Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction

Jaehoon Kim, Junghyo Yoon, Hyo Eun Jeong, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Here, we present a simple method to generate type 1 collagen (COL1) microbeads which are uniform and size controllable and to coat cells on them with high cell viability. We show that COL1 microbead is suitable for making micro-scaled tissue unit and confirmed that morphological characteristics of COL1 microbead is dependent on cell types showing various cell-ECM interaction. We expect ECM microbeads can be applicable for not only tissue reconstitution, but also quantitative studies for cell-ECM interactions.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages494-496
Number of pages3
ISBN (Print)9780979806476
Publication statusPublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period14/10/2614/10/30

Keywords

  • Collagen
  • Extracellular matrix
  • Microbead
  • Tissue engineering

ASJC Scopus subject areas

  • Control and Systems Engineering

Fingerprint Dive into the research topics of 'Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction'. Together they form a unique fingerprint.

  • Cite this

    Kim, J., Yoon, J., Jeong, H. E., & Chung, S. (2014). Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 494-496). Chemical and Biological Microsystems Society.