Capsule endoscopy in small bowel tumors

A multicenter Korean study

Dae Young Cheung, In Seok Lee, Dong Kyung Chang, Jin Oh Kim, Jae Hee Cheon, Byung Ik Jang, Yong Sik Kim, Cheol Hee Park, Kwang Jae Lee, Ki Nam Shim, Ji Kon Ryu, Jae Hyuk Do, Jeong Seop Moon, Byong Duk Ye, Kyung Jo Kim, Yun Jeong Lim, Myung Gyu Choi, Hoon-Jai Chun

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Background and Aim: Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions in a variety of clinical conditions, but studies concerning the practical impact of CE on small bowel tumors are still scarce, especially in the Asian population. The aim of this study was to evaluate the diagnostic and therapeutic impact of CE in the field of small bowel tumors. Methods: CE records consecutively pooled from the beginning of use of CE in Korea, October 2001 until April 2008, in 14 centers throughout Korea were reviewed. Clinical information and CE video images of small bowel tumors were analyzed. Results: A total of 1332 cases undergoing CE were reviewed with all clinical indications. Small bowel tumors were diagnosed with CE in 57 (4.3%) of 1332 patients. The tumors were malignant in 33 cases, and included three adenocarcinomas, eight lymphomas, 20 gastrointestinal stromal tumors, and two metastatic cancers. The most frequent indications for CE in malignant tumors were obscure gastrointestinal bleeding, followed by abdominal pain and weight loss. Thirty of 57 tumors were identified exclusively by CE (diagnostic impact = 30/57), and they were smaller in size (mean, range: 14.3 mm, 2-35 mm) compared to the other tumors detected in radiological studies (48.7 mm, 10-110 mm). Seven patients underwent surgical resection (therapeutic impact = 7/57). Conclusion: CE effectively identifies small bowel tumors that are undetectable by conventional radiological studies (diagnostic impact = 52.6%) and can critically change the therapeutic course (therapeutic impact = 12.3%).

Original languageEnglish
Pages (from-to)1079-1086
Number of pages8
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume25
Issue number6
DOIs
Publication statusPublished - 2010 Jan 1

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Capsule Endoscopy
Multicenter Studies
Neoplasms
Korea
Gastrointestinal Stromal Tumors
Therapeutics
Abdominal Pain
Weight Loss
Lymphoma
Adenocarcinoma

Keywords

  • Capsule endoscopy
  • Small intestine
  • Tumor

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Capsule endoscopy in small bowel tumors : A multicenter Korean study. / Cheung, Dae Young; Lee, In Seok; Chang, Dong Kyung; Kim, Jin Oh; Cheon, Jae Hee; Jang, Byung Ik; Kim, Yong Sik; Park, Cheol Hee; Lee, Kwang Jae; Shim, Ki Nam; Ryu, Ji Kon; Do, Jae Hyuk; Moon, Jeong Seop; Ye, Byong Duk; Kim, Kyung Jo; Lim, Yun Jeong; Choi, Myung Gyu; Chun, Hoon-Jai.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 25, No. 6, 01.01.2010, p. 1079-1086.

