Cerebral vasoreactivity by transcranial Doppler in carbon disulfide poisoning cases in Korea

Eun Il Lee, Myung Hyun Kim

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The abnormalities of cerebral vasoreactivity were evaluated in CS2 poisoning cases. In 34 retired workers with CS2 poisoning (case group) and 20 healthy individuals (control group), blood flow velocities were measured in the middle cerebral arteries (MCA) by transcranial Doppler. Compared with the control group, the case group showed lower mean values of blood flow velocities and pulsatile indices. The differences in CO2 reactivities of both groups were remarkable (1.10-2.19% decrease/mmHg CO2 for cases and 3.35-5.08 for controls). Multiple regression analyses were conducted to adjust the effect of age, sex, and exposure level (non-low-high exposure) to CO2 reactivity and pulsatile index. The exposure level was statistically significant in the regression model for CO2 reactivity of both MCA and for pulsatile index of the right MCA. Our study noted a decrease of CO2 reactivity and pulsatile index of cerebral vessels related with CS2 exposure. These findings suggested that CS2 exposure could lead to a decrease of cerebral vasoreactivities by the atherosclerotic change of cerebral vessels.

Original languageEnglish
Pages (from-to)645-651
Number of pages7
JournalJournal of Korean Medical Science
Volume13
Issue number6
Publication statusPublished - 1998 Dec 1

Fingerprint

Carbon Disulfide
Middle Cerebral Artery
Korea
Poisoning
Blood Flow Velocity
Control Groups
Regression Analysis

Keywords

  • Atherosclerosis
  • Carbon disulfide
  • Transcranial sonography, Doppler
  • Ultrasonography

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cerebral vasoreactivity by transcranial Doppler in carbon disulfide poisoning cases in Korea. / Lee, Eun Il; Kim, Myung Hyun.

In: Journal of Korean Medical Science, Vol. 13, No. 6, 01.12.1998, p. 645-651.

Research output: Contribution to journalArticle

@article{da33c4e14c134e34bae24bfff72e1ece,
title = "Cerebral vasoreactivity by transcranial Doppler in carbon disulfide poisoning cases in Korea",
abstract = "The abnormalities of cerebral vasoreactivity were evaluated in CS2 poisoning cases. In 34 retired workers with CS2 poisoning (case group) and 20 healthy individuals (control group), blood flow velocities were measured in the middle cerebral arteries (MCA) by transcranial Doppler. Compared with the control group, the case group showed lower mean values of blood flow velocities and pulsatile indices. The differences in CO2 reactivities of both groups were remarkable (1.10-2.19{\%} decrease/mmHg CO2 for cases and 3.35-5.08 for controls). Multiple regression analyses were conducted to adjust the effect of age, sex, and exposure level (non-low-high exposure) to CO2 reactivity and pulsatile index. The exposure level was statistically significant in the regression model for CO2 reactivity of both MCA and for pulsatile index of the right MCA. Our study noted a decrease of CO2 reactivity and pulsatile index of cerebral vessels related with CS2 exposure. These findings suggested that CS2 exposure could lead to a decrease of cerebral vasoreactivities by the atherosclerotic change of cerebral vessels.",
keywords = "Atherosclerosis, Carbon disulfide, Transcranial sonography, Doppler, Ultrasonography",
author = "Lee, {Eun Il} and Kim, {Myung Hyun}",
year = "1998",
month = "12",
day = "1",
language = "English",
volume = "13",
pages = "645--651",
journal = "Journal of Korean Medical Science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "6",

}

TY - JOUR

T1 - Cerebral vasoreactivity by transcranial Doppler in carbon disulfide poisoning cases in Korea

AU - Lee, Eun Il

AU - Kim, Myung Hyun

PY - 1998/12/1

Y1 - 1998/12/1

N2 - The abnormalities of cerebral vasoreactivity were evaluated in CS2 poisoning cases. In 34 retired workers with CS2 poisoning (case group) and 20 healthy individuals (control group), blood flow velocities were measured in the middle cerebral arteries (MCA) by transcranial Doppler. Compared with the control group, the case group showed lower mean values of blood flow velocities and pulsatile indices. The differences in CO2 reactivities of both groups were remarkable (1.10-2.19% decrease/mmHg CO2 for cases and 3.35-5.08 for controls). Multiple regression analyses were conducted to adjust the effect of age, sex, and exposure level (non-low-high exposure) to CO2 reactivity and pulsatile index. The exposure level was statistically significant in the regression model for CO2 reactivity of both MCA and for pulsatile index of the right MCA. Our study noted a decrease of CO2 reactivity and pulsatile index of cerebral vessels related with CS2 exposure. These findings suggested that CS2 exposure could lead to a decrease of cerebral vasoreactivities by the atherosclerotic change of cerebral vessels.

AB - The abnormalities of cerebral vasoreactivity were evaluated in CS2 poisoning cases. In 34 retired workers with CS2 poisoning (case group) and 20 healthy individuals (control group), blood flow velocities were measured in the middle cerebral arteries (MCA) by transcranial Doppler. Compared with the control group, the case group showed lower mean values of blood flow velocities and pulsatile indices. The differences in CO2 reactivities of both groups were remarkable (1.10-2.19% decrease/mmHg CO2 for cases and 3.35-5.08 for controls). Multiple regression analyses were conducted to adjust the effect of age, sex, and exposure level (non-low-high exposure) to CO2 reactivity and pulsatile index. The exposure level was statistically significant in the regression model for CO2 reactivity of both MCA and for pulsatile index of the right MCA. Our study noted a decrease of CO2 reactivity and pulsatile index of cerebral vessels related with CS2 exposure. These findings suggested that CS2 exposure could lead to a decrease of cerebral vasoreactivities by the atherosclerotic change of cerebral vessels.

KW - Atherosclerosis

KW - Carbon disulfide

KW - Transcranial sonography, Doppler

KW - Ultrasonography

UR - http://www.scopus.com/inward/record.url?scp=0032238274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032238274&partnerID=8YFLogxK

M3 - Article

C2 - 9886174

AN - SCOPUS:0032238274

VL - 13

SP - 645

EP - 651

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

SN - 1011-8934

IS - 6

ER -