Characteristics of cutaneous lymphomas in Korea according to the new WHO-EORTC classification

Report of a nationwide study

Jae Ho Han, Young Hyeh Ko, Yun Kyung Kang, Wan Seop Kim, Yoon Jung Kim, Insun Kim, Hyun Jung Kim, Soo Kee Min, Chan Kum Park, Chan Sik Park, Bong Kyung Shin, Woo Ick Yang, Young Ha Oh, Jong Sil Lee, Juhie Lee, Tae Hui Lee, Hyekyung Lee, Ho Jung Lee, Yoon Kyung Jeon, Hee Jeong Cha & 2 others Yoo Duk Choi, Chul Woo Kim

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system. Methods: A total of 517 patients were recruited during a recent 5 year-period (2006-2010) from 21 institutes and classified according to the WHO-EORTC criteria. Results: The patients included 298 males and 219 females, and the mean age at diagnosis was 49 years. The lesions preferentially affected the trunk area (40.2%). The most frequent subtypes in order of decreasing prevalence were mycosis fungoides (22.2%), peripheral T-cell lymphoma (17.2%), CD30+ T-cell lymphoproliferative disorder (13.7%), and extranodal natural killer/T (NK/T) cell lymphoma, nasal type (12.0%). Diffuse large B-cell lymphoma accounted for 11.2% of cases, half of which were secondary cutaneous involvement; other types of B-cell lymphoma accounted for less than 1% of cases. Conclusions: In comparison with data from Western countries, this study revealed relatively lower rates of mycosis fungoides and B-cell lymphoma in Korean patients, as well as higher rates of subcutaneous panniculitis-like T-cell lymphoma and NK/T cell lymphoma.

Original languageEnglish
Pages (from-to)126-132
Number of pages7
JournalKorean Journal of Pathology
Volume48
Issue number2
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Korea
Lymphoma
Mycosis Fungoides
Natural Killer T-Cells
T-Cell Lymphoma
Organizations
B-Cell Lymphoma
Skin
Research
Peripheral T-Cell Lymphoma
Neoplasms
Lymphoproliferative Disorders
Lymphoma, Large B-Cell, Diffuse
Nose
Therapeutics
T-Lymphocytes

Keywords

  • Classification
  • Cutaneous lymphoma
  • EORTC
  • World health organization

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Characteristics of cutaneous lymphomas in Korea according to the new WHO-EORTC classification : Report of a nationwide study. / Han, Jae Ho; Ko, Young Hyeh; Kang, Yun Kyung; Kim, Wan Seop; Kim, Yoon Jung; Kim, Insun; Kim, Hyun Jung; Min, Soo Kee; Park, Chan Kum; Park, Chan Sik; Shin, Bong Kyung; Yang, Woo Ick; Oh, Young Ha; Lee, Jong Sil; Lee, Juhie; Lee, Tae Hui; Lee, Hyekyung; Lee, Ho Jung; Jeon, Yoon Kyung; Cha, Hee Jeong; Choi, Yoo Duk; Kim, Chul Woo.

In: Korean Journal of Pathology, Vol. 48, No. 2, 01.01.2014, p. 126-132.

