Catheter ablation of atrial fibrillation in patients with chronic lung disease

Seung Young Roh, Jongil Choi, Juneyoung Lee, Jae Jin Kwak, Jae Seok Park, Ji Bak Kim, Hong Euy Lim, Young Hoon Kim

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Background-Chronic lung disease (CLD) is one of the important underlying diseases of atrial fibrillation (AF). The outcomes after radiofrequency catheter ablation of AF in patients with CLD have not yet been reported. We investigated the electroanatomic alterations in pulmonary veins (PVs) in CLD patients with AF and assessed their effect on the outcomes of radiofrequency catheter ablation of AF. Method and Results-We assessed 15 patients who had CLD and underwent radiofrequency catheter ablation of AF. CLD included chronic obstructive pulmonary disease, a tuberculosis-destroyed lung, and interstitial lung disease. For controls, we selected 60 sex-, age-, and procedure era-matched non-CLD patients who received radiofrequency catheter ablation for AF (4 controls for each CLD patient). Eight patients had chronic obstructive pulmonary disease, 6 had a tuberculosis-destroyed lung, and 1 had interstitial lung disease. PV morphology in the affected lung was altered significantly, ie, obliteration, pulling of the PVs toward the destroyed lung, or compensatory bulging of the PV antrum. These alterations were related to arrhythmogenicity in 6 (40%) of 15 patients with CLD. Non-PV foci were more common in the CLD group (4/15, 26.7%) than in the control group (3/60, 5.0%; P=0.025). All non-PV foci were located in the right atrium. The AF recurrence rate in the CLD group (26.7%, 4/15) was similar to that in the control group (18.3%, 11/60; P=0.45). Conclusions-Significant alteration of PV anatomy was related to arrhythmogenicity, and non-PV foci from the right atrium were commonly observed in the CLD group. Radiofrequency catheter ablation can be performed safely for AF in CLD patients with a comparable success rate to that in patients with normal lungs.

Original languageEnglish
Pages (from-to)815-822
Number of pages8
JournalCirculation: Arrhythmia and Electrophysiology
Volume4
Issue number6
DOIs
Publication statusPublished - 2011 Dec 1

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Catheter Ablation
Atrial Fibrillation
Lung Diseases
Chronic Disease
Pulmonary Veins
Lung
Veins
Interstitial Lung Diseases
Heart Atria
Chronic Obstructive Pulmonary Disease
Tuberculosis
Control Groups
Anatomy

Keywords

  • Ablation
  • Atrial fibrillation
  • Catheter ablation
  • Lung
  • Pulmonary heart disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Catheter ablation of atrial fibrillation in patients with chronic lung disease. / Roh, Seung Young; Choi, Jongil; Lee, Juneyoung; Kwak, Jae Jin; Park, Jae Seok; Kim, Ji Bak; Lim, Hong Euy; Kim, Young Hoon.

In: Circulation: Arrhythmia and Electrophysiology, Vol. 4, No. 6, 01.12.2011, p. 815-822.

Research output: Contribution to journalArticle

Roh, Seung Young ; Choi, Jongil ; Lee, Juneyoung ; Kwak, Jae Jin ; Park, Jae Seok ; Kim, Ji Bak ; Lim, Hong Euy ; Kim, Young Hoon. / Catheter ablation of atrial fibrillation in patients with chronic lung disease. In: Circulation: Arrhythmia and Electrophysiology. 2011 ; Vol. 4, No. 6. pp. 815-822.
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AU - Kim, Ji Bak

AU - Lim, Hong Euy

AU - Kim, Young Hoon

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AB - Background-Chronic lung disease (CLD) is one of the important underlying diseases of atrial fibrillation (AF). The outcomes after radiofrequency catheter ablation of AF in patients with CLD have not yet been reported. We investigated the electroanatomic alterations in pulmonary veins (PVs) in CLD patients with AF and assessed their effect on the outcomes of radiofrequency catheter ablation of AF. Method and Results-We assessed 15 patients who had CLD and underwent radiofrequency catheter ablation of AF. CLD included chronic obstructive pulmonary disease, a tuberculosis-destroyed lung, and interstitial lung disease. For controls, we selected 60 sex-, age-, and procedure era-matched non-CLD patients who received radiofrequency catheter ablation for AF (4 controls for each CLD patient). Eight patients had chronic obstructive pulmonary disease, 6 had a tuberculosis-destroyed lung, and 1 had interstitial lung disease. PV morphology in the affected lung was altered significantly, ie, obliteration, pulling of the PVs toward the destroyed lung, or compensatory bulging of the PV antrum. These alterations were related to arrhythmogenicity in 6 (40%) of 15 patients with CLD. Non-PV foci were more common in the CLD group (4/15, 26.7%) than in the control group (3/60, 5.0%; P=0.025). All non-PV foci were located in the right atrium. The AF recurrence rate in the CLD group (26.7%, 4/15) was similar to that in the control group (18.3%, 11/60; P=0.45). Conclusions-Significant alteration of PV anatomy was related to arrhythmogenicity, and non-PV foci from the right atrium were commonly observed in the CLD group. Radiofrequency catheter ablation can be performed safely for AF in CLD patients with a comparable success rate to that in patients with normal lungs.

KW - Ablation

KW - Atrial fibrillation

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KW - Lung

KW - Pulmonary heart disease

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