Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990-2013

Findings from the Global Burden of Disease Study 2013

Maziar Moradi-Lakeh, Mohammad H. Forouzanfar, Stein Emil Vollset, Charbel El Bcheraoui, Farah Daoud, Ashkan Afshin, Raghid Charara, Ibrahim Khalil, Hideki Higashi, Mohamed Magdy Abd El Razek, Aliasghar Ahmad Kiadaliri, Khurshid Alam, Nadia Akseer, Nawal Al-Hamad, Raghib Ali, Mohammad Abdulaziz Almazroa, Mahmoud A. Alomari, Abdullah A. Al-Rabeeah, Ubai Alsharif, Khalid A. Altirkawi & 74 others Suleman Atique, Alaa Badawi, Lope H. Barrero, Mohammed Basulaiman, Shahrzad Bazargan-Hejazi, Neeraj Bedi, Isabela M. Bensenor, Rachelle Buchbinder, Hadi Danawi, Samath D. Dharmaratne, Faiez Zannad, Maryam S. Farvid, Seyed Mohammad Fereshtehnejad, Farshad Farzadfar, Florian Fischer, Rahul Gupta, Randah Ribhi Hamadeh, Samer Hamidi, Masako Horino, Damian G. Hoy, Mohamed Hsairi, Abdullatif Husseini, Mehdi Javanbakht, Jost B. Jonas, Amir Kasaeian, Ejaz Ahmad Khan, Jagdish Khubchandani, Ann Kristin Knudsen, Jacek A. Kopec, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Azeem Majeed, Reza Malekzadeh, Kedar Mate, Alem Mehari, Michele Meltzer, Ziad A. Memish, Mojde Mirarefin, Shafiu Mohammed, Aliya Naheed, Carla Makhlouf Obermeyer, In Hwan Oh, Eun Kee Park, Emmanuel Kwame Peprah, Farshad Pourmalek, Mostafa Qorbani, Anwar Rafay, Vafa Rahimi-Movaghar, Rahman Shiri, Sajjad Ur Rahman, Rajesh Kumar Rai, Saleem M. Rana, Sadaf G. Sepanlou, Masood Ali Shaikh, Ivy Shiue, Abla Mehio Sibai, Diego Augusto Santos Silva, Jasvinder A. Singh, Jens Christoffer Skogen, Abdullah Sulieman Terkawi, Kingsley N. Ukwaja, Ronny Westerman, Naohiro Yonemoto, Seok-Jun Yoon, Mustafa Z. Younis, Zoubida Zaidi, Maysaa El Sayed Zaki, Stephen S. Lim, Haidong Wang, Theo Vos, Mohsen Naghavi, Alan D. Lopez, Christopher J.L. Murray, Ali H. Mokdad

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objectives We used findings from the Global Burden of Disease Study 2013 to report the burden of musculoskeletal disorders in the Eastern Mediterranean Region (EMR). Methods The burden of musculoskeletal disorders was calculated for the EMR's 22 countries between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, death, years of live lost, years lived with disability and disability-adjusted life years (DALYs). Results For musculoskeletal disorders, the crude DALYs rate per 100 000 increased from 1297.1 (95% uncertainty interval (UI) 924.3-1703.4) in 1990 to 1606.0 (95% UI 1141.2-2130.4) in 2013. During 1990-2013, the total DALYs of musculoskeletal disorders increased by 105.2% in the EMR compared with a 58.0% increase in the rest of the world. The burden of musculoskeletal disorders as a proportion of total DALYs increased from 2.4% (95% UI 1.7-3.0) in 1990 to 4.7% (95% UI 3.6-5.8) in 2013. The range of point prevalence (per 1000) among the EMR countries was 28.2-136.0 for low back pain, 27.3-49.7 for neck pain, 9.7-37.3 for osteoarthritis (OA), 0.6-2.2 for rheumatoid arthritis and 0.1-0.8 for gout. Low back pain and neck pain had the highest burden in EMR countries. Conclusions This study shows a high burden of musculoskeletal disorders, with a faster increase in EMR compared with the rest of the world. The reasons for this faster increase need to be explored. Our findings call for incorporating prevention and control programmes that should include improving health data, addressing risk factors, providing evidence-based care and community programmes to increase awareness.

