Cancer of the stomach: A review of two hospitals in Korea and Japan

Young Jae Mok, Bum Whan Koo, Chung Woong Whang, Sae Min Kim, Keiichi Maruyama, Mitsuru Sasako, Taira Kinoshita

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

The records of 525 patients with primary adenocarcinoma of the stomach treated at Korea University Hospital (K.U.H.), Seoul, Korea, and 1,932 patients treated at National Cancer Center Hospital (N.C.C.), Tokyo, Japan, over a 7-year period were reviewed to study biologic characteristics and treatment results in the two hospitals. More than 70% of the patients were 41 to 70 years old in both hospitals, though K.U.H. had more younger patients and N.C.C. had more older patients. Comparison in regard to clinicopathologic features showed significant differences in type of cancer, tumor size, depth of invasion, lymph node metastasis, stage, and histologic type. Such a difference mostly was due to a greater frequency of early gastric cancer in N.C.C. patients (51.2%) than in K.U.H. patients (19.0%). Patients of K.U.H. were more likely to have advanced cancer, large invasive tumors, a higher percentage of lymph node metastasis, a higher stage, and more undifferentiated tumors. The 5-year survival rate of all resected cases was 69.5% in N.C.C. and 54.2% in K.U.H. (p>0.05). Those factors which showed a significant difference in clinicopathologic features did not affect the survival difference between the two hospitals except in stage IIIb and signet-ring-cell cancer. The 5-year survival rate for stage IIIb was 18.0% in K.U.H. and 36.8% in N.C.C. It would seem that survival difference in stage IIIb related to extensive lymph node dissection in N.C.C. Survival difference in signetring-cell gastric cancer (31.2% in K.U.H. and 91.0% in N.C.C.) was related to the fact that 79.1% of signet-ring-cell gastric cancer patients in N.C.C. had early gastric cancer. This present study once again demonstrates the importance of early detection in the treatment of gastric cancer and suggests that gastric cancer of two countries is not different.

Original languageEnglish
Pages (from-to)777-782
Number of pages6
JournalWorld Journal of Surgery
Volume17
Issue number6
DOIs
Publication statusPublished - 1993 Nov 1

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Cancer Care Facilities
Korea
Stomach Neoplasms
Japan
Neoplasms
Survival
Survival Rate
Lymph Nodes
Neoplasm Metastasis
Tokyo
Lymph Node Excision
Stomach
Adenocarcinoma
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Mok, Y. J., Koo, B. W., Whang, C. W., Kim, S. M., Maruyama, K., Sasako, M., & Kinoshita, T. (1993). Cancer of the stomach: A review of two hospitals in Korea and Japan. World Journal of Surgery, 17(6), 777-782. https://doi.org/10.1007/BF01659094

Cancer of the stomach : A review of two hospitals in Korea and Japan. / Mok, Young Jae; Koo, Bum Whan; Whang, Chung Woong; Kim, Sae Min; Maruyama, Keiichi; Sasako, Mitsuru; Kinoshita, Taira.

In: World Journal of Surgery, Vol. 17, No. 6, 01.11.1993, p. 777-782.

Research output: Contribution to journalReview article

Mok, YJ, Koo, BW, Whang, CW, Kim, SM, Maruyama, K, Sasako, M & Kinoshita, T 1993, 'Cancer of the stomach: A review of two hospitals in Korea and Japan', World Journal of Surgery, vol. 17, no. 6, pp. 777-782. https://doi.org/10.1007/BF01659094
Mok, Young Jae ; Koo, Bum Whan ; Whang, Chung Woong ; Kim, Sae Min ; Maruyama, Keiichi ; Sasako, Mitsuru ; Kinoshita, Taira. / Cancer of the stomach : A review of two hospitals in Korea and Japan. In: World Journal of Surgery. 1993 ; Vol. 17, No. 6. pp. 777-782.
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abstract = "The records of 525 patients with primary adenocarcinoma of the stomach treated at Korea University Hospital (K.U.H.), Seoul, Korea, and 1,932 patients treated at National Cancer Center Hospital (N.C.C.), Tokyo, Japan, over a 7-year period were reviewed to study biologic characteristics and treatment results in the two hospitals. More than 70{\%} of the patients were 41 to 70 years old in both hospitals, though K.U.H. had more younger patients and N.C.C. had more older patients. Comparison in regard to clinicopathologic features showed significant differences in type of cancer, tumor size, depth of invasion, lymph node metastasis, stage, and histologic type. Such a difference mostly was due to a greater frequency of early gastric cancer in N.C.C. patients (51.2{\%}) than in K.U.H. patients (19.0{\%}). Patients of K.U.H. were more likely to have advanced cancer, large invasive tumors, a higher percentage of lymph node metastasis, a higher stage, and more undifferentiated tumors. The 5-year survival rate of all resected cases was 69.5{\%} in N.C.C. and 54.2{\%} in K.U.H. (p>0.05). Those factors which showed a significant difference in clinicopathologic features did not affect the survival difference between the two hospitals except in stage IIIb and signet-ring-cell cancer. The 5-year survival rate for stage IIIb was 18.0{\%} in K.U.H. and 36.8{\%} in N.C.C. It would seem that survival difference in stage IIIb related to extensive lymph node dissection in N.C.C. Survival difference in signetring-cell gastric cancer (31.2{\%} in K.U.H. and 91.0{\%} in N.C.C.) was related to the fact that 79.1{\%} of signet-ring-cell gastric cancer patients in N.C.C. had early gastric cancer. This present study once again demonstrates the importance of early detection in the treatment of gastric cancer and suggests that gastric cancer of two countries is not different.",
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