Abstract
Cardiovascular responses after placebo-cocaine injections were in the same direction as the effect of cocaine iv in 22 male volunteers. Subjects received iv placebo in a room where they had been given repeated doses of iv cocaine. The placebo response consisted of an increase from baseline values of systolic and diastolic blood pressure and pulse rate. The control group, 8 subjects, which was not exposed to a conditioning phase, showed a smaller increase in the pulse rate and systolic blood pressure after the placebo injection. The results, in accordance with animal literature, suggest the existence of cocaine-conditioned effects in humans.
| Original language | English |
|---|---|
| Pages (from-to) | 285-295 |
| Number of pages | 11 |
| Journal | Biological Psychiatry |
| Volume | 25 |
| Issue number | 3 |
| Publication status | Published - 1989 Feb 1 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biological Psychiatry
Cite this
Cardiovascular responses to cocaine placebo in humans : A preliminary report. / Cascella, Nicola; Muntaner, Carles; Kumor, Karen M.; Nagoshi, Craig T.; Jaffe, Jerome H.; Sherer, Michael A.
In: Biological Psychiatry, Vol. 25, No. 3, 01.02.1989, p. 285-295.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cardiovascular responses to cocaine placebo in humans
T2 - A preliminary report
AU - Cascella, Nicola
AU - Muntaner, Carles
AU - Kumor, Karen M.
AU - Nagoshi, Craig T.
AU - Jaffe, Jerome H.
AU - Sherer, Michael A.
PY - 1989/2/1
Y1 - 1989/2/1
N2 - Cardiovascular responses after placebo-cocaine injections were in the same direction as the effect of cocaine iv in 22 male volunteers. Subjects received iv placebo in a room where they had been given repeated doses of iv cocaine. The placebo response consisted of an increase from baseline values of systolic and diastolic blood pressure and pulse rate. The control group, 8 subjects, which was not exposed to a conditioning phase, showed a smaller increase in the pulse rate and systolic blood pressure after the placebo injection. The results, in accordance with animal literature, suggest the existence of cocaine-conditioned effects in humans.
AB - Cardiovascular responses after placebo-cocaine injections were in the same direction as the effect of cocaine iv in 22 male volunteers. Subjects received iv placebo in a room where they had been given repeated doses of iv cocaine. The placebo response consisted of an increase from baseline values of systolic and diastolic blood pressure and pulse rate. The control group, 8 subjects, which was not exposed to a conditioning phase, showed a smaller increase in the pulse rate and systolic blood pressure after the placebo injection. The results, in accordance with animal literature, suggest the existence of cocaine-conditioned effects in humans.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024511109&partnerID=8YFLogxK
M3 - Article
VL - 25
SP - 285
EP - 295
JO - Biological Psychiatry
JF - Biological Psychiatry
SN - 0006-3223
IS - 3
ER -