Original languageEnglish
Pages (from-to)1365-1373
Number of pages9
JournalAnnals of the Rheumatic Diseases
Volume76
Issue number8
DOIs
Publication statusPublished - 2017 Aug 1

Fingerprint

Mediterranean Region
Quality-Adjusted Life Years
Uncertainty
Neck Pain
Low Back Pain
Gout
Osteoarthritis
Health
Rheumatoid Arthritis
Global Burden of Disease
Morbidity
Mortality

Keywords

  • Epidemiology
  • Gout
  • Low Back Pain
  • Osteoarthritis
  • Rheumatoid Arthritis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990-2013 : Findings from the Global Burden of Disease Study 2013. / Moradi-Lakeh, Maziar; Forouzanfar, Mohammad H.; Vollset, Stein Emil; El Bcheraoui, Charbel; Daoud, Farah; Afshin, Ashkan; Charara, Raghid; Khalil, Ibrahim; Higashi, Hideki; Abd El Razek, Mohamed Magdy; Kiadaliri, Aliasghar Ahmad; Alam, Khurshid; Akseer, Nadia; Al-Hamad, Nawal; Ali, Raghib; Almazroa, Mohammad Abdulaziz; Alomari, Mahmoud A.; Al-Rabeeah, Abdullah A.; Alsharif, Ubai; Altirkawi, Khalid A.; Atique, Suleman; Badawi, Alaa; Barrero, Lope H.; Basulaiman, Mohammed; Bazargan-Hejazi, Shahrzad; Bedi, Neeraj; Bensenor, Isabela M.; Buchbinder, Rachelle; Danawi, Hadi; Dharmaratne, Samath D.; Zannad, Faiez; Farvid, Maryam S.; Fereshtehnejad, Seyed Mohammad; Farzadfar, Farshad; Fischer, Florian; Gupta, Rahul; Hamadeh, Randah Ribhi; Hamidi, Samer; Horino, Masako; Hoy, Damian G.; Hsairi, Mohamed; Husseini, Abdullatif; Javanbakht, Mehdi; Jonas, Jost B.; Kasaeian, Amir; Khan, Ejaz Ahmad; Khubchandani, Jagdish; Knudsen, Ann Kristin; Kopec, Jacek A.; Lunevicius, Raimundas; Abd El Razek, Hassan Magdy; Majeed, Azeem; Malekzadeh, Reza; Mate, Kedar; Mehari, Alem; Meltzer, Michele; Memish, Ziad A.; Mirarefin, Mojde; Mohammed, Shafiu; Naheed, Aliya; Obermeyer, Carla Makhlouf; Oh, In Hwan; Park, Eun Kee; Peprah, Emmanuel Kwame; Pourmalek, Farshad; Qorbani, Mostafa; Rafay, Anwar; Rahimi-Movaghar, Vafa; Shiri, Rahman; Rahman, Sajjad Ur; Rai, Rajesh Kumar; Rana, Saleem M.; Sepanlou, Sadaf G.; Shaikh, Masood Ali; Shiue, Ivy; Sibai, Abla Mehio; Silva, Diego Augusto Santos; Singh, Jasvinder A.; Skogen, Jens Christoffer; Terkawi, Abdullah Sulieman; Ukwaja, Kingsley N.; Westerman, Ronny; Yonemoto, Naohiro; Yoon, Seok-Jun; Younis, Mustafa Z.; Zaidi, Zoubida; Zaki, Maysaa El Sayed; Lim, Stephen S.; Wang, Haidong; Vos, Theo; Naghavi, Mohsen; Lopez, Alan D.; Murray, Christopher J.L.; Mokdad, Ali H.

In: Annals of the Rheumatic Diseases, Vol. 76, No. 8, 01.08.2017, p. 1365-1373.

