Body mass index and mortality in Korean intensive care units: A prospective multicenter cohort study

So Yeon Lim, Won Il Choi, Kyeongman Jeon, Eliseo Guallar, Younsuck Koh, Chae Man Lim, Shin Ok Koh, Sungwon Na, Young Joo Lee, Seok Chan Kim, Ick Hee Kim, Je Hyeong Kim, Jae Yeol Kim, Jaemin Lim, Chin Kook Rhee, Sunghoon Park, Ho Cheol Kim, Jin Hwa Lee, Jisook Park, Gee Young SuhChi Min Park, Jin Won Huh, Suk Kyung Hong, Kwang Joo Park, Chan Kwon Park, Gyu Rak Chon, Ji Hyun Lee, Jae Hwa Cho

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7 Citations (Scopus)

Abstract

Background: The level of body mass index (BMI) that is associated with the lowest mortality in critically ill patients in Asian populations is uncertain. We aimed to examine the association of BMI with hospital mortality in critically ill patients in Korea. Methods: We conducted a prospective multicenter cohort study of 3,655 critically ill patients in 22 intensive care units (ICUs) in Korea. BMI was categorized into five groups: <18.5, 18.5 to 22.9, 23.0 to 24.9 (the reference category), 25.0 to 29.9, and ≥30.0 kg/m2. Results: The median BMI was 22.6 (IQR 20.3 to 25.1). The percentages of patients with BMI<18.5, 18.5 to 22.9, 23.0 to 24.9, 25.0 to 29.9, and ≥30.0 were 12, 42.3, 19.9, 22.4, and 3.3%, respectively. The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend (p = 0.02). Conclusions: A graded inverse association between BMI and hospital mortality with a strong significant trend was found in critically ill patients in Korea.

Original languageEnglish
Article numbere90039
JournalPloS one
Volume9
Issue number4
DOIs
Publication statusPublished - 2014 Apr 18

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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    Lim, S. Y., Choi, W. I., Jeon, K., Guallar, E., Koh, Y., Lim, C. M., Koh, S. O., Na, S., Lee, Y. J., Kim, S. C., Kim, I. H., Kim, J. H., Kim, J. Y., Lim, J., Rhee, C. K., Park, S., Kim, H. C., Lee, J. H., Park, J., ... Cho, J. H. (2014). Body mass index and mortality in Korean intensive care units: A prospective multicenter cohort study. PloS one, 9(4), [e90039]. https://doi.org/10.1371/journal.pone.0090039