Research output: Contribution to journalArticle

Cheung, DY, Lee, IS, Chang, DK, Kim, JO, Cheon, JH, Jang, BI, Kim, YS, Park, CH, Lee, KJ, Shim, KN, Ryu, JK, Do, JH, Moon, JS, Ye, BD, Kim, KJ, Lim, YJ, Choi, MG & Chun, H-J 2010, 'Capsule endoscopy in small bowel tumors: A multicenter Korean study', Journal of Gastroenterology and Hepatology (Australia), vol. 25, no. 6, pp. 1079-1086. https://doi.org/10.1111/j.1440-1746.2010.06292.x
Cheung, Dae Young ; Lee, In Seok ; Chang, Dong Kyung ; Kim, Jin Oh ; Cheon, Jae Hee ; Jang, Byung Ik ; Kim, Yong Sik ; Park, Cheol Hee ; Lee, Kwang Jae ; Shim, Ki Nam ; Ryu, Ji Kon ; Do, Jae Hyuk ; Moon, Jeong Seop ; Ye, Byong Duk ; Kim, Kyung Jo ; Lim, Yun Jeong ; Choi, Myung Gyu ; Chun, Hoon-Jai. / Capsule endoscopy in small bowel tumors : A multicenter Korean study. In: Journal of Gastroenterology and Hepatology (Australia). 2010 ; Vol. 25, No. 6. pp. 1079-1086.
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abstract = "Background and Aim: Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions in a variety of clinical conditions, but studies concerning the practical impact of CE on small bowel tumors are still scarce, especially in the Asian population. The aim of this study was to evaluate the diagnostic and therapeutic impact of CE in the field of small bowel tumors. Methods: CE records consecutively pooled from the beginning of use of CE in Korea, October 2001 until April 2008, in 14 centers throughout Korea were reviewed. Clinical information and CE video images of small bowel tumors were analyzed. Results: A total of 1332 cases undergoing CE were reviewed with all clinical indications. Small bowel tumors were diagnosed with CE in 57 (4.3{\%}) of 1332 patients. The tumors were malignant in 33 cases, and included three adenocarcinomas, eight lymphomas, 20 gastrointestinal stromal tumors, and two metastatic cancers. The most frequent indications for CE in malignant tumors were obscure gastrointestinal bleeding, followed by abdominal pain and weight loss. Thirty of 57 tumors were identified exclusively by CE (diagnostic impact = 30/57), and they were smaller in size (mean, range: 14.3 mm, 2-35 mm) compared to the other tumors detected in radiological studies (48.7 mm, 10-110 mm). Seven patients underwent surgical resection (therapeutic impact = 7/57). Conclusion: CE effectively identifies small bowel tumors that are undetectable by conventional radiological studies (diagnostic impact = 52.6{\%}) and can critically change the therapeutic course (therapeutic impact = 12.3{\%}).",
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T2 - A multicenter Korean study

AU - Cheung, Dae Young

AU - Lee, In Seok

AU - Chang, Dong Kyung

AU - Kim, Jin Oh

AU - Cheon, Jae Hee

AU - Jang, Byung Ik

AU - Kim, Yong Sik

AU - Park, Cheol Hee

AU - Lee, Kwang Jae

AU - Shim, Ki Nam

AU - Ryu, Ji Kon

AU - Do, Jae Hyuk

AU - Moon, Jeong Seop

AU - Ye, Byong Duk

AU - Kim, Kyung Jo

AU - Lim, Yun Jeong

AU - Choi, Myung Gyu

AU - Chun, Hoon-Jai

PY - 2010/1/1

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N2 - Background and Aim: Capsule endoscopy (CE) has proven to be highly effective at detecting small bowel lesions in a variety of clinical conditions, but studies concerning the practical impact of CE on small bowel tumors are still scarce, especially in the Asian population. The aim of this study was to evaluate the diagnostic and therapeutic impact of CE in the field of small bowel tumors. Methods: CE records consecutively pooled from the beginning of use of CE in Korea, October 2001 until April 2008, in 14 centers throughout Korea were reviewed. Clinical information and CE video images of small bowel tumors were analyzed. Results: A total of 1332 cases undergoing CE were reviewed with all clinical indications. Small bowel tumors were diagnosed with CE in 57 (4.3%) of 1332 patients. The tumors were malignant in 33 cases, and included three adenocarcinomas, eight lymphomas, 20 gastrointestinal stromal tumors, and two metastatic cancers. The most frequent indications for CE in malignant tumors were obscure gastrointestinal bleeding, followed by abdominal pain and weight loss. Thirty of 57 tumors were identified exclusively by CE (diagnostic impact = 30/57), and they were smaller in size (mean, range: 14.3 mm, 2-35 mm) compared to the other tumors detected in radiological studies (48.7 mm, 10-110 mm). Seven patients underwent surgical resection (therapeutic impact = 7/57). Conclusion: CE effectively identifies small bowel tumors that are undetectable by conventional radiological studies (diagnostic impact = 52.6%) and can critically change the therapeutic course (therapeutic impact = 12.3%).

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KW - Tumor

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