Challenges in wide implementation of genome editing for crop improvement

Je Hyeong Jung, Yong Weon Seo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Genome editing technologies using customizable sequence specific nucleases (SSNs) enables precise genome modification in plants, which has revolutionized functional genomics research as well as crop improvement. Applicability of SSN-mediated genome editing ranges from targeted gene knockout and single base modification to multiple gene stacking into desired genomic sites. However, there are still considerable challenges in implementing genome editing technologies for practical crop improvement. Here, we briefly discuss the technological challenges, especially those associated with the delivery of SSNs and with homologous recombination-mediated genome editing, and address some promising solutions to overcome the issues.

Original languageEnglish
Pages (from-to)129-135
Number of pages7
JournalJournal of Crop Science and Biotechnology
Volume20
Issue number2
DOIs
Publication statusPublished - 2017 Jun 1

Keywords

  • crop improvement
  • Genome editing
  • homologous recombination (HR)
  • sequence specific nucleases (SSNs)

ASJC Scopus subject areas

  • Biotechnology
  • Agronomy and Crop Science
  • Plant Science

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