Case of pancreatic cancer as a recurrence of intraductal papillary mucinous neoplasm following surgical resection

Sae-Byeol Choi, Hye Sung Jo, Sang Yong Choi

Research output: Contribution to journalLetter

Abstract

Pancreatic cancer is a devastating malady with proclivity for early metastasis, accounting for its poor prognosis. Pancreatic ductal adenocarcinoma, the most common type of pancreatic malignancy, exhibits an over-expression of several growth factors such as epidermal growth factor and transforming growth factor beta, which correlate with a decrease in patient survival. These growth factors as well as hypoxia-reoxygenation conditions have been shown to increase pancreatic tumor cell invasiveness. This review will focus on the signaling pathways used by these distinct microenvironmental factors to promote extracellular matrix degradation and invasion by pancreatic tumor cells.

Original languageEnglish
Pages (from-to)411-412
Number of pages2
JournalJournal of the Pancreas
Volume15
Issue number4
DOIs
Publication statusPublished - 2014 Jan 1

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Keywords

  • Adenocarcinoma
  • And serous
  • Cystic
  • Local
  • Mucinous
  • Neoplasm recurrence
  • Neoplasms
  • Pancreatectomy
  • Pancreatic neoplasms
  • Papillary

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology

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