Research output: Contribution to journalArticle

Moradi-Lakeh, M, Forouzanfar, MH, Vollset, SE, El Bcheraoui, C, Daoud, F, Afshin, A, Charara, R, Khalil, I, Higashi, H, Abd El Razek, MM, Kiadaliri, AA, Alam, K, Akseer, N, Al-Hamad, N, Ali, R, Almazroa, MA, Alomari, MA, Al-Rabeeah, AA, Alsharif, U, Altirkawi, KA, Atique, S, Badawi, A, Barrero, LH, Basulaiman, M, Bazargan-Hejazi, S, Bedi, N, Bensenor, IM, Buchbinder, R, Danawi, H, Dharmaratne, SD, Zannad, F, Farvid, MS, Fereshtehnejad, SM, Farzadfar, F, Fischer, F, Gupta, R, Hamadeh, RR, Hamidi, S, Horino, M, Hoy, DG, Hsairi, M, Husseini, A, Javanbakht, M, Jonas, JB, Kasaeian, A, Khan, EA, Khubchandani, J, Knudsen, AK, Kopec, JA, Lunevicius, R, Abd El Razek, HM, Majeed, A, Malekzadeh, R, Mate, K, Mehari, A, Meltzer, M, Memish, ZA, Mirarefin, M, Mohammed, S, Naheed, A, Obermeyer, CM, Oh, IH, Park, EK, Peprah, EK, Pourmalek, F, Qorbani, M, Rafay, A, Rahimi-Movaghar, V, Shiri, R, Rahman, SU, Rai, RK, Rana, SM, Sepanlou, SG, Shaikh, MA, Shiue, I, Sibai, AM, Silva, DAS, Singh, JA, Skogen, JC, Terkawi, AS, Ukwaja, KN, Westerman, R, Yonemoto, N, Yoon, S-J, Younis, MZ, Zaidi, Z, Zaki, MES, Lim, SS, Wang, H, Vos, T, Naghavi, M, Lopez, AD, Murray, CJL & Mokdad, AH 2017, 'Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990-2013: Findings from the Global Burden of Disease Study 2013', Annals of the Rheumatic Diseases, vol. 76, no. 8, pp. 1365-1373. https://doi.org/10.1136/annrheumdis-2016-210146
Moradi-Lakeh, Maziar ; Forouzanfar, Mohammad H. ; Vollset, Stein Emil ; El Bcheraoui, Charbel ; Daoud, Farah ; Afshin, Ashkan ; Charara, Raghid ; Khalil, Ibrahim ; Higashi, Hideki ; Abd El Razek, Mohamed Magdy ; Kiadaliri, Aliasghar Ahmad ; Alam, Khurshid ; Akseer, Nadia ; Al-Hamad, Nawal ; Ali, Raghib ; Almazroa, Mohammad Abdulaziz ; Alomari, Mahmoud A. ; Al-Rabeeah, Abdullah A. ; Alsharif, Ubai ; Altirkawi, Khalid A. ; Atique, Suleman ; Badawi, Alaa ; Barrero, Lope H. ; Basulaiman, Mohammed ; Bazargan-Hejazi, Shahrzad ; Bedi, Neeraj ; Bensenor, Isabela M. ; Buchbinder, Rachelle ; Danawi, Hadi ; Dharmaratne, Samath D. ; Zannad, Faiez ; Farvid, Maryam S. ; Fereshtehnejad, Seyed Mohammad ; Farzadfar, Farshad ; Fischer, Florian ; Gupta, Rahul ; Hamadeh, Randah Ribhi ; Hamidi, Samer ; Horino, Masako ; Hoy, Damian G. ; Hsairi, Mohamed ; Husseini, Abdullatif ; Javanbakht, Mehdi ; Jonas, Jost B. ; Kasaeian, Amir ; Khan, Ejaz Ahmad ; Khubchandani, Jagdish ; Knudsen, Ann Kristin ; Kopec, Jacek A. ; Lunevicius, Raimundas ; Abd El Razek, Hassan Magdy ; Majeed, Azeem ; Malekzadeh, Reza ; Mate, Kedar ; Mehari, Alem ; Meltzer, Michele ; Memish, Ziad A. ; Mirarefin, Mojde ; Mohammed, Shafiu ; Naheed, Aliya ; Obermeyer, Carla Makhlouf ; Oh, In Hwan ; Park, Eun Kee ; Peprah, Emmanuel Kwame ; Pourmalek, Farshad ; Qorbani, Mostafa ; Rafay, Anwar ; Rahimi-Movaghar, Vafa ; Shiri, Rahman ; Rahman, Sajjad Ur ; Rai, Rajesh Kumar ; Rana, Saleem M. ; Sepanlou, Sadaf G. ; Shaikh, Masood Ali ; Shiue, Ivy ; Sibai, Abla Mehio ; Silva, Diego Augusto Santos ; Singh, Jasvinder A. ; Skogen, Jens Christoffer ; Terkawi, Abdullah Sulieman ; Ukwaja, Kingsley N. ; Westerman, Ronny ; Yonemoto, Naohiro ; Yoon, Seok-Jun ; Younis, Mustafa Z. ; Zaidi, Zoubida ; Zaki, Maysaa El Sayed ; Lim, Stephen S. ; Wang, Haidong ; Vos, Theo ; Naghavi, Mohsen ; Lopez, Alan D. ; Murray, Christopher J.L. ; Mokdad, Ali H. / Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990-2013 : Findings from the Global Burden of Disease Study 2013. In: Annals of the Rheumatic Diseases. 2017 ; Vol. 76, No. 8. pp. 1365-1373.
@article{1b1d169df7314fb38d203525670240b1,
title = "Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990-2013: Findings from the Global Burden of Disease Study 2013",
