Abstract
Aim To investigate the body fat distribution in Korean women with polycystic ovary syndrome (PCOS) and the association of those distribution with metabolic parameters and hormone profiles. Methods A total 90 patients with PCOS and 97 women without PCOS (control group) were included in this study. Total body fat, abdominal visceral fat, and subcutaneous fat were determined on abdominal fat computed tomography. Lipid profiles and sex-hormone binding globulin (SHBG), testosterone, free androgen index (FAI), and cortisol were measured in PCOS group. Results Total body fat and body fat distribution in the PCOS group were not significantly different from the control group in Korean women (P=0.054, P=0.761, P=0.104), but abdominal visceral to subcutaneous fat ratio was larger in the PCOS group than the control group (P=0.047). Not only total body fat and visceral fat, but also subcutaneous fat in the PCOS group had a positive correlation with homeostatic model assessment-insulin resistance, fasting blood sugar, low-density lipoprotein cholesterol, triglyceride, systolic blood pressure, diastolic blood pressure, fasting insulin, free testosterone, FAI, body mass index, but negative correlation with SHBG and high-density lipoprotein cholesterol. Conclusions Korean PCOS women had the same body fat distribution as the control group. Subcutaneous fat was also correlated with metabolic parameters and hormone profiles in the Korean PCOS group.
| Original language | English |
|---|---|
| Pages (from-to) | 1577-1583 |
| Number of pages | 7 |
| Journal | Journal of Obstetrics and Gynaecology Research |
| Volume | 41 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2015 Jan 1 |
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Keywords
- abdominal fat computed tomography
- fat distribution
- insulin resistance
- Korean
- polycystic ovary syndrome
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Body fat distribution and its associated factors in Korean women with polycystic ovary syndrome. / Jin, Chan Hee; Yuk, Jin Sung; Choi, Kyung Mook; Yi, Kyong Wook; Kim, Tak; Hur, Jun Young; Shin, Jung-Ho.
In: Journal of Obstetrics and Gynaecology Research, Vol. 41, No. 10, 01.01.2015, p. 1577-1583.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Body fat distribution and its associated factors in Korean women with polycystic ovary syndrome
AU - Jin, Chan Hee
AU - Yuk, Jin Sung
AU - Choi, Kyung Mook
AU - Yi, Kyong Wook
AU - Kim, Tak
AU - Hur, Jun Young
AU - Shin, Jung-Ho
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Aim To investigate the body fat distribution in Korean women with polycystic ovary syndrome (PCOS) and the association of those distribution with metabolic parameters and hormone profiles. Methods A total 90 patients with PCOS and 97 women without PCOS (control group) were included in this study. Total body fat, abdominal visceral fat, and subcutaneous fat were determined on abdominal fat computed tomography. Lipid profiles and sex-hormone binding globulin (SHBG), testosterone, free androgen index (FAI), and cortisol were measured in PCOS group. Results Total body fat and body fat distribution in the PCOS group were not significantly different from the control group in Korean women (P=0.054, P=0.761, P=0.104), but abdominal visceral to subcutaneous fat ratio was larger in the PCOS group than the control group (P=0.047). Not only total body fat and visceral fat, but also subcutaneous fat in the PCOS group had a positive correlation with homeostatic model assessment-insulin resistance, fasting blood sugar, low-density lipoprotein cholesterol, triglyceride, systolic blood pressure, diastolic blood pressure, fasting insulin, free testosterone, FAI, body mass index, but negative correlation with SHBG and high-density lipoprotein cholesterol. Conclusions Korean PCOS women had the same body fat distribution as the control group. Subcutaneous fat was also correlated with metabolic parameters and hormone profiles in the Korean PCOS group.
AB - Aim To investigate the body fat distribution in Korean women with polycystic ovary syndrome (PCOS) and the association of those distribution with metabolic parameters and hormone profiles. Methods A total 90 patients with PCOS and 97 women without PCOS (control group) were included in this study. Total body fat, abdominal visceral fat, and subcutaneous fat were determined on abdominal fat computed tomography. Lipid profiles and sex-hormone binding globulin (SHBG), testosterone, free androgen index (FAI), and cortisol were measured in PCOS group. Results Total body fat and body fat distribution in the PCOS group were not significantly different from the control group in Korean women (P=0.054, P=0.761, P=0.104), but abdominal visceral to subcutaneous fat ratio was larger in the PCOS group than the control group (P=0.047). Not only total body fat and visceral fat, but also subcutaneous fat in the PCOS group had a positive correlation with homeostatic model assessment-insulin resistance, fasting blood sugar, low-density lipoprotein cholesterol, triglyceride, systolic blood pressure, diastolic blood pressure, fasting insulin, free testosterone, FAI, body mass index, but negative correlation with SHBG and high-density lipoprotein cholesterol. Conclusions Korean PCOS women had the same body fat distribution as the control group. Subcutaneous fat was also correlated with metabolic parameters and hormone profiles in the Korean PCOS group.
KW - abdominal fat computed tomography
KW - fat distribution
KW - insulin resistance
KW - Korean
KW - polycystic ovary syndrome
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U2 - 10.1111/jog.12767
DO - 10.1111/jog.12767
M3 - Article
VL - 41
SP - 1577
EP - 1583
JO - Journal of Obstetrics and Gynaecology Research
JF - Journal of Obstetrics and Gynaecology Research
SN - 1341-8076
IS - 10
ER -