Abstract
In plants, the steroidal hormone brassinosteroid (BR) regulates numerous developmental processes, including photomorphogenesis. Genetic, proteomic, and genomic studies in Arabidopsis have illustrated a fully connected BR signal transduction pathway from the cell surface receptor kinase BRI1 to the BZR1 family of transcription factors. Genome-wide analyses of protein-DNA interactions have identified thousands of BZR1 target genes that link BR signaling to various cellular, metabolic, and developmental processes, as well as other signaling pathways. In controlling photomorphogenesis, BR signaling is highly integrated with the light, gibberellin, and auxin pathways through both direct interactions between signaling proteins and transcriptional regulation of key components of these pathways. BR signaling also cross talks with other receptor kinase pathways to modulate stomata development and innate immunity. The molecular connections in the BR signaling network demonstrate a robust steroid signaling system that has evolved in plants to orchestrate signal transduction, genome expression, metabolism, defense, and development.
| Original language | English |
|---|---|
| Pages (from-to) | 701-724 |
| Number of pages | 24 |
| Journal | Annual Review of Genetics |
| Volume | 46 |
| DOIs | |
| Publication status | Published - 2012 Dec 3 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Genetics
Cite this
Brassinosteroid signaling network and regulation of photomorphogenesis. / Wang, Zhi Yong; Bai, Ming Yi; Oh, Eunkyoo; Zhu, Jia Ying.
In: Annual Review of Genetics, Vol. 46, 03.12.2012, p. 701-724.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Brassinosteroid signaling network and regulation of photomorphogenesis
AU - Wang, Zhi Yong
AU - Bai, Ming Yi
AU - Oh, Eunkyoo
AU - Zhu, Jia Ying
PY - 2012/12/3
Y1 - 2012/12/3
N2 - In plants, the steroidal hormone brassinosteroid (BR) regulates numerous developmental processes, including photomorphogenesis. Genetic, proteomic, and genomic studies in Arabidopsis have illustrated a fully connected BR signal transduction pathway from the cell surface receptor kinase BRI1 to the BZR1 family of transcription factors. Genome-wide analyses of protein-DNA interactions have identified thousands of BZR1 target genes that link BR signaling to various cellular, metabolic, and developmental processes, as well as other signaling pathways. In controlling photomorphogenesis, BR signaling is highly integrated with the light, gibberellin, and auxin pathways through both direct interactions between signaling proteins and transcriptional regulation of key components of these pathways. BR signaling also cross talks with other receptor kinase pathways to modulate stomata development and innate immunity. The molecular connections in the BR signaling network demonstrate a robust steroid signaling system that has evolved in plants to orchestrate signal transduction, genome expression, metabolism, defense, and development.
AB - In plants, the steroidal hormone brassinosteroid (BR) regulates numerous developmental processes, including photomorphogenesis. Genetic, proteomic, and genomic studies in Arabidopsis have illustrated a fully connected BR signal transduction pathway from the cell surface receptor kinase BRI1 to the BZR1 family of transcription factors. Genome-wide analyses of protein-DNA interactions have identified thousands of BZR1 target genes that link BR signaling to various cellular, metabolic, and developmental processes, as well as other signaling pathways. In controlling photomorphogenesis, BR signaling is highly integrated with the light, gibberellin, and auxin pathways through both direct interactions between signaling proteins and transcriptional regulation of key components of these pathways. BR signaling also cross talks with other receptor kinase pathways to modulate stomata development and innate immunity. The molecular connections in the BR signaling network demonstrate a robust steroid signaling system that has evolved in plants to orchestrate signal transduction, genome expression, metabolism, defense, and development.
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UR - http://www.scopus.com/inward/citedby.url?scp=84870217274&partnerID=8YFLogxK
U2 - 10.1146/annurev-genet-102209-163450
DO - 10.1146/annurev-genet-102209-163450
M3 - Article
VL - 46
SP - 701
EP - 724
JO - Annual Review of Genetics
JF - Annual Review of Genetics
SN - 0066-4197
ER -