Case report of pulmonary sarcoidosis suspected to be pulmonary metastasis in a patient with breast cancer

Hye Sook Kim, Suk young Lee, Sang Cheul Oh, Chul Won Choi, Jun Suk Kim, Jae Hong Seo

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Standard endocrine therapy and chemotherapy can induce long-term remission in breast cancer patients; however, breast cancer can recur at any site. Pulmonary nodules with lymphadenopathy in advanced cancer patients are likely to be assumed as metastases. A 44-year-old woman with a history of breast cancer was presented to our institution with abnormal findings on 18-fluorodeoxyglucose positron emission tomography imaging, which suggested lung metastasis. She had previously been diagnosed with breast cancer (T1N2M0, Stage IIIa, intraductal carcinoma, triple negative cancer). Histological analysis of the mediastinal lymph node biopsy demonstrated sarcoidosis, showing a chronic, non-caseating, granulomatous inflammation. Our case highlights the need for non-malignant diagnoses in those with prior malignancies, and the need for histological evaluations in the event of first recurrence following potentially curative therapy.

Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalCancer Research and Treatment
Volume46
Issue number3
DOIs
Publication statusPublished - 2014 Jan 1

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Pulmonary Sarcoidosis
Breast Neoplasms
Neoplasm Metastasis
Lung
Neoplasms
Carcinoma, Intraductal, Noninfiltrating
Sarcoidosis
Positron-Emission Tomography
Lymph Nodes
Inflammation
Biopsy
Recurrence
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Case report of pulmonary sarcoidosis suspected to be pulmonary metastasis in a patient with breast cancer. / Kim, Hye Sook; Lee, Suk young; Oh, Sang Cheul; Choi, Chul Won; Kim, Jun Suk; Seo, Jae Hong.

In: Cancer Research and Treatment, Vol. 46, No. 3, 01.01.2014, p. 317-321.

Research output: Contribution to journalArticle

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AB - Standard endocrine therapy and chemotherapy can induce long-term remission in breast cancer patients; however, breast cancer can recur at any site. Pulmonary nodules with lymphadenopathy in advanced cancer patients are likely to be assumed as metastases. A 44-year-old woman with a history of breast cancer was presented to our institution with abnormal findings on 18-fluorodeoxyglucose positron emission tomography imaging, which suggested lung metastasis. She had previously been diagnosed with breast cancer (T1N2M0, Stage IIIa, intraductal carcinoma, triple negative cancer). Histological analysis of the mediastinal lymph node biopsy demonstrated sarcoidosis, showing a chronic, non-caseating, granulomatous inflammation. Our case highlights the need for non-malignant diagnoses in those with prior malignancies, and the need for histological evaluations in the event of first recurrence following potentially curative therapy.

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