Cerebral syphilitic gumma mimicking a brain tumor in the relapse of secondary syphilis in a human immunodeficiency virus-negative patient

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13 Citations (Scopus)

Abstract

Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalJournal of Korean Neurosurgical Society
Volume53
Issue number3
DOIs
Publication statusPublished - 2013 May 1

Fingerprint

Neurosyphilis
Dysarthria
Ceftriaxone
Syphilis
Exanthema
Viruses
Brain Neoplasms
Cerebrospinal Fluid
Tumors
Brain
Fever
Thorax
Immunoglobulin G
Tomography
X-Rays
HIV
Cerebrospinal fluid
Recurrence
Skin
Antibodies

Keywords

  • Ceftriaxone
  • Gummatous neurosyphilis
  • HIV negative
  • Latent syphilis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Surgery
  • Clinical Neurology

Cite this

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title = "Cerebral syphilitic gumma mimicking a brain tumor in the relapse of secondary syphilis in a human immunodeficiency virus-negative patient",
abstract = "Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.",
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AU - Min, Ja Kim

AU - Chae, Yang Seok

AU - Kang, Shin-Hyuk

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AB - Diagnosis of cerebral syphilitic gumma is frequently determined at the time of surgery, because imaging and laboratory findings demonstrate the elusive results. A 59-year-old woman presenting dysarthria showed a mass on her brain computed tomography. She was first suspected of brain tumor, but histological results from surgical resection revealed cerebral gumma due to neurosyphilis. After operation, she presented fever and rash with an infiltration on a chest X-ray. Histological assessment of skin was consistent with syphilis. Fluorescent treponemal antibody absorbed test IgG in cerebrospinal fluid was positive. She was successfully treated with ceftriaxone for 14 days.

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