Abstract
Background: This prospective, randomized, double-blind study aimed to determine whether caudal midazolam combined with ropivacaine affects anesthetic requirements, recovery profiles, and post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty. Methods: Sixty boys (2-5 years old) received caudal injections of 0.2% ropivacaine 1 ml/kg and epinephrine 1 : 200,000 with (RM group) or without (R group) 50 μg/kg of midazolam under sevoflurane anesthesia. The sevoflurane requirement was determined by adjusting to a bispectral index score=50. Results: Concentrations of end-tidal sevoflurane (ETsevo%) after induction were similar in both groups. After caudal block, ETsevo% before and after surgical stimuli did not show significant intra- or intergroup differences. Recovery characteristics, including post-operative sedations, were similar in both groups. Post-operative pain scores were significantly lower in the RM group than the R group. Conclusions: Caudal midazolam (50 μg/kg) added to 2% ropivacaine did not influence sevoflurane requirement or recovery but improved post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.
| Original language | English |
|---|---|
| Pages (from-to) | 1411-1414 |
| Number of pages | 4 |
| Journal | Acta Anaesthesiologica Scandinavica |
| Volume | 52 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2008 Nov 1 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
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Caudal midazolam does not affect sevoflurane requirements and recovery in pediatric day-case hernioplasty. / Hong, J. Y.; Lee, I. H.; Shin, S. K.; Park, E. Y.; Ban, S. Y.; Cho, Jang-Eun; Kil, H. K.
In: Acta Anaesthesiologica Scandinavica, Vol. 52, No. 10, 01.11.2008, p. 1411-1414.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Caudal midazolam does not affect sevoflurane requirements and recovery in pediatric day-case hernioplasty
AU - Hong, J. Y.
AU - Lee, I. H.
AU - Shin, S. K.
AU - Park, E. Y.
AU - Ban, S. Y.
AU - Cho, Jang-Eun
AU - Kil, H. K.
PY - 2008/11/1
Y1 - 2008/11/1
N2 - Background: This prospective, randomized, double-blind study aimed to determine whether caudal midazolam combined with ropivacaine affects anesthetic requirements, recovery profiles, and post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty. Methods: Sixty boys (2-5 years old) received caudal injections of 0.2% ropivacaine 1 ml/kg and epinephrine 1 : 200,000 with (RM group) or without (R group) 50 μg/kg of midazolam under sevoflurane anesthesia. The sevoflurane requirement was determined by adjusting to a bispectral index score=50. Results: Concentrations of end-tidal sevoflurane (ETsevo%) after induction were similar in both groups. After caudal block, ETsevo% before and after surgical stimuli did not show significant intra- or intergroup differences. Recovery characteristics, including post-operative sedations, were similar in both groups. Post-operative pain scores were significantly lower in the RM group than the R group. Conclusions: Caudal midazolam (50 μg/kg) added to 2% ropivacaine did not influence sevoflurane requirement or recovery but improved post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.
AB - Background: This prospective, randomized, double-blind study aimed to determine whether caudal midazolam combined with ropivacaine affects anesthetic requirements, recovery profiles, and post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty. Methods: Sixty boys (2-5 years old) received caudal injections of 0.2% ropivacaine 1 ml/kg and epinephrine 1 : 200,000 with (RM group) or without (R group) 50 μg/kg of midazolam under sevoflurane anesthesia. The sevoflurane requirement was determined by adjusting to a bispectral index score=50. Results: Concentrations of end-tidal sevoflurane (ETsevo%) after induction were similar in both groups. After caudal block, ETsevo% before and after surgical stimuli did not show significant intra- or intergroup differences. Recovery characteristics, including post-operative sedations, were similar in both groups. Post-operative pain scores were significantly lower in the RM group than the R group. Conclusions: Caudal midazolam (50 μg/kg) added to 2% ropivacaine did not influence sevoflurane requirement or recovery but improved post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.
UR - http://www.scopus.com/inward/record.url?scp=54049111386&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=54049111386&partnerID=8YFLogxK
U2 - 10.1111/j.1399-6576.2008.01727.x
DO - 10.1111/j.1399-6576.2008.01727.x
M3 - Article
C2 - 19025535
AN - SCOPUS:54049111386
VL - 52
SP - 1411
EP - 1414
JO - Acta Anaesthesiologica Scandinavica
JF - Acta Anaesthesiologica Scandinavica
SN - 0001-5172
IS - 10
ER -