Changes of ginsenosides in Korean red ginseng (Panax ginseng) fermented by Lactobacillus plantarum M1

Bong Gwan Kim, Sin Yang Choi, Mi Ryung Kim, Hyung Joo Suh, Hyun Jin Park

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

To obtain microorganisms for the microbial conversion of ginsenosides in red ginseng powder (RGP), Lactobacillus species (M1-M4 and P1-P4) were isolated from commercial ginseng products. Strain M1 was determined to be L. plantarum by 16S rRNA sequencing. Red ginseng powder (RGP) fermented by L. plantarum M1 had a high total content of ginsenosides (142.4. mg/g) as compared to the control (121.8. mg/g). In particular, the ginsenoside metabolites Rg3, Rg5, Rk1, Compound K (CK), Rh1, and Rg2 showed a high level in the fermented RGP (65.5. mg/g) compared to the control (32.7. mg/g). During fermentation for 7 days, total sugar content decreased from 8.55. mg/g to 4. mg/g, uronic acid content reached its maximum (53.43 μg/g) at 3 days, and total ginsenoside content increased to 176.8. mg/g at 4 days. In addition, ginsenoside metabolites increased from 38.0. mg/g to 83.4. mg/g at 4 days of fermentation. Using everted instestinal sacs of rats, the fermented red ginseng showed a high transport level (10.3. mg of polyphenols/g sac) compared to non-fermented red ginseng (6.67. mg of polyphenols/g sac) after 1. h. These results confirm that fermentation with L. plantarum M1 is very useful for preparing minor ginsenoside metabolites while being safe for foods.

Original languageEnglish
Pages (from-to)1319-1324
Number of pages6
JournalProcess Biochemistry
Volume45
Issue number8
DOIs
Publication statusPublished - 2010 Aug 1

Fingerprint

Ginsenosides
Lactobacillus plantarum
Panax
Metabolites
Fermentation
Powders
Polyphenols
Sugars
Microorganisms
Rats
Uronic Acids
Acids
Lactobacillus
Food

Keywords

  • Fermented red ginseng
  • Ginsenoside metabolites
  • Lactobacillus plantarum
  • Lactobacillus species
  • Red ginseng powder

ASJC Scopus subject areas

  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Bioengineering

Cite this

Changes of ginsenosides in Korean red ginseng (Panax ginseng) fermented by Lactobacillus plantarum M1. / Kim, Bong Gwan; Choi, Sin Yang; Kim, Mi Ryung; Suh, Hyung Joo; Park, Hyun Jin.

In: Process Biochemistry, Vol. 45, No. 8, 01.08.2010, p. 1319-1324.

Research output: Contribution to journalArticle

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abstract = "To obtain microorganisms for the microbial conversion of ginsenosides in red ginseng powder (RGP), Lactobacillus species (M1-M4 and P1-P4) were isolated from commercial ginseng products. Strain M1 was determined to be L. plantarum by 16S rRNA sequencing. Red ginseng powder (RGP) fermented by L. plantarum M1 had a high total content of ginsenosides (142.4. mg/g) as compared to the control (121.8. mg/g). In particular, the ginsenoside metabolites Rg3, Rg5, Rk1, Compound K (CK), Rh1, and Rg2 showed a high level in the fermented RGP (65.5. mg/g) compared to the control (32.7. mg/g). During fermentation for 7 days, total sugar content decreased from 8.55. mg/g to 4. mg/g, uronic acid content reached its maximum (53.43 μg/g) at 3 days, and total ginsenoside content increased to 176.8. mg/g at 4 days. In addition, ginsenoside metabolites increased from 38.0. mg/g to 83.4. mg/g at 4 days of fermentation. Using everted instestinal sacs of rats, the fermented red ginseng showed a high transport level (10.3. mg of polyphenols/g sac) compared to non-fermented red ginseng (6.67. mg of polyphenols/g sac) after 1. h. These results confirm that fermentation with L. plantarum M1 is very useful for preparing minor ginsenoside metabolites while being safe for foods.",
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