abstract = "Objectives We used findings from the Global Burden of Disease Study 2013 to report the burden of musculoskeletal disorders in the Eastern Mediterranean Region (EMR). Methods The burden of musculoskeletal disorders was calculated for the EMR's 22 countries between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, death, years of live lost, years lived with disability and disability-adjusted life years (DALYs). Results For musculoskeletal disorders, the crude DALYs rate per 100 000 increased from 1297.1 (95{\%} uncertainty interval (UI) 924.3-1703.4) in 1990 to 1606.0 (95{\%} UI 1141.2-2130.4) in 2013. During 1990-2013, the total DALYs of musculoskeletal disorders increased by 105.2{\%} in the EMR compared with a 58.0{\%} increase in the rest of the world. The burden of musculoskeletal disorders as a proportion of total DALYs increased from 2.4{\%} (95{\%} UI 1.7-3.0) in 1990 to 4.7{\%} (95{\%} UI 3.6-5.8) in 2013. The range of point prevalence (per 1000) among the EMR countries was 28.2-136.0 for low back pain, 27.3-49.7 for neck pain, 9.7-37.3 for osteoarthritis (OA), 0.6-2.2 for rheumatoid arthritis and 0.1-0.8 for gout. Low back pain and neck pain had the highest burden in EMR countries. Conclusions This study shows a high burden of musculoskeletal disorders, with a faster increase in EMR compared with the rest of the world. The reasons for this faster increase need to be explored. Our findings call for incorporating prevention and control programmes that should include improving health data, addressing risk factors, providing evidence-based care and community programmes to increase awareness.",
keywords = "Epidemiology, Gout, Low Back Pain, Osteoarthritis, Rheumatoid Arthritis",
author = "Maziar Moradi-Lakeh and Forouzanfar, {Mohammad H.} and Vollset, {Stein Emil} and {El Bcheraoui}, Charbel and Farah Daoud and Ashkan Afshin and Raghid Charara and Ibrahim Khalil and Hideki Higashi and {Abd El Razek}, {Mohamed Magdy} and Kiadaliri, {Aliasghar Ahmad} and Khurshid Alam and Nadia Akseer and Nawal Al-Hamad and Raghib Ali and Almazroa, {Mohammad Abdulaziz} and Alomari, {Mahmoud A.} and Al-Rabeeah, {Abdullah A.} and Ubai Alsharif and Altirkawi, {Khalid A.} and Suleman Atique and Alaa Badawi and Barrero, {Lope H.} and Mohammed Basulaiman and Shahrzad Bazargan-Hejazi and Neeraj Bedi and Bensenor, {Isabela M.} and Rachelle Buchbinder and Hadi Danawi and Dharmaratne, {Samath D.} and Faiez Zannad and Farvid, {Maryam S.} and Fereshtehnejad, {Seyed Mohammad} and Farshad Farzadfar and Florian Fischer and Rahul Gupta and Hamadeh, {Randah Ribhi} and Samer Hamidi and Masako Horino and Hoy, {Damian G.} and Mohamed Hsairi and Abdullatif Husseini and Mehdi Javanbakht and Jonas, {Jost B.} and Amir Kasaeian and Khan, {Ejaz Ahmad} and Jagdish Khubchandani and Knudsen, {Ann Kristin} and Kopec, {Jacek A.} and Raimundas Lunevicius and {Abd El Razek}, {Hassan Magdy} and Azeem Majeed and Reza Malekzadeh and Kedar Mate and Alem Mehari and Michele Meltzer and Memish, {Ziad A.} and Mojde Mirarefin and Shafiu Mohammed and Aliya Naheed and Obermeyer, {Carla Makhlouf} and Oh, {In Hwan} and Park, {Eun Kee} and Peprah, {Emmanuel Kwame} and Farshad Pourmalek and Mostafa Qorbani and Anwar Rafay and Vafa Rahimi-Movaghar and Rahman Shiri and Rahman, {Sajjad Ur} and Rai, {Rajesh Kumar} and Rana, {Saleem M.} and Sepanlou, {Sadaf G.} and Shaikh, {Masood Ali} and Ivy Shiue and Sibai, {Abla Mehio} and Silva, {Diego Augusto Santos} and Singh, {Jasvinder A.} and Skogen, {Jens Christoffer} and Terkawi, {Abdullah Sulieman} and Ukwaja, {Kingsley N.} and Ronny Westerman and Naohiro Yonemoto and Seok-Jun Yoon and Younis, {Mustafa Z.} and Zoubida Zaidi and Zaki, {Maysaa El Sayed} and Lim, {Stephen S.} and Haidong Wang and Theo Vos and Mohsen Naghavi and Lopez, {Alan D.} and Murray, {Christopher J.L.} and Mokdad, {Ali H.}",
year = "2017",
month = "8",
day = "1",
doi = "10.1136/annrheumdis-2016-210146",
language = "English",
volume = "76",
pages = "1365--1373",
journal = "Annals of the Rheumatic Diseases",
issn = "0003-4967",
publisher = "BMJ Publishing Group",
number = "8",

