Purpose: To measure the effect of spherical aberration correction by aspheric intraocular lenses (IOLs) based on pupil diameter, and to determine the minimum pupil diameter for each aspheric IOL. Design: Retrospective cross-sectional study. Methods: Eight-six patients (169 eyes) who were implanted with a HOYA AF-1 NY-60 (HOYA Corporation) or Tecnis ZCB00 1-piece IOL (Abbott Medical Optics Inc) were enrolled. Ocular, corneal, and internal spherical aberrations were measured at the 1-month postoperative visit using the Wavefront Analyzer KR-1W (Topcon). Minimum pupil diameter, which is required for each aspheric IOL to be effective, was calculated using a regression equation. Results: The mean value of internal spherical aberration of the Tecnis ZCB00 group (-0.09 ± 0.094 μm) was lower than that of the HOYA NY-60 group (-0.05 ± 0.072 μm) (P =.005). The original negative spherical aberrations of the HOYA NY-60 (-0.18 μm) were measured at a pupil diameter of 5.6 mm, and for the Tecnis ZCB00 (-0.27 μm) at a pupil diameter of 6.1 mm. The aspheric IOL efficiency dropped to 0% when the pupil diameter was 3.47 mm for the Tecnis ZCB00 group and 3.71 mm for the HOYA NY-60 group. Conclusions: When the pupil diameters of patients are smaller than 3.4 mm for the Tecnis ZCB00 and 3.7 mm for the HOYA NY-60, the spherical aberration correction using these aspheric IOLs seems to be ineffective. Approximately 10% of the eyes showed smaller pupil size than the minimum effective diameter under mesopic conditions.
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