Bone scan appearance of renal osteodystrophy in diabetic chronic renal failure patients

Y. So, Young Hyun In Young Hyun, Soo Lee Dong Soo Lee, C. Ahn, J. K. Chung, S. Kim, Chul Lee Myung Chul Lee, Sang Lee Jung Sang Lee, C. S. Koh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

To investigate Tc-99m methylenediphosphonate (MDP) bone scan appearance in diabetic chronic renal failure patients, we compared the bone scan images of chronic renal failure patients with and without diabetes. The number of patients studied was 134, of whom 43 had diabetes. Two nuclear medicine physicians read Tc-99m MDP bone scan images and for six areas - the axial skeleton, long bone, skull and mandible, periarticular areas, costochondral junction, and sternum - assigned a score of either 1 or 0. The sums of scores were compared. We also performed multivariate analysis including sex, age, and serum creatinine level using analysis of covariance. DM group patients scored significantly lower (2.01 ± 0.95) than those of the non-DM group (3.26 ± 1.16). Analysis of covariance revealed that the lower DM group score was independent of sex, age, and serum creatinine level. The bone scans of diabetic chronic renal failure patients showed less Tc-99m MDP uptake than those of non-diabetic patients. Thus, diagnosing renal osteodystrophy in diabetic chronic renal failure patients on bone scan images could be difficult.

Original languageEnglish
Pages (from-to)417-421
Number of pages5
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Volume16
Issue number6
Publication statusPublished - 1998
Externally publishedYes

Keywords

  • Bone scan
  • Diabetes mellitus
  • Renal osteodystrophy
  • Tc-99m methylenediphosphonate

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology

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  • Cite this

    So, Y., In Young Hyun, Y. H., Dong Soo Lee, S. L., Ahn, C., Chung, J. K., Kim, S., Myung Chul Lee, C. L., Jung Sang Lee, S. L., & Koh, C. S. (1998). Bone scan appearance of renal osteodystrophy in diabetic chronic renal failure patients. Radiation Medicine - Medical Imaging and Radiation Oncology, 16(6), 417-421.