}

TY - JOUR

T1 - Burden of musculoskeletal disorders in the Eastern Mediterranean Region, 1990-2013

T2 - Findings from the Global Burden of Disease Study 2013

AU - Moradi-Lakeh, Maziar

AU - Forouzanfar, Mohammad H.

AU - Vollset, Stein Emil

AU - El Bcheraoui, Charbel

AU - Daoud, Farah

AU - Afshin, Ashkan

AU - Charara, Raghid

AU - Khalil, Ibrahim

AU - Higashi, Hideki

AU - Abd El Razek, Mohamed Magdy

AU - Kiadaliri, Aliasghar Ahmad

AU - Alam, Khurshid

AU - Akseer, Nadia

AU - Al-Hamad, Nawal

AU - Ali, Raghib

AU - Almazroa, Mohammad Abdulaziz

AU - Alomari, Mahmoud A.

AU - Al-Rabeeah, Abdullah A.

AU - Alsharif, Ubai

AU - Altirkawi, Khalid A.

AU - Atique, Suleman

AU - Badawi, Alaa

AU - Barrero, Lope H.

AU - Basulaiman, Mohammed

AU - Bazargan-Hejazi, Shahrzad

AU - Bedi, Neeraj

AU - Bensenor, Isabela M.

AU - Buchbinder, Rachelle

AU - Danawi, Hadi

AU - Dharmaratne, Samath D.

AU - Zannad, Faiez

AU - Farvid, Maryam S.

AU - Fereshtehnejad, Seyed Mohammad

AU - Farzadfar, Farshad

AU - Fischer, Florian

AU - Gupta, Rahul

AU - Hamadeh, Randah Ribhi

AU - Hamidi, Samer

AU - Horino, Masako

AU - Hoy, Damian G.

AU - Hsairi, Mohamed

AU - Husseini, Abdullatif

AU - Javanbakht, Mehdi

AU - Jonas, Jost B.

AU - Kasaeian, Amir

AU - Khan, Ejaz Ahmad

AU - Khubchandani, Jagdish

AU - Knudsen, Ann Kristin

AU - Kopec, Jacek A.

AU - Lunevicius, Raimundas

AU - Abd El Razek, Hassan Magdy

AU - Majeed, Azeem

AU - Malekzadeh, Reza

AU - Mate, Kedar

AU - Mehari, Alem

AU - Meltzer, Michele

AU - Memish, Ziad A.

AU - Mirarefin, Mojde

AU - Mohammed, Shafiu

AU - Naheed, Aliya

AU - Obermeyer, Carla Makhlouf

AU - Oh, In Hwan

AU - Park, Eun Kee

AU - Peprah, Emmanuel Kwame

AU - Pourmalek, Farshad

AU - Qorbani, Mostafa

AU - Rafay, Anwar

AU - Rahimi-Movaghar, Vafa

AU - Shiri, Rahman

AU - Rahman, Sajjad Ur

AU - Rai, Rajesh Kumar

AU - Rana, Saleem M.

