Central corneal thickness and anterior scleral thickness in korean patients with open-angle glaucoma: An anterior segment optical coherence tomography study

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Abstract

Purpose: To assess the correlation between central corneal thickness (CCT) and anterior scleral thickness (AST) in Korean patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Patients and Methods: Consecutive patients with POAG, NTG, and normal individuals were recruited. Anterior segment optical coherence tomography (AS-OCT, Visante) was used to measure CCT and AST. The AST was measured 2 mm posterior to the scleral spur in the temporal meridian. Statistical analysis of the data included ANOVA and Pearson correlation analysis. Results: One hundred and eight participants (36 with NTG, 35 with POAG, and 37 normal individuals) were enrolled. The CCT (NTG 514.81±25.03 μm; POAG 534.43±34.79 μm; controls 536.70±32.11 μm) was found to be thinner in patients with NTG compared with POAG and the control eyes (P=0.023; P=0.009). The AST (NTG 738.53±53.63 μm; POAG 771.86±53.75 μm; controls 783.62±57.03 μm) was thinner in the patients with NTG compared with POAG and the normal controls (P=0.032; P=0.002). No significant difference in AST was found among the POAG and control eyes (P=0.636). A correlation between CCT and AST was found only among the patients with NTG (r=0.469, P=0.004). However, no correlation was observed between CCT and AST in patients with POAG and controls. CONCLUSIONS: Anterior scleral thickness was correlated with CCT in the NTG group, but this correlation was not observed among the POAG or control groups.

Original languageEnglish
Pages (from-to)95-99
Number of pages5
JournalJournal of Glaucoma
Volume20
Issue number2
DOIs
Publication statusPublished - 2011 Feb 1

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Low Tension Glaucoma
Open Angle Glaucoma
Optical Coherence Tomography
Primary Open Angle Glaucoma
Meridians
Statistical Data Interpretation
Analysis of Variance

Keywords

  • Anterior segment optical coherence tomography
  • central corneal thickness
  • glaucoma
  • scleral thickness

ASJC Scopus subject areas

  • Ophthalmology

Cite this

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title = "Central corneal thickness and anterior scleral thickness in korean patients with open-angle glaucoma: An anterior segment optical coherence tomography study",
abstract = "Purpose: To assess the correlation between central corneal thickness (CCT) and anterior scleral thickness (AST) in Korean patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Patients and Methods: Consecutive patients with POAG, NTG, and normal individuals were recruited. Anterior segment optical coherence tomography (AS-OCT, Visante) was used to measure CCT and AST. The AST was measured 2 mm posterior to the scleral spur in the temporal meridian. Statistical analysis of the data included ANOVA and Pearson correlation analysis. Results: One hundred and eight participants (36 with NTG, 35 with POAG, and 37 normal individuals) were enrolled. The CCT (NTG 514.81±25.03 μm; POAG 534.43±34.79 μm; controls 536.70±32.11 μm) was found to be thinner in patients with NTG compared with POAG and the control eyes (P=0.023; P=0.009). The AST (NTG 738.53±53.63 μm; POAG 771.86±53.75 μm; controls 783.62±57.03 μm) was thinner in the patients with NTG compared with POAG and the normal controls (P=0.032; P=0.002). No significant difference in AST was found among the POAG and control eyes (P=0.636). A correlation between CCT and AST was found only among the patients with NTG (r=0.469, P=0.004). However, no correlation was observed between CCT and AST in patients with POAG and controls. CONCLUSIONS: Anterior scleral thickness was correlated with CCT in the NTG group, but this correlation was not observed among the POAG or control groups.",
keywords = "Anterior segment optical coherence tomography, central corneal thickness, glaucoma, scleral thickness",
author = "Chungkwon Yoo and Youngsub Eom and Young-Woo Suh and Kim, {Yong Yeon}",
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T1 - Central corneal thickness and anterior scleral thickness in korean patients with open-angle glaucoma

T2 - An anterior segment optical coherence tomography study

AU - Yoo, Chungkwon

AU - Eom, Youngsub

AU - Suh, Young-Woo

AU - Kim, Yong Yeon

PY - 2011/2/1

Y1 - 2011/2/1

N2 - Purpose: To assess the correlation between central corneal thickness (CCT) and anterior scleral thickness (AST) in Korean patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Patients and Methods: Consecutive patients with POAG, NTG, and normal individuals were recruited. Anterior segment optical coherence tomography (AS-OCT, Visante) was used to measure CCT and AST. The AST was measured 2 mm posterior to the scleral spur in the temporal meridian. Statistical analysis of the data included ANOVA and Pearson correlation analysis. Results: One hundred and eight participants (36 with NTG, 35 with POAG, and 37 normal individuals) were enrolled. The CCT (NTG 514.81±25.03 μm; POAG 534.43±34.79 μm; controls 536.70±32.11 μm) was found to be thinner in patients with NTG compared with POAG and the control eyes (P=0.023; P=0.009). The AST (NTG 738.53±53.63 μm; POAG 771.86±53.75 μm; controls 783.62±57.03 μm) was thinner in the patients with NTG compared with POAG and the normal controls (P=0.032; P=0.002). No significant difference in AST was found among the POAG and control eyes (P=0.636). A correlation between CCT and AST was found only among the patients with NTG (r=0.469, P=0.004). However, no correlation was observed between CCT and AST in patients with POAG and controls. CONCLUSIONS: Anterior scleral thickness was correlated with CCT in the NTG group, but this correlation was not observed among the POAG or control groups.

AB - Purpose: To assess the correlation between central corneal thickness (CCT) and anterior scleral thickness (AST) in Korean patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Patients and Methods: Consecutive patients with POAG, NTG, and normal individuals were recruited. Anterior segment optical coherence tomography (AS-OCT, Visante) was used to measure CCT and AST. The AST was measured 2 mm posterior to the scleral spur in the temporal meridian. Statistical analysis of the data included ANOVA and Pearson correlation analysis. Results: One hundred and eight participants (36 with NTG, 35 with POAG, and 37 normal individuals) were enrolled. The CCT (NTG 514.81±25.03 μm; POAG 534.43±34.79 μm; controls 536.70±32.11 μm) was found to be thinner in patients with NTG compared with POAG and the control eyes (P=0.023; P=0.009). The AST (NTG 738.53±53.63 μm; POAG 771.86±53.75 μm; controls 783.62±57.03 μm) was thinner in the patients with NTG compared with POAG and the normal controls (P=0.032; P=0.002). No significant difference in AST was found among the POAG and control eyes (P=0.636). A correlation between CCT and AST was found only among the patients with NTG (r=0.469, P=0.004). However, no correlation was observed between CCT and AST in patients with POAG and controls. CONCLUSIONS: Anterior scleral thickness was correlated with CCT in the NTG group, but this correlation was not observed among the POAG or control groups.

KW - Anterior segment optical coherence tomography

KW - central corneal thickness

KW - glaucoma

KW - scleral thickness

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