Candida spondylodiscitis with epidural abscess treated with voriconazole

Yun Noh Ji, Yeon Heo Jung, Suk Choi Won, Mi Jo Yu, Young Song Joon, Jin Cheong Hee, Joo Kim Woo

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    Candida spondylodiscitis with epidural abscess is rarely reported and known to be the late complication of candidemia. A 48-years-old man presented with 4 weeks of progressively aggravating low back pain. He had a history of fungemia caused by Candida albicans 4 months earlier, for which he had been treated successfully with systemic fluconazole. The MRI of lumbar spine demonstrated the spondylodiscitis with multiple epidural abscesses at the L2/3 level. Along with the surgical interventions including abscess drainage, the intravenous amphotericin B administration was begun. Culture of drained pus yielded the growth of Candida albicans. After therapy with parenteral amphotericin B for 2 weeks followed by oral fluconazole for 8 weeks, the back pain resolved. However the low back pain and inflammation relapsed during oral fluconazole therapy. Thereafter oral voriconazole had been administered for 24 weeks and the patient showed complete recovery and no recurrence.

    Original languageEnglish
    Pages (from-to)145-149
    Number of pages5
    JournalKorean Journal of Medical Mycology
    Volume14
    Issue number3
    Publication statusPublished - 2009 Sep

    Keywords

    • Candida
    • Spondylodiscitis
    • Voriconazole

    ASJC Scopus subject areas

    • Infectious Diseases

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