Research output: Contribution to journalArticle

Han, JH, Ko, YH, Kang, YK, Kim, WS, Kim, YJ, Kim, I, Kim, HJ, Min, SK, Park, CK, Park, CS, Shin, BK, Yang, WI, Oh, YH, Lee, JS, Lee, J, Lee, TH, Lee, H, Lee, HJ, Jeon, YK, Cha, HJ, Choi, YD & Kim, CW 2014, 'Characteristics of cutaneous lymphomas in Korea according to the new WHO-EORTC classification: Report of a nationwide study', Korean Journal of Pathology, vol. 48, no. 2, pp. 126-132. https://doi.org/10.4132/KoreanJPathol.2014.48.2.126
Han, Jae Ho ; Ko, Young Hyeh ; Kang, Yun Kyung ; Kim, Wan Seop ; Kim, Yoon Jung ; Kim, Insun ; Kim, Hyun Jung ; Min, Soo Kee ; Park, Chan Kum ; Park, Chan Sik ; Shin, Bong Kyung ; Yang, Woo Ick ; Oh, Young Ha ; Lee, Jong Sil ; Lee, Juhie ; Lee, Tae Hui ; Lee, Hyekyung ; Lee, Ho Jung ; Jeon, Yoon Kyung ; Cha, Hee Jeong ; Choi, Yoo Duk ; Kim, Chul Woo. / Characteristics of cutaneous lymphomas in Korea according to the new WHO-EORTC classification : Report of a nationwide study. In: Korean Journal of Pathology. 2014 ; Vol. 48, No. 2. pp. 126-132.
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abstract = "Background: Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system. Methods: A total of 517 patients were recruited during a recent 5 year-period (2006-2010) from 21 institutes and classified according to the WHO-EORTC criteria. Results: The patients included 298 males and 219 females, and the mean age at diagnosis was 49 years. The lesions preferentially affected the trunk area (40.2{\%}). The most frequent subtypes in order of decreasing prevalence were mycosis fungoides (22.2{\%}), peripheral T-cell lymphoma (17.2{\%}), CD30+ T-cell lymphoproliferative disorder (13.7{\%}), and extranodal natural killer/T (NK/T) cell lymphoma, nasal type (12.0{\%}). Diffuse large B-cell lymphoma accounted for 11.2{\%} of cases, half of which were secondary cutaneous involvement; other types of B-cell lymphoma accounted for less than 1{\%} of cases. Conclusions: In comparison with data from Western countries, this study revealed relatively lower rates of mycosis fungoides and B-cell lymphoma in Korean patients, as well as higher rates of subcutaneous panniculitis-like T-cell lymphoma and NK/T cell lymphoma.",
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T1 - Characteristics of cutaneous lymphomas in Korea according to the new WHO-EORTC classification

T2 - Report of a nationwide study

AU - Han, Jae Ho

AU - Ko, Young Hyeh

AU - Kang, Yun Kyung

AU - Kim, Wan Seop

AU - Kim, Yoon Jung

AU - Kim, Insun

AU - Kim, Hyun Jung

AU - Min, Soo Kee

AU - Park, Chan Kum

AU - Park, Chan Sik

AU - Shin, Bong Kyung

AU - Yang, Woo Ick

AU - Oh, Young Ha

AU - Lee, Jong Sil

AU - Lee, Juhie

AU - Lee, Tae Hui

AU - Lee, Hyekyung

AU - Lee, Ho Jung

AU - Jeon, Yoon Kyung

AU - Cha, Hee Jeong

AU - Choi, Yoo Duk

AU - Kim, Chul Woo

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Background: Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system. Methods: A total of 517 patients were recruited during a recent 5 year-period (2006-2010) from 21 institutes and classified according to the WHO-EORTC criteria. Results: The patients included 298 males and 219 females, and the mean age at diagnosis was 49 years. The lesions preferentially affected the trunk area (40.2%). The most frequent subtypes in order of decreasing prevalence were mycosis fungoides (22.2%), peripheral T-cell lymphoma (17.2%), CD30+ T-cell lymphoproliferative disorder (13.7%), and extranodal natural killer/T (NK/T) cell lymphoma, nasal type (12.0%). Diffuse large B-cell lymphoma accounted for 11.2% of cases, half of which were secondary cutaneous involvement; other types of B-cell lymphoma accounted for less than 1% of cases. Conclusions: In comparison with data from Western countries, this study revealed relatively lower rates of mycosis fungoides and B-cell lymphoma in Korean patients, as well as higher rates of subcutaneous panniculitis-like T-cell lymphoma and NK/T cell lymphoma.

AB - Background: Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system. Methods: A total of 517 patients were recruited during a recent 5 year-period (2006-2010) from 21 institutes and classified according to the WHO-EORTC criteria. Results: The patients included 298 males and 219 females, and the mean age at diagnosis was 49 years. The lesions preferentially affected the trunk area (40.2%). The most frequent subtypes in order of decreasing prevalence were mycosis fungoides (22.2%), peripheral T-cell lymphoma (17.2%), CD30+ T-cell lymphoproliferative disorder (13.7%), and extranodal natural killer/T (NK/T) cell lymphoma, nasal type (12.0%). Diffuse large B-cell lymphoma accounted for 11.2% of cases, half of which were secondary cutaneous involvement; other types of B-cell lymphoma accounted for less than 1% of cases. Conclusions: In comparison with data from Western countries, this study revealed relatively lower rates of mycosis fungoides and B-cell lymphoma in Korean patients, as well as higher rates of subcutaneous panniculitis-like T-cell lymphoma and NK/T cell lymphoma.

KW - Classification

KW - Cutaneous lymphoma

KW - EORTC

KW - World health organization

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