Characteristics of patients with chronic obstructive pulmonary disease at the first visit to a pulmonary medical center in Korea: The KOrea COpd subgroup study team cohort

Jung Yeon Lee, Gyu Rak Chon, Chin Kook Rhee, Deog Kyeom Kim, Hyoung Kyu Yoon, Jin Hwa Lee, Kwang Ha Yoo, Sang Haak Lee, Sang Yeub Lee, Tae Eun Kim, Tae Hyung Kim, Yong Bum Park, Yong Il Hwang, Young Sam Kim, Ki Suck Jung

Research output: Contribution to journalArticle

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Abstract

The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD Subgroup Study team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 ± 7.8 years) who were enrolled from 45 tertiary and universityaffiliated hospitals from December 2011 to October 2014. The initial evaluation for all patients included pulmonary function tests (PFT), 6-minute walk distance (6MWD), COPD Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, and the COPD-specific version of St. George's Respiratory Questionnaire (SGRQ-C). Here, we report the comparison of baseline characteristics between patients with early- (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage I and II/groups A and B) and late-stage COPD (GOLD stage III and IV/groups C and D). Among all patients, the mean postbronchodilator FEV1 was 55.8% ± 16.7% of the predicted value, and most of the patients were in GOLD stage II (520, 56.9%) and group B (399, 42.0%). The number of exacerbations during one year prior to the first visit was significantly lower in patients with early COPD (0.4 vs. 0.9/0.1 vs. 1.2), as were the CAT score (13.9 vs. 18.3/13.5 vs. 18.1), mMRC (1.4 vs. 2.0/1.3 vs.1.9), and SGRQ-C total score (30.4 vs. 42.9/29.1 vs. 42.6) compared to late-stage COPD (all P < 0.001). Common comorbidities among all patients were hypertension (323, 37.7%), diabetes mellitus (139, 14.8%), and depression (207, 23.6%). The data from patients with early COPD will provide important information towards early detection, proper initial management, and design of future studies.

Original languageEnglish
Pages (from-to)553-560
Number of pages8
JournalJournal of Korean Medical Science
Volume31
Issue number4
DOIs
Publication statusPublished - 2016 Jan 1

Fingerprint

Korea
Chronic Obstructive Pulmonary Disease
Cohort Studies
Lung
Biomedical Research
Respiratory Function Tests
Tertiary Care Centers
Dyspnea
Multicenter Studies
Observational Studies
Comorbidity
Diabetes Mellitus
Hypertension

Keywords

  • Chronic obstructive
  • Pulmonary disease
  • Questionnaires
  • Respiratory function tests

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Characteristics of patients with chronic obstructive pulmonary disease at the first visit to a pulmonary medical center in Korea : The KOrea COpd subgroup study team cohort. / Lee, Jung Yeon; Chon, Gyu Rak; Rhee, Chin Kook; Kim, Deog Kyeom; Yoon, Hyoung Kyu; Lee, Jin Hwa; Yoo, Kwang Ha; Lee, Sang Haak; Lee, Sang Yeub; Kim, Tae Eun; Kim, Tae Hyung; Park, Yong Bum; Hwang, Yong Il; Kim, Young Sam; Jung, Ki Suck.

In: Journal of Korean Medical Science, Vol. 31, No. 4, 01.01.2016, p. 553-560.

Research output: Contribution to journalArticle

Lee, JY, Chon, GR, Rhee, CK, Kim, DK, Yoon, HK, Lee, JH, Yoo, KH, Lee, SH, Lee, SY, Kim, TE, Kim, TH, Park, YB, Hwang, YI, Kim, YS & Jung, KS 2016, 'Characteristics of patients with chronic obstructive pulmonary disease at the first visit to a pulmonary medical center in Korea: The KOrea COpd subgroup study team cohort', Journal of Korean Medical Science, vol. 31, no. 4, pp. 553-560. https://doi.org/10.3346/jkms.2016.31.4.553
Lee, Jung Yeon ; Chon, Gyu Rak ; Rhee, Chin Kook ; Kim, Deog Kyeom ; Yoon, Hyoung Kyu ; Lee, Jin Hwa ; Yoo, Kwang Ha ; Lee, Sang Haak ; Lee, Sang Yeub ; Kim, Tae Eun ; Kim, Tae Hyung ; Park, Yong Bum ; Hwang, Yong Il ; Kim, Young Sam ; Jung, Ki Suck. / Characteristics of patients with chronic obstructive pulmonary disease at the first visit to a pulmonary medical center in Korea : The KOrea COpd subgroup study team cohort. In: Journal of Korean Medical Science. 2016 ; Vol. 31, No. 4. pp. 553-560.
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N2 - The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD Subgroup Study team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 ± 7.8 years) who were enrolled from 45 tertiary and universityaffiliated hospitals from December 2011 to October 2014. The initial evaluation for all patients included pulmonary function tests (PFT), 6-minute walk distance (6MWD), COPD Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, and the COPD-specific version of St. George's Respiratory Questionnaire (SGRQ-C). Here, we report the comparison of baseline characteristics between patients with early- (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage I and II/groups A and B) and late-stage COPD (GOLD stage III and IV/groups C and D). Among all patients, the mean postbronchodilator FEV1 was 55.8% ± 16.7% of the predicted value, and most of the patients were in GOLD stage II (520, 56.9%) and group B (399, 42.0%). The number of exacerbations during one year prior to the first visit was significantly lower in patients with early COPD (0.4 vs. 0.9/0.1 vs. 1.2), as were the CAT score (13.9 vs. 18.3/13.5 vs. 18.1), mMRC (1.4 vs. 2.0/1.3 vs.1.9), and SGRQ-C total score (30.4 vs. 42.9/29.1 vs. 42.6) compared to late-stage COPD (all P < 0.001). Common comorbidities among all patients were hypertension (323, 37.7%), diabetes mellitus (139, 14.8%), and depression (207, 23.6%). The data from patients with early COPD will provide important information towards early detection, proper initial management, and design of future studies.

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