Characterization of anomalous movements of spherical living cells on a silicon dioxide glassy substrate

Myeonggu Son, Gyudo Lee, Jongsang Son, Seungyeop Choi, Youngho Kim, Sei Young Lee, Young Ro Yoon, Dae Sung Yoon, Sang Woo Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The random walk of spherical living cells on a silicon dioxide glassy substrate was studied experimentally and numerically. This random walk trajectory exhibited erratic dancing, which seemingly obeyed anomalous diffusion (i.e., Lévy-like walk) rather than normal diffusion. Moreover, the angular distribution (-π to π) of the cells' trajectory followed a "U-shaped pattern" in comparison to the uniform distribution seen in the movements of negatively charged polystyrene microspheres. These effects could be attributable to the homeostasis-driven structural resilient character of cells and physical interactions derived from temporarily retained nonspecific binding due to weak forces between the cells and substrates. Our results provide new insights into the stochastic behavior of mesoscopic biological particles with respect to structural properties and physical interactions.

Original languageEnglish
Article number014122
JournalBiomicrofluidics
Volume9
Issue number1
DOIs
Publication statusPublished - 2015 Jan 7

Fingerprint

Silicon Dioxide
Silica
Cells
Trajectories
silicon dioxide
random walk
Angular distribution
Polystyrenes
Substrates
cells
Microspheres
trajectories
homeostasis
Structural properties
Cell Communication
polystyrene
Homeostasis
angular distribution
interactions

ASJC Scopus subject areas

  • Molecular Biology
  • Materials Science(all)
  • Genetics
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

Cite this

Characterization of anomalous movements of spherical living cells on a silicon dioxide glassy substrate. / Son, Myeonggu; Lee, Gyudo; Son, Jongsang; Choi, Seungyeop; Kim, Youngho; Lee, Sei Young; Yoon, Young Ro; Yoon, Dae Sung; Lee, Sang Woo.

In: Biomicrofluidics, Vol. 9, No. 1, 014122, 07.01.2015.

Research output: Contribution to journalArticle

Son, Myeonggu ; Lee, Gyudo ; Son, Jongsang ; Choi, Seungyeop ; Kim, Youngho ; Lee, Sei Young ; Yoon, Young Ro ; Yoon, Dae Sung ; Lee, Sang Woo. / Characterization of anomalous movements of spherical living cells on a silicon dioxide glassy substrate. In: Biomicrofluidics. 2015 ; Vol. 9, No. 1.
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