Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues

Shubo Du, Danyang Wang, Jun Seok Lee, Bo Peng, Jingyan Ge, Shao Q. Yao

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

We have developed a versatile antibody-assisted strategy for the imaging and profiling of newly synthesized proteomes in a cell-specific manner. This strategy remained highly selective even in heterogeneous co-cultured cells, thus enabling labeling and enrichment of nascent proteomes from targeted cells without the need for physical separation.

Original languageEnglish
Pages (from-to)8443-8446
Number of pages4
JournalChemical Communications
Volume53
Issue number60
DOIs
Publication statusPublished - 2017
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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