver masses with peripheral eosinophilia and urinary symptoms. We considered malignancy or eosinophilic cystitis through clinical manifestations and imaging findings. However, no suspicious malignant lesions were observed on cystoscopy and liver mass biopsy revealed the presence of eosinophilic necrotizing granuloma without malignant cells. Anti-Toxocara antibodies were detected by western blotting and the patient was diagnosed with VLM syndrome. After taking prednisolone, urinary symptoms disappeared. On abdominal computed tomography scan taken after three months, the size of multiple liver masses and bladder wall thickening had decreased. VLM syndrome should be suspected in patients with an atypical imaging pattern and peripheral eosinophilia.

Original languageEnglish
Pages (from-to)419-424
Number of pages6
JournalCancer Research and Treatment
Volume46
Issue number4
DOIs
Publication statusPublished - 2014 Jan 1

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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