Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction

Jaehoon Kim, Junghyo Yoon, Hyo Eun Jeong, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Here, we present a simple method to generate type 1 collagen (COL1) microbeads which are uniform and size controllable and to coat cells on them with high cell viability. We show that COL1 microbead is suitable for making micro-scaled tissue unit and confirmed that morphological characteristics of COL1 microbead is dependent on cell types showing various cell-ECM interaction. We expect ECM microbeads can be applicable for not only tissue reconstitution, but also quantitative studies for cell-ECM interactions.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages494-496
Number of pages3
ISBN (Print)9780979806476
Publication statusPublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period14/10/2614/10/30

Fingerprint

Tissue
Collagen
Cells

Keywords

  • Collagen
  • Extracellular matrix
  • Microbead
  • Tissue engineering

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Kim, J., Yoon, J., Jeong, H. E., & Chung, S. (2014). Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 494-496). Chemical and Biological Microsystems Society.

Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction. / Kim, Jaehoon; Yoon, Junghyo; Jeong, Hyo Eun; Chung, Seok.

18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. p. 494-496.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kim, J, Yoon, J, Jeong, HE & Chung, S 2014, Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction. in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, pp. 494-496, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, United States, 14/10/26.
Kim J, Yoon J, Jeong HE, Chung S. Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society. 2014. p. 494-496
Kim, Jaehoon ; Yoon, Junghyo ; Jeong, Hyo Eun ; Chung, Seok. / Cell coated extracellular matrix (ECM) microbeads and morphological analysis of cell-ECM interaction. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. pp. 494-496
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