Candida spondylodiscitis with epidural abscess treated with voriconazole

Yun Noh Ji, Yeon Heo Jung, Suk Choi Won, Mi Jo Yu, Young Song Joon, Jin Cheong Hee, Joo Kim Woo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Candida spondylodiscitis with epidural abscess is rarely reported and known to be the late complication of candidemia. A 48-years-old man presented with 4 weeks of progressively aggravating low back pain. He had a history of fungemia caused by Candida albicans 4 months earlier, for which he had been treated successfully with systemic fluconazole. The MRI of lumbar spine demonstrated the spondylodiscitis with multiple epidural abscesses at the L2/3 level. Along with the surgical interventions including abscess drainage, the intravenous amphotericin B administration was begun. Culture of drained pus yielded the growth of Candida albicans. After therapy with parenteral amphotericin B for 2 weeks followed by oral fluconazole for 8 weeks, the back pain resolved. However the low back pain and inflammation relapsed during oral fluconazole therapy. Thereafter oral voriconazole had been administered for 24 weeks and the patient showed complete recovery and no recurrence.

Original languageEnglish
Pages (from-to)145-149
Number of pages5
JournalKorean Journal of Medical Mycology
Volume14
Issue number3
Publication statusPublished - 2009 Sep

Keywords

  • Candida
  • Spondylodiscitis
  • Voriconazole

ASJC Scopus subject areas

  • Infectious Diseases

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    Ji, Y. N., Jung, Y. H., Won, S. C., Yu, M. J., Joon, Y. S., Hee, J. C., & Woo, J. K. (2009). Candida spondylodiscitis with epidural abscess treated with voriconazole. Korean Journal of Medical Mycology, 14(3), 145-149.