AU - Sepanlou, Sadaf G.

AU - Shaikh, Masood Ali

AU - Shiue, Ivy

AU - Sibai, Abla Mehio

AU - Silva, Diego Augusto Santos

AU - Singh, Jasvinder A.

AU - Skogen, Jens Christoffer

AU - Terkawi, Abdullah Sulieman

AU - Ukwaja, Kingsley N.

AU - Westerman, Ronny

AU - Yonemoto, Naohiro

AU - Yoon, Seok-Jun

AU - Younis, Mustafa Z.

AU - Zaidi, Zoubida

AU - Zaki, Maysaa El Sayed

AU - Lim, Stephen S.

AU - Wang, Haidong

AU - Vos, Theo

AU - Naghavi, Mohsen

AU - Lopez, Alan D.

AU - Murray, Christopher J.L.

AU - Mokdad, Ali H.

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Objectives We used findings from the Global Burden of Disease Study 2013 to report the burden of musculoskeletal disorders in the Eastern Mediterranean Region (EMR). Methods The burden of musculoskeletal disorders was calculated for the EMR's 22 countries between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, death, years of live lost, years lived with disability and disability-adjusted life years (DALYs). Results For musculoskeletal disorders, the crude DALYs rate per 100 000 increased from 1297.1 (95% uncertainty interval (UI) 924.3-1703.4) in 1990 to 1606.0 (95% UI 1141.2-2130.4) in 2013. During 1990-2013, the total DALYs of musculoskeletal disorders increased by 105.2% in the EMR compared with a 58.0% increase in the rest of the world. The burden of musculoskeletal disorders as a proportion of total DALYs increased from 2.4% (95% UI 1.7-3.0) in 1990 to 4.7% (95% UI 3.6-5.8) in 2013. The range of point prevalence (per 1000) among the EMR countries was 28.2-136.0 for low back pain, 27.3-49.7 for neck pain, 9.7-37.3 for osteoarthritis (OA), 0.6-2.2 for rheumatoid arthritis and 0.1-0.8 for gout. Low back pain and neck pain had the highest burden in EMR countries. Conclusions This study shows a high burden of musculoskeletal disorders, with a faster increase in EMR compared with the rest of the world. The reasons for this faster increase need to be explored. Our findings call for incorporating prevention and control programmes that should include improving health data, addressing risk factors, providing evidence-based care and community programmes to increase awareness.

AB - Objectives We used findings from the Global Burden of Disease Study 2013 to report the burden of musculoskeletal disorders in the Eastern Mediterranean Region (EMR). Methods The burden of musculoskeletal disorders was calculated for the EMR's 22 countries between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, death, years of live lost, years lived with disability and disability-adjusted life years (DALYs). Results For musculoskeletal disorders, the crude DALYs rate per 100 000 increased from 1297.1 (95% uncertainty interval (UI) 924.3-1703.4) in 1990 to 1606.0 (95% UI 1141.2-2130.4) in 2013. During 1990-2013, the total DALYs of musculoskeletal disorders increased by 105.2% in the EMR compared with a 58.0% increase in the rest of the world. The burden of musculoskeletal disorders as a proportion of total DALYs increased from 2.4% (95% UI 1.7-3.0) in 1990 to 4.7% (95% UI 3.6-5.8) in 2013. The range of point prevalence (per 1000) among the EMR countries was 28.2-136.0 for low back pain, 27.3-49.7 for neck pain, 9.7-37.3 for osteoarthritis (OA), 0.6-2.2 for rheumatoid arthritis and 0.1-0.8 for gout. Low back pain and neck pain had the highest burden in EMR countries. Conclusions This study shows a high burden of musculoskeletal disorders, with a faster increase in EMR compared with the rest of the world. The reasons for this faster increase need to be explored. Our findings call for incorporating prevention and control programmes that should include improving health data, addressing risk factors, providing evidence-based care and community programmes to increase awareness.

KW - Epidemiology

KW - Gout

KW - Low Back Pain

KW - Osteoarthritis

KW - Rheumatoid Arthritis

UR - http://www.scopus.com/inward/record.url?scp=85019670184&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85019670184&partnerID=8YFLogxK

U2 - 10.1136/annrheumdis-2016-210146

DO - 10.1136/annrheumdis-2016-210146

M3 - Article

VL - 76

SP - 1365

EP - 1373

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

SN - 0003-4967

IS - 8

ER -