Body mass index and mortality in Korean intensive care units

A prospective multicenter cohort study

So Yeon Lim, Won Il Choi, Kyeongman Jeon, Eliseo Guallar, Younsuck Koh, Chae Man Lim, Shin Ok Koh, Sungwon Na, Young Joo Lee, Seok Chan Kim, Ick Hee Kim, Je Hyeong Kim, Jae Yeol Kim, Jaemin Lim, Chin Kook Rhee, Sunghoon Park, Ho Cheol Kim, Jin Hwa Lee, Jisook Park, Gee Young Suh & 8 others Chi Min Park, Jin Won Huh, Suk Kyung Hong, Kwang Joo Park, Chan Kwon Park, Gyu Rak Chon, Ji Hyun Lee, Jae Hwa Cho

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: The level of body mass index (BMI) that is associated with the lowest mortality in critically ill patients in Asian populations is uncertain. We aimed to examine the association of BMI with hospital mortality in critically ill patients in Korea. Methods: We conducted a prospective multicenter cohort study of 3,655 critically ill patients in 22 intensive care units (ICUs) in Korea. BMI was categorized into five groups: <18.5, 18.5 to 22.9, 23.0 to 24.9 (the reference category), 25.0 to 29.9, and ≥30.0 kg/m2. Results: The median BMI was 22.6 (IQR 20.3 to 25.1). The percentages of patients with BMI<18.5, 18.5 to 22.9, 23.0 to 24.9, 25.0 to 29.9, and ≥30.0 were 12, 42.3, 19.9, 22.4, and 3.3%, respectively. The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend (p = 0.02). Conclusions: A graded inverse association between BMI and hospital mortality with a strong significant trend was found in critically ill patients in Korea.

Original languageEnglish
Article numbere90039
JournalPLoS One
Volume9
Issue number4
DOIs
Publication statusPublished - 2014 Apr 18

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Intensive care units
cohort studies
Multicenter Studies
Intensive Care Units
body mass index
Body Mass Index
Cohort Studies
Mortality
Critical Illness
Korea
Hospital Mortality
Korean Peninsula
Hazards
Population

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Lim, S. Y., Choi, W. I., Jeon, K., Guallar, E., Koh, Y., Lim, C. M., ... Cho, J. H. (2014). Body mass index and mortality in Korean intensive care units: A prospective multicenter cohort study. PLoS One, 9(4), [e90039]. https://doi.org/10.1371/journal.pone.0090039

Body mass index and mortality in Korean intensive care units : A prospective multicenter cohort study. / Lim, So Yeon; Choi, Won Il; Jeon, Kyeongman; Guallar, Eliseo; Koh, Younsuck; Lim, Chae Man; Koh, Shin Ok; Na, Sungwon; Lee, Young Joo; Kim, Seok Chan; Kim, Ick Hee; Kim, Je Hyeong; Kim, Jae Yeol; Lim, Jaemin; Rhee, Chin Kook; Park, Sunghoon; Kim, Ho Cheol; Lee, Jin Hwa; Park, Jisook; Suh, Gee Young; Park, Chi Min; Huh, Jin Won; Hong, Suk Kyung; Park, Kwang Joo; Park, Chan Kwon; Chon, Gyu Rak; Lee, Ji Hyun; Cho, Jae Hwa.

In: PLoS One, Vol. 9, No. 4, e90039, 18.04.2014.

Research output: Contribution to journalArticle

Lim, SY, Choi, WI, Jeon, K, Guallar, E, Koh, Y, Lim, CM, Koh, SO, Na, S, Lee, YJ, Kim, SC, Kim, IH, Kim, JH, Kim, JY, Lim, J, Rhee, CK, Park, S, Kim, HC, Lee, JH, Park, J, Suh, GY, Park, CM, Huh, JW, Hong, SK, Park, KJ, Park, CK, Chon, GR, Lee, JH & Cho, JH 2014, 'Body mass index and mortality in Korean intensive care units: A prospective multicenter cohort study', PLoS One, vol. 9, no. 4, e90039. https://doi.org/10.1371/journal.pone.0090039
Lim, So Yeon ; Choi, Won Il ; Jeon, Kyeongman ; Guallar, Eliseo ; Koh, Younsuck ; Lim, Chae Man ; Koh, Shin Ok ; Na, Sungwon ; Lee, Young Joo ; Kim, Seok Chan ; Kim, Ick Hee ; Kim, Je Hyeong ; Kim, Jae Yeol ; Lim, Jaemin ; Rhee, Chin Kook ; Park, Sunghoon ; Kim, Ho Cheol ; Lee, Jin Hwa ; Park, Jisook ; Suh, Gee Young ; Park, Chi Min ; Huh, Jin Won ; Hong, Suk Kyung ; Park, Kwang Joo ; Park, Chan Kwon ; Chon, Gyu Rak ; Lee, Ji Hyun ; Cho, Jae Hwa. / Body mass index and mortality in Korean intensive care units : A prospective multicenter cohort study. In: PLoS One. 2014 ; Vol. 9, No. 4.
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T1 - Body mass index and mortality in Korean intensive care units

T2 - A prospective multicenter cohort study

AU - Lim, So Yeon

AU - Choi, Won Il

AU - Jeon, Kyeongman

AU - Guallar, Eliseo

AU - Koh, Younsuck

AU - Lim, Chae Man

AU - Koh, Shin Ok

AU - Na, Sungwon

AU - Lee, Young Joo

AU - Kim, Seok Chan

AU - Kim, Ick Hee

AU - Kim, Je Hyeong

AU - Kim, Jae Yeol

AU - Lim, Jaemin

AU - Rhee, Chin Kook

AU - Park, Sunghoon

AU - Kim, Ho Cheol

AU - Lee, Jin Hwa

AU - Park, Jisook

AU - Suh, Gee Young

AU - Park, Chi Min

AU - Huh, Jin Won

AU - Hong, Suk Kyung

AU - Park, Kwang Joo

AU - Park, Chan Kwon

AU - Chon, Gyu Rak

AU - Lee, Ji Hyun

AU - Cho, Jae Hwa

PY - 2014/4/18

Y1 - 2014/4/18

N2 - Background: The level of body mass index (BMI) that is associated with the lowest mortality in critically ill patients in Asian populations is uncertain. We aimed to examine the association of BMI with hospital mortality in critically ill patients in Korea. Methods: We conducted a prospective multicenter cohort study of 3,655 critically ill patients in 22 intensive care units (ICUs) in Korea. BMI was categorized into five groups: <18.5, 18.5 to 22.9, 23.0 to 24.9 (the reference category), 25.0 to 29.9, and ≥30.0 kg/m2. Results: The median BMI was 22.6 (IQR 20.3 to 25.1). The percentages of patients with BMI<18.5, 18.5 to 22.9, 23.0 to 24.9, 25.0 to 29.9, and ≥30.0 were 12, 42.3, 19.9, 22.4, and 3.3%, respectively. The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend (p = 0.02). Conclusions: A graded inverse association between BMI and hospital mortality with a strong significant trend was found in critically ill patients in Korea.

AB - Background: The level of body mass index (BMI) that is associated with the lowest mortality in critically ill patients in Asian populations is uncertain. We aimed to examine the association of BMI with hospital mortality in critically ill patients in Korea. Methods: We conducted a prospective multicenter cohort study of 3,655 critically ill patients in 22 intensive care units (ICUs) in Korea. BMI was categorized into five groups: <18.5, 18.5 to 22.9, 23.0 to 24.9 (the reference category), 25.0 to 29.9, and ≥30.0 kg/m2. Results: The median BMI was 22.6 (IQR 20.3 to 25.1). The percentages of patients with BMI<18.5, 18.5 to 22.9, 23.0 to 24.9, 25.0 to 29.9, and ≥30.0 were 12, 42.3, 19.9, 22.4, and 3.3%, respectively. The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend (p = 0.02). Conclusions: A graded inverse association between BMI and hospital mortality with a strong significant trend was found in critically ill patients in Korea.

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