Blue-Red LED wavelength shifting strategy for enhancing beta-carotene production from halotolerant microalga, Dunaliella salina

Sang Il Han, Sok Kim, Changsu Lee, Yoon-E Choi

Research output: Contribution to journalArticle

7 Citations (Scopus)


In the present study, to improve the photosynthetic betacarotene productivity of Dunaliella salina, a blue-red LED wavelength-shifting system (B-R system) was investigated. Dunaliella salina under the B-R system showed enhanced density and beta-carotene productivity compared to D. salina cultivated under single light-emitting diode light wavelengths (blue, white, and red light-emitting diode). Additionally, we developed blue light-adapted D. salina (ALE-D. salina) using an adaptive laboratory evolution (ALE) approach. In combination with the B-R system applied to ALE-D. salina (ALE B-R system), the beta-carotene concentration (33.94 ± 0.52 μM) was enhanced by 19.7% compared to that observed for the non-ALE-treated wild-type of D. salina (intact D. salina) under the B-R system (28.34 ± 0.24 μM).

Original languageEnglish
Pages (from-to)101-106
Number of pages6
JournalJournal of Microbiology
Issue number2
Publication statusPublished - 2019 Feb 1



  • adaptive laboratory evolution
  • beta-carotene
  • Dunaliella salina
  • light-emitting diode
  • wavelength